Unraveling weak and short South Asian wet season in the Early Eocene warmth

Autor: S. Abhik, Fabio A. Capitanio, Dietmar Dommenget, B. N. Goswami, Alex Farnsworth, David K. Hutchinson, Julie M. Arblaster, Daniel J. Lunt, Sebastian Steinig

Publikováno v: Communications Earth & Environment, Vol 5, Iss 1, Pp 1-12 (2024)

Abstract The timing and causative factors underlying the Asian summer monsoon initiation remain contentious as recent proxy data and modeling studies suggested the existence of a wet-dry monsoon-like climate from the Cretaceous period. Leveraging an

Externí odkaz: https://doaj.org/article/e83e50ae6d4241fabc861c497328c6c5

East Antarctic warming forced by ice loss during the Last Interglacial

Autor: David K. Hutchinson, Laurie Menviel, Katrin J. Meissner, Andrew McC. Hogg

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)

Abstract During the Last Interglacial (LIG; 129-116 thousand years before present), the Antarctic ice sheet (AIS) was 1 to 7 m sea level equivalent smaller than at pre-industrial. Here, we assess the climatic impact of partial AIS melting at the LIG

Externí odkaz: https://doaj.org/article/046d1278e6434c999ee37147ed4e3a49

Reproducible and relocatable regional ocean modelling: fundamentals and practices

Autor: J. Polton, J. Harle, J. Holt, A. Katavouta, D. Partridge, J. Jardine, S. Wakelin, J. Rulent, A. Wise, K. Hutchinson, D. Byrne, D. Bruciaferri, E. O'Dea, M. De Dominicis, P. Mathiot, A. Coward, A. Yool, J. Palmiéri, G. Lessin, C. G. Mayorga-Adame, V. Le Guennec, A. Arnold, C. Rousset

Publikováno v: Geoscientific Model Development, Vol 16, Pp 1481-1510 (2023)

In response to an increasing demand for bespoke or tailored regional ocean modelling configurations, we outline fundamental principles and practices that can expedite the process to generate new configurations. The paper develops the principle of rep

Externí odkaz: https://doaj.org/article/8c6899a9059d42b7b462ebe30e4e28f1

Refractive Growth of the Crystalline Lens in the Infant Aphakia Treatment Study

Autor: Thaddeus S. McClatchey, MD, Scott R. Lambert, MD, David G. Morrison, MD, Stacey J. Kruger, MD, Lorri B. Wilson, MD, Scott K. McClatchey, MD, Scott R. Lambert, MD (Study Chair), Lindreth DuBois, MEd, MMSc, CO, COMT (National Coordinator), Azhar Nizam, MS (Director), Qi Long, PhD (former Director), Michael J. Lynn, MS (former Director), Betsy Bridgman, BS, Marianne Celano, PhD, Julia Cleveland, MS, George Cotsonis, MS, Carey Drews-Botsch, PhD, Nana Freret, MSN, Lu Lu, MS, Seegar Swanson, Thandeka Tutu-Gxashe, MPH, E. Eugenie Hartmann, PhD (Director), Anna K. Carrigan, MPH, Clara Edwards, Claudio Busettini, PhD, Samuel Hayley, Eleanor Lewis, Alicia Kindred Joost Felius, PhD, Edward G. Buckley, MD, David A. Plager, MD, M. Edward Wilson, MD, Lindreth DuBois, MEd, MMSc, Carolyn Drews-Botsch, PhD, E. Eugenie Hartmann, PhD, Donald F. Everett, MA, Michael J. Lynn, MS, Qi Long, PhD, Azhar Nizam, MS, Joost Felius, PhD, Margaret Bozic, CCRC, COA, Ann Holleschau, BA, Buddy Russell, COMT, Michael Ward, Carol Bradham, COA, Deborah K. Vanderveen, MD, Theresa A. Mansfield, RN, Kathryn Bisceglia Miller, OD, Tamar Winter, RN, Stephen P. Christiansen, MD, Erick D. Bothun, MD, Jason Jedlicka, OD, Patricia Winters, OD, Jacob Lang, OD, Jill S. Anderson, MD, Elias I. Traboulsi, MD, Susan Crowe, BS, COT, Heather Hasley Cimino, OD, Faruk Orge, MD, Megin Kwiatkowski, Beth Colon, Angela Meador, COA, MHA, Kimberly G. Yen, MD, Maria Castanes, MPH, Alma Sanchez, COA, Shirley York, OD, Stacy Malone, COA, Margaret Olfson, Gihan Romany, MBChB, COMT, CCRC, David T. Wheeler, MD, Ann U. Stout, MD, Paula Rauch, OT, CRC, Kimberly Beaudet, CO, COMT, Pam Berg, CO, COMT, Lorri Wilson, MD, Amy K. Hutchinson, MD, Lindreth Dubois, MEd, MMSc, CO, COMT, Rachel Robb, MMSc, CO, COMT, Marla J. Shainberg, CO, Sharon F. Freedman, MD, Lois Duncan, BS, CO, COMT, B.W. Phillips, FCLSA, John T. Petrowski, OD, Sarah Jones, MS, David Morrison, MD, Sandy Owings, COA, CCRP, Ron Biernacki, CO, COMT, Christine Franklin, COT, Scott Ruark, Daniel E. Neely, MD, Michele Whitaker, COMT, CCRP, Donna Bates, COA, Dana Donaldson, OD, Stacey Kruger, MD, Charlotte Tibi, CO, Susan Vega, David R. Weakley, MD, David R. Stager, Jr., M.D., Clare Dias, CO, Debra L. Sager, Todd Brantley, OD, Bonnie Miller, PhD, Eva Lutz, CO, Lisa Davis, Robert Hardy, PHD (Chair), Eileen Birch, PhD, Ken Cheng, MD, Richard Hertle, MD, Craig Kollman, PhD, Marshalyn Yeargin-Allsopp, MD (resigned), Cyd McDowell, Allen Beck, MD

Publikováno v: Ophthalmology Science, Vol 2, Iss 4, Pp 100208- (2022)

Objective: To compare the rate of refractive growth (RRG3) of the crystalline lens (“lens”) versus the eye excluding the lens (“globe”) for the fellow, noncataractous eyes of participants in the Infant Aphakia Treatment Study. Design: Retrosp

Externí odkaz: https://doaj.org/article/8902367540a64249bec183ced1682f5d

Pharmacokinetics and biodistribution of extracellular vesicles administered intravenously and intranasally to Macaca nemestrina

Autor: Tom Driedonks, Linglei Jiang, Bess Carlson, Zheng Han, Guanshu Liu, Suzanne E. Queen, Erin N. Shirk, Olesia Gololobova, Zhaohao Liao, Lyle H. Nyberg, Gabriela Lima, Liliia Paniushkina, Marta Garcia‐Contreras, Kayla Schonvisky, Natalie Castell, Mitchel Stover, Selena Guerrero‐Martin, Riley Richardson, Barbara Smith, Vasiliki Mahairaki, Charles P. Lai, Jessica M. Izzi, Eric K. Hutchinson, Kelly A. M. Pate, Kenneth W. Witwer

Publikováno v: Journal of Extracellular Biology, Vol 1, Iss 10, Pp n/a-n/a (2022)

Abstract Extracellular vesicles (EVs) have potential in disease treatment since they can be loaded with therapeutic molecules and engineered for retention by specific tissues. However, questions remain on optimal dosing, administration and pharmacoki

Externí odkaz: https://doaj.org/article/6033ca7d2ad846969268515852ea161c