Zobrazeno 1 - 7
of 7
pro vyhledávání: '"K. H.H. Kwok"'
Publikováno v:
Current Drug Metabolism. 9:276-279
Previously we have shown that E2 down regulates S-COMT expression. Here the effects of four phthalate esters and 4-(tert-octyl)phenol on the intra-cellular levels of S-COMT and COMT activity were studied in MCF-7 cells as a measure of estrogenic acti
Publikováno v:
Cellular and Molecular Neurobiology. 20:483-496
1. To investigate the potency of a novel immunotoxin that is specific for glutamate receptor GluR1, a subunit of the α-amino-3-hydroxy-5-methyl-4-isoxazole-propionate (AMPA)-type receptor channel, immunolesioning was performed.
Publikováno v:
Brain Research. 846:154-163
In the present study, a comparison of potency between a commercially available immunotoxin, 192-immunoglobulin-SAP (192-IgG), and a novel immunotoxin produced in our laboratory, anti-p75-anti-mouse IgG-trichosanthin conjugates (p75-TCS), was conducte
Publikováno v:
Neurochemistry International. 33:567-572
Immunoreactivity for γ-aminobutyric acid transaminase (GABA-T), a degradation enzyme for GABA, was localized by immunocytochemistry in the rat neostriatum and the globus pallidus using a monoclonal antibody. Immunoreactivity for GABA-T was found pri
Autor:
Mhw Kung, Shu-Leong Ho, L. T. Burka, P. W.L. Ho, David B. Ramsden, K. H.H. Kwok, A. C.Y. Chu, J. W.M. Ho, K. C. Leung, C. E. Garner
Publikováno v:
Current drug metabolism. 9(4)
Commercial PCB mixtures have been shown to induce liver tumors in female rats and this effect has been attributed to the effects of PCBs on estrogen metabolism. Catechol metabolites of PCBs are potent inhibitors of COMT activity and are likely to con
Publikováno v:
Neuroscience. 96(3)
In the present study, a novel GluR2 receptor-specific immunotoxin was produced. The immunotoxin was produced by conjugation of molecules of trichosanthin, a ribosome inactivating protein, with goat anti-mouse immunoglobulin molecules. The secondary a
Publikováno v:
Brain research. 778(1)
Glutamate excitocytotoxicity is implied in the cause of neuronal degeneration in the neostriatum, in which the toxicity may be mediated by different families of glutamate receptors. The precise cellular localization of α-amino-3-hydroxy-5-methyl-4-i