Zobrazeno 1 - 10
of 136
pro vyhledávání: '"K. Ihnken"'
Autor:
W. Hassanein, L. Kane, P. Lezberg, A. Hassanein, N. Dang, S. LaFrancesca, A. Kaw, S. Brann, M. Omara, S. Reddy, K. Ihnken, M. Al Salihi, F. Zafar, T. Khayal
Publikováno v:
The Journal of Heart and Lung Transplantation. 42:S278-S279
Publikováno v:
Vascular surgery. 35(2)
Despite successful surgical revascularization of ischemic limbs, a local and systemic reperfusion injury may occur after normal blood reperfusion. Recent experimental and clinical application of controlled limb reperfusion in Europe has demonstrated
Autor:
K, Ihnken
Publikováno v:
The Thoracic and cardiovascular surgeon. 48(1)
Current myocardial protection techniques in cyanotic immature hearts are not optimal. Despite successful surgical correction of congenital cardiac defects causing hypoxemia, myocardial dysfunction remains the leading cause of postoperative mortality.
Publikováno v:
The Journal of thoracic and cardiovascular surgery. 110(4 Pt 2)
The conventional way to start cardiopulmonary bypass is to prime the cardiopulmonary bypass circuit with hyperoxemic blood (oxygen tension about 400 mm Hg) and deliver cardioplegic solutions at similar oxygen tension levels. This study tests the hypo
Publikováno v:
The Journal of thoracic and cardiovascular surgery. 110(4 Pt 2)
This study tests the hypothesis that reoxygenation of cyanotic immature hearts when starting cardiopulmonary bypass produces an "unintended" reoxygenation injury that (1) nullifies the cardioprotective effects of blood cardioplegia and (2) is avoidab
Publikováno v:
The Journal of thoracic and cardiovascular surgery. 110(4 Pt 2)
Previous studies show that (1) hypoxemia depletes immature myocardium of amino acid substrates and their replenishment improves ischemic tolerance, (2) reoxygenation on cardiopulmonary bypass causes oxygen-mediated damage without added ischemia, and
Publikováno v:
The Journal of thoracic and cardiovascular surgery. 110(4 Pt 2)
Coenzyme Q10 (CoQ10) is a natural mitochondrial respiratory chain constituent with antioxidant properties. This study tests the hypothesis that CoQ10 administered before the onset of reoxygenation on cardiopulmonary bypass, can reduce oxygen-mediated
Publikováno v:
The Journal of thoracic and cardiovascular surgery. 110(4 Pt 2)
This study tests the hypothesis that antioxidants administered before reoxygenation can reduce oxygen-mediated damage and improve myocardial performance. Of 25 Duroc-Yorkshire piglets (2 to 3 weeks, 3 to 5 kg) five underwent 60 minutes of cardiopulmo
Publikováno v:
The Journal of thoracic and cardiovascular surgery. 110(4 Pt 2)
Twenty-one immature piglets (3 weeks old) underwent 30 minutes of aortic clamping with hypocalcemic glutamate/aspartate blood cardioplegia. Six piglets underwent hyperoxemic cardiopulmonary bypass and blood cardioplegia without preceding hypoxemia (c
Publikováno v:
The Journal of thoracic and cardiovascular surgery. 110(4 Pt 2)
This study tests the interaction between oxygen tension and cardioplegic composition on nitric oxide production and oxidant damage during reoxygenation of previously cyanotic hearts. Of 35 Duroc-Yorkshire piglets (2 to 3 weeks, 3 to 5 kg), six underw