Zobrazeno 1 - 10
of 134
pro vyhledávání: '"K. Haukka"'
Autor:
Anni A. Antikainen, Jani K. Haukka, Anmol Kumar, Anna Syreeni, Stefanie Hägg-Holmberg, Anni Ylinen, Elina Kilpeläinen, Anastasia Kytölä, Aarno Palotie, Jukka Putaala, Lena M. Thorn, Valma Harjutsalo, Per-Henrik Groop, Niina Sandholm, the FinnDiane Study Group
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Individuals with type 1 diabetes (T1D) carry a markedly increased risk of stroke, with distinct clinical and neuroimaging characteristics as compared to those without diabetes. Using whole-exome or whole-genome sequencing of 1,051 individual
Externí odkaz:
https://doaj.org/article/365346fbb64840359eb3f8e5a30d4bfe
Autor:
Niina Sandholm, Ronja Hotakainen, Jani K. Haukka, Fanny Jansson Sigfrids, Emma H. Dahlström, Anni A. Antikainen, Erkka Valo, Anna Syreeni, Elina Kilpeläinen, Anastasia Kytölä, Aarno Palotie, Valma Harjutsalo, Carol Forsblom, Per-Henrik Groop, on behalf of the FinnDiane Study Group
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-18 (2022)
Abstract Background Dyslipidemia is a major risk factor for cardiovascular disease, and diabetes impacts the lipid metabolism through multiple pathways. In addition to the standard lipid measurements, apolipoprotein concentrations provide added aware
Externí odkaz:
https://doaj.org/article/3656e2df02434cbca5a5f1c25c95cd07
Autor:
Olli P. O. Nevalainen, Saana Horstia, Sanna Laakkonen, Jarno Rutanen, Jussi M. J. Mustonen, Ilkka E. J. Kalliala, Hanna Ansakorpi, Hanna-Riikka Kreivi, Pauliina Kuutti, Juuso Paajanen, Seppo Parkkila, Erja-Leena Paukkeri, Markus Perola, Negar Pourjamal, Andreas Renner, Tuomas Rosberg, Taija Rutanen, Joni Savolainen, Solidarity Finland Investigators, Jari K. Haukka, Gordon H. Guyatt, Kari A. O. Tikkinen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-6 (2022)
Many survivors of COVID-19 experience persistent symptoms, continuing beyond three months from the onset of infection. In this study, authors investigate the effect of remdesivir on recovery and long-COVID-19 symptoms, as well as quality of life and
Externí odkaz:
https://doaj.org/article/813e0440ada04ef798794a926f59ee3a
Autor:
Niina Sandholm, Jani K Haukka, Iiro Toppila, Erkka Valo, Valma Harjutsalo, Carol Forsblom, Per-Henrik Groop
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Abstract Urinary albumin excretion is an early sign of diabetic kidney disease, affecting every third individual with diabetes. Despite substantial estimated heritability, only variants in the GLRA3 gene have been genome-wide significantly associated
Externí odkaz:
https://doaj.org/article/86e9a250dc08488f9a5488cfa33be9b5
Autor:
Anni A. Antikainen, Jani K. Haukka, Anmol Kumar, Anna Syreeni, Stefanie Hägg-Holmberg, Anni Ylinen, Elina Kilpeläinen, Anastasia Kytölä, Aarno Palotie, Jukka Putaala, Lena M. Thorn, Valma Harjutsalo, Per-Henrik Groop, Niina Sandholm
AimsIndividuals with type 1 diabetes (T1D) carry a markedly increased risk of stroke, with distinct clinical and neuroimaging characteristics as compared to those without diabetes. Using whole-genome sequencing (WGS) and whole-exome sequencing (WES),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8442e117bfb3611b5495aa353028851
https://doi.org/10.1101/2022.11.30.22282752
https://doi.org/10.1101/2022.11.30.22282752
Autor:
Olli P O Nevalainen, Saana Horstia, Sanna Laakkonen, Jarno Rutanen, Jussi Mustonen, Ilkka Kalliala, Hanna Ansakorpi, Hanna-Riikka Kreivi, Pauliina Kuutti, Juuso Paajanen, Seppo Parkkila, Erja-Leena Paukkeri, Markus Perola, Negar Pourjamal, Andreas Renner, Tuomas Rosberg, Taija Rutanen, Joni Savolainen, Jari K Haukka, Gordon H Guyatt, Kari A Tikkinen
Publikováno v:
Open Forum Infectious Diseases. 9
Background Coronavirus disease 2019 (COVID-19) patients frequently suffer from long-term sequelae, often called “long COVID” or “post COVID-19 condition”. Remdesivir, given in early disease, decreases the risk of hospitalization and potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4af8f6dd6d1a54087689d41f57eada8
https://doi.org/10.1093/ofid/ofac492.965
https://doi.org/10.1093/ofid/ofac492.965
Autor:
M. Congo‐Ouedraogo, T. Poncin, L. Sangaré, M. Mérimèche, A. Braille, H. Jacquier, A.‐S. Ouedraogo, E. Dah, I. Traore, J. Corander, K. Haukka, B. Berçot, S. Godreuil
Publikováno v:
Journal of the European Academy of Dermatology and Venereology. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67fe4f8e88a2707618355b078f653fca
https://doi.org/10.1111/jdv.18037
https://doi.org/10.1111/jdv.18037
Autor:
Jani K. Haukka, Niina Sandholm, C. Sidore, Anna Syreeni, P.-H. Groop, Valma Harjutsalo, Francesco Cucca
Publikováno v:
Journal of Internal Medicine
Background Type 1 diabetes (T1D) is an autoimmune disease affecting individuals in the early years of life. Although previous studies have identified genetic loci influencing T1D diagnosis age, these studies did not investigate the genome with high r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0613e6baed39d8797b7fb84825e2d50b
https://doi.org/10.1111/joim.13187
https://doi.org/10.1111/joim.13187
Autor:
Rachel G. Miller, Erkka Valo, Jani K. Haukka, Tina Costacou, Barbara E.K. Klein, Beata Gyorgy, Joseph V. Bonventre, Katalin Susztak, Hillary A. Keenan, James H. Warram, Marlon Pragnell, Ivan G. Shabalin, Andrew D. Paterson, Stephen S. Rich, Takaharu Ichimura, Jingjing Cao, Suna Onengut-Gumuscu, Ronald Klein, Kristina O’Neil, Eiichiro Satake, Marcus G. Pezzolesi, Josyf C. Mychaleckyj, Niina Sandholm, Christian Dina, Andrzej T. Galecki, George L. King, Trevor J. Orchard, Samy Hadjadj, Per-Henrik Groop, Adam M. Smiles, Carol Forsblom, Andrzej S. Krolewski, David-Alexandre Trégouët, Tarunveer S. Ahluwalia, Peter Rossing, Ron Korstanje
Publikováno v:
Journal of the American Society of Nephrology
Journal of the American Society of Nephrology, American Society of Nephrology, 2021, 32 (10), pp.2634-2651. ⟨10.1681/ASN.2020101457⟩
Journal of the American Society of Nephrology, American Society of Nephrology, 2021, 32 (10), pp.2634-2651. ⟨10.1681/ASN.2020101457⟩
Background Rare variants in gene coding regions likely have a greater impact on disease-related phenotypes than common variants through disruption of their encoded protein. We searched for rare variants associated with onset of end stage kidney disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d8ebafcd82a8106854f67bac0a578d
http://hdl.handle.net/20.500.12278/123983
http://hdl.handle.net/20.500.12278/123983
Autor:
Aarno Palotie, A. Antikainen, Erkka Valo, Per-Henrik Groop, Niina Sandholm, Jani K. Haukka, Valma Harjutsalo, Fanny Jansson Sigfrids, Carol Forsblom, Ronja Hotakainen, Anna Syreeni, Elina Kilpeläinen, Emma H. Dahlström, Anastasia Kytölä
Dyslipidemia is a major risk factor for cardiovascular disease. While common genetic variants are known to modestly affect the serum lipid concentrations, rare genetic mutations can cause monogenic forms of hypercholesteremia and other genetic disord
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f68be232b707baa24770f69f2601372
https://doi.org/10.1101/2021.09.19.21263610
https://doi.org/10.1101/2021.09.19.21263610