Cladribine modifies functional properties of microglia

Autor: Anna Borch Weber, Maria L. Elkjaer, L. Ø. Jørgensen, Fex Svenningsen, K. H. Hyrlov, Zsolt Illes, A. E. Pedersen

Publikováno v: Jørgensen, L Ø, Hyrlov, K H, Elkjaer, M L, Weber, A B, Pedersen, A E, Svenningsen, F & Illes, Z 2020, ' Cladribine modifies functional properties of microglia ', Clinical and Experimental Immunology, vol. 201, no. 3, pp. 328-340 . https://doi.org/10.1111/cei.13473
Clinical and Experimental Immunology
Jørgensen, L Ø, Hyrlov, K H, Elkjaer, M L, Weber, A B, Pedersen, A E, Svenningsen, Å F & Illes, Z 2020, ' Cladribine modifies functional properties of microglia ', Clinical and Experimental Immunology, vol. 201, no. 3, pp. 328-340 . https://doi.org/10.1111/cei.13473

Summary Cladribine (CdA), an oral prodrug approved for the treatment of relapsing multiple sclerosis, selectively depletes lymphocytes. CdA passes the blood–brain barrier, suggesting a potential effect on central nervous system (CNS) resident cells

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https://findresearcher.sdu.dk:8443/ws/files/171295469/cei.13473.pdf