Zobrazeno 1 - 10
of 242
pro vyhledávání: '"K. Grandy"'
Autor:
Hubert H. M. Van Tol, Pierre F. Spano, Pierre Sokoloff, David R. Sibley, Philip Seeman, Goran Sedvall, Jean-Charles Schwartz, Bernard Scatton, Kim A. Neve, Maria Cristina Missale, Saloman Z. Langer, John W. Kebabian, David K. Grandy, Raul R. Gainetdinov, Gilberto Fisone, Stefano Espinoza, Olivier Civelli, Marc G. Caron, Arvid Carlsson, Emiliana Borrelli, Jean-Martin Beaulieu
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2023
Dopamine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Dopamine Receptors [373]) are commonly divided into D1-like (D1 and D5) and D2-like (D2, D3 and D4) families, where the endogenous agonist is dopamine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::972d50b5ea48a29ccdc7cbe46d8244f6
https://doi.org/10.2218/gtopdb/f20/2023.1
https://doi.org/10.2218/gtopdb/f20/2023.1
Autor:
Laureano D. Asico, Xiaoyan Wang, Pedro A. Jose, Ines Armando, Maria Paula Serrão, David K. Grandy, John E. Jones, Patrício Soares-da-Silva, Santiago Cuevas
Publikováno v:
Hypertension Research. 41:489-498
Abnormalities of the D(2)R gene (DRD2) play a role in the pathogenesis of human essential hypertension; variants of the DRD2 have been reported to be associated with hypertension. Disruption of Drd2 (D(2)(−/−)) in mice increases blood pressure an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6984353726cf09ef23ed0b7b28c9c8ee
https://doi.org/10.1038/s41440-018-0041-5
https://doi.org/10.1038/s41440-018-0041-5
Autor:
Hubert H.M. Van Tol, David R. Sibley, Jean-Charles Schwartz, Saloman Z. Langer, Kim A. Neve, John W. Kebabian, Jean-Martin Beaulieu, Arvid Carlsson, Marc G. Caron, Pierre Sokoloff, Pierre F. Spano, Olivier Civelli, Emiliana Borrelli, Maria Cristina Missale, Philip Seeman, Bernard Scatton, Raul R. Gainetdinov, Gilberto Fisone, Göran Sedvall, Stefano Espinoza, David K. Grandy
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2019
Dopamine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Dopamine Receptors [363]) are commonly divided into D1-like (D1 and D5) and D2-like (D2, D3 and D4) families, where the endogenous agonist is dopamine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b836b6969dcf52b8b5cd803be161f0be
https://doi.org/10.2218/gtopdb/f20/2019.4
https://doi.org/10.2218/gtopdb/f20/2019.4
Publikováno v:
Drug and Alcohol Dependence. 159:9-16
Background In keeping with the free-thinking tradition San Antonians are known for, the Scientific Program Committee of the Behavior, Biology and Chemistry: Translational Research in Addiction Conference chose trace amine-associated receptor 1 (TAAR1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b8c3b4fcb6e08c68c28f9eccc704126
https://doi.org/10.1016/j.drugalcdep.2015.11.014
https://doi.org/10.1016/j.drugalcdep.2015.11.014
Autor:
Joanna C. Jacob, Tamara Antonio, David K. Grandy, Juan Zhen, Aloke K. Dutta, Dana E. Selley, Maarten E. A. Reith
Publikováno v:
Neurochemical Research. 41:328-339
In elucidating the role of pharmacodynamic efficacy at D3 receptors in therapeutic effectiveness of dopamine receptor agonists, the influence of study system must be understood. Here two compounds with D3 over D2 selectivity developed in our earlier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5a194707ec5ce81213d207fdd2aa640
https://doi.org/10.1007/s11064-015-1808-6
https://doi.org/10.1007/s11064-015-1808-6
Publikováno v:
Neuropsychopharmacology. 41:971-978
Previous studies suggest dopamine (DA) D2-like receptor involvement in the reinforcing effects of food. To determine contributions of the three D2-like receptor subtypes, knockout (KO) mice completely lacking DA D2, D3, or D4 receptors (D2R, D3R, or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91aed38c43ab3a934e2212decf45793a
https://doi.org/10.1038/npp.2015.223
https://doi.org/10.1038/npp.2015.223
Autor:
Onarae V. Rice, David K. Grandy, Zehan Sarwar, Charles R. Ashby, Kareema Roushdy, Panayotis K. Thanos
Publikováno v:
Synapse. 69:356-364
The dopamine D4 receptor has been postulated to play a role in the pathophysiology of alcoholism. This study examined how varying levels of D4 expression and their associated behaviors in male and female mice correlate with future alcohol intake. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6530a7937d8bfa9041b0756aa3021a1e
https://doi.org/10.1002/syn.21822
https://doi.org/10.1002/syn.21822
Publikováno v:
Psychopharmacology. 231:3169-3177
Rationale A previous study showed that dopamine (DA) D2 receptors (D2Rs) are involved in the reinforcing effectiveness of food, but the specific involvement of DA D2Rs in choice among food reinforcers remains unclear. Objectives The current study use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d52a6d3276f22bcac363562dbcc3d94e
https://doi.org/10.1007/s00213-014-3495-4
https://doi.org/10.1007/s00213-014-3495-4
Autor:
Madeline Grandy, Edmund A. Reese, Yohei Norimatsu, David K. Grandy, Katherine L. Suchland, James R. Bunzow
Publikováno v:
Journal of Medicinal Chemistry. 57:378-390
Amphetamines are widely abused drugs that interfere with dopamine transport and storage. Recently, however, another mechanism of action was identified: stereoselective activation of the GαS protein-coupled trace amine-associated receptor 1 (TAAR1).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c4c72343119aaf4b3028c509a980ee1
https://doi.org/10.1021/jm401316v
https://doi.org/10.1021/jm401316v
Autor:
John K. Grandy
Publikováno v:
Essays in Philosophy. 15:266-278
There are many interpretations of what consciousness is. In the past decade materialist and reductionist theories have gained in popularity as many neurological correlates of consciousness have been identified experimentally. This article presents a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0490710761952f9ce281a7d947e754e4
https://doi.org/10.7710/1526-0569.1507
https://doi.org/10.7710/1526-0569.1507