Zobrazeno 1 - 10
of 51
pro vyhledávání: '"K. I. Kirsanov"'
Autor:
O. V. Morozova, A. Yu. Bukina, V. G. Popova, G. I. Khairieva, G. R. Sagitova, G. A. Belitsky, M. G. Yakubovskaya, K. I. Kirsanov, V. P. Maksimova
Publikováno v:
Успехи молекулярной онкологии, Vol 11, Iss 3, Pp 41-55 (2024)
One of the factors associated with increased morbidity of malignant neoplasms is environmental pollution with cancerogenic compounds including pesticides. Until recently, stable organic pollutant insecticide dichlorodiphenyltrichloroethane (DDT) was
Externí odkaz:
https://doaj.org/article/679ed9d93fbd4dfcb441421bfeffdcba
Autor:
V. P. Maksimova, J. V. Makus, V. G. Popova, O. G. Usalka, G. A. Belitsky, M. G. Yakubovskaya, K. I. Kirsanov
Publikováno v:
Сибирский онкологический журнал, Vol 23, Iss 4, Pp 125-140 (2024)
Background. DNA methylation is a crucial mechanism of epigenetic regulation of transcription. Disturbances in DNA methylation mechanism are associated with various malignancies such as acute myeloid leukaemia, breast cancer, prostate cancer, etc. Inf
Externí odkaz:
https://doaj.org/article/2ac159153f0b4d2aa0cb5e53074cca6a
Autor:
L. G. Solenova, N. I. Ryzhova, I. A. Antonova, G. A. Belitsky, K. I. Kirsanov, M. G. Yakubovskaya
Publikováno v:
Issledovaniâ i Praktika v Medicine, Vol 11, Iss 3, Pp 85-102 (2024)
The development of omics technologies and sequencing has significantly expanded the understanding of the role of microorganisms that inhabit various human organs and collectively make up its microbiota in the development of cancer. The extensive lite
Externí odkaz:
https://doaj.org/article/283f69ea0f164acabe77486e5d3ed249
Autor:
O. A. Vlasova, I. A. Antonova, Kh. M. Magomedova, M. A. Usolkina, K. I. Kirsanov, G. A. Belitsky, T. T. Valiev, M. G. Yakubovskaya
Publikováno v:
Успехи молекулярной онкологии, Vol 11, Iss 2, Pp 8-28 (2024)
In preparing the review, articles on the functioning of the reverse transcriptase enzyme of endogenous repeat sequences LINE1, the mechanisms of action and antitumor activity of viral reverse transcriptase inhibitors. Articles available in the biomed
Externí odkaz:
https://doaj.org/article/50ce600013924932ab99b89de763f824
Autor:
G. A. Belitsky, K. I. Kirsanov, E. A. Lesovaya, E. M. Zhidkova, I. A. Khitrovo, M. G. Yakubovskaya
Publikováno v:
Сибирский онкологический журнал, Vol 22, Iss 5, Pp 145-160 (2023)
The main aim of the study is to analyze modern knowledge on endocrine disruptors, non-genotoxic carcinogens, contributing significantly to the total level of contamination of the biosphere by anthropogenic blastomogens.Material and Methods. For the r
Externí odkaz:
https://doaj.org/article/288141d2bd18473f9a710f4343594567
Autor:
G. A. Belitsky, K. I. Kirsanov, E. A. Lesovaya, V. P. Maksimova, L. V. Krivosheeva, M. G. Yakubovskaya
Publikováno v:
Успехи молекулярной онкологии, Vol 10, Iss 3, Pp 24-35 (2023)
The incidence and mortality of malignant neoplasms of non-reproductive organs both carcinomas and sarcomas in men is one and a half times higher than in women. This is based on genetic differences, which are superimposed by patterns of epigenetic reg
Externí odkaz:
https://doaj.org/article/dbb726e9485c41588477975fa78ff5fe
Autor:
A. M. Scherbakov, T. I. Fetisov, D. V. Sorokin, V. Yu. Zinovieva, N. I. Moiseeva, L. A. Laletina, E. M. Kirilin, A. E. Manikaylo, L. Ya. Fomina, L. V. Mekheda, B. Yu. Bokhyan, E. A. Lesovaya, L. S. Trukhanova, T. G. Gor’kova, E. E. Antoshina, O. V. Morozova, K. I. Kirsanov, M. G. Yakubovskaya
Publikováno v:
Успехи молекулярной онкологии, Vol 9, Iss 2, Pp 58-65 (2022)
Introduction. The identification of predictive factors is a cornerstone task of modern oncology. The development of new targeted drugs determines the need for prediction of chemosensitivity of each patient to the prescribed therapy, in this regard, t
Externí odkaz:
https://doaj.org/article/71afdbbddba344529bf70f023fe79b06
Autor:
E. M. Zhidkova, D. D. Grigoreva, E. S. Lylova, V. P. Maksimova, G. R. Sagitova, G. I. Khayrieva, E. S. Trapeznikova, K. I. Kirsanov, M. G. Yakubovskaya, E. A. Lesovaya
Publikováno v:
Сибирский онкологический журнал, Vol 21, Iss 3, Pp 50-60 (2022)
Objective: screening of previously selected DDIT4 inhibitors by their ability to suppress basal and glucocorticoid-induced expression of this gene in breast cancer (BC) cells, as well as evaluation of antiproliferative and cytotoxic effects of the st
Externí odkaz:
https://doaj.org/article/0a86cb5f69c84ab6be5b86b5ee7b8015
Autor:
D. D. Grigorieva, E. M. Zhidkova, E. S. Lylova, D. V. Demina, K. I. Kirsanov, G. A. Belitsky, M. G. Yakubovskaya, E. A. Lesovaya
Publikováno v:
Успехи молекулярной онкологии, Vol 9, Iss 1, Pp 42-47 (2022)
Introduction. Glucocorticoids are often used in combination therapy for breast cancer as an adjuvant to increase therapeutic effects of the main cytotoxic drug and to reduce side effects of chemotherapy. However, glucocorticoids can cause serious com
Externí odkaz:
https://doaj.org/article/cae9ac30018c4ef68df2f5530867d10e
Autor:
D. D. Grigoreva, E. M. Zhidkova, E. S. Lylova, A. D. Enikeev, K. I. Kirsanov, G. A. Belitsky, M. G. Yakubovskaya, E. A. Lesovaya
Publikováno v:
Успехи молекулярной онкологии, Vol 9, Iss 4 (2022)
Introduction. Current chemotherapy of breast cancer has a wide range of disadvantages, in particular, the development of therapy-related infections and hormonal imbalance. Combination of main cytostatic with glucocorticoids allows to broaden its ther
Externí odkaz:
https://doaj.org/article/0fd1933c86234903a378d022060954b1