Výsledky vyhledávání - "K. Gnanalingham"

Akademický článek

Notochordal and nucleus pulposus marker expression is maintained by sub-populations of adult human nucleus pulposus cells through aging and degeneration

Autor: Stephen M. Richardson, Francesca E. Ludwinski, Kanna K. Gnanalingham, Ross A. Atkinson, Anthony J. Freemont, Judith A. Hoyland

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)

Abstract The nucleus pulposus (NP) of the intervertebral disc (IVD) demonstrates substantial changes in cell and matrix composition with both ageing and degeneration. While recent transcriptomic profiling studies have helped define human NP cell phen

Externí odkaz: https://doaj.org/article/6bd7742895a34ed49e2da4e7232f0efb

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Venous thromboembolism chemical prophylaxis after endoscopic trans-sphenoidal pituitary surgery

Autor: Daniel Horner, James Kersey, Kanna K. Gnanalingham, Tara Kearney, Annabel Chadwick, Mueez Waqar, Omar N. Pathmanaban, Konstantina Karabatsou

Publikováno v: Pituitary. 25:267-274

Purpose There is no compelling outcome data or clear guidance surrounding postoperative venous thromboembolism (VTE) prophylaxis using low molecular weight heparin (chemoprophylaxis) in patients undergoing pituitary surgery. Here we describe our expe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0f2fc7e1132a5d36b35e7d08d1ca9eb
https://doi.org/10.1007/s11102-021-01195-8

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Endoscopic transsphenoidal surgery for biochemically and clinically non-functioning adenohypophyseal tumours in the elderly: experience from a single UK centre

Autor: Tara Kearney, Omar N. Pathmanaban, Federico Roncaroli, James A. Balogun, Kanna K. Gnanalingham, Konstantina Karabatsou, Andrew Edwards-Bailey, Boon Leong Quah, Hariclea Vasilopoulos

Publikováno v: Quah, B L, Edwards-Bailey, A, Gnanalingham, K, Pathmanaban, O, Vasilopoulos, H, Roncaroli, F, Kearney, T, Balogun, J & Karabatsou, K 2021, ' Endoscopic transsphenoidal surgery for biochemically and clinically non-functioning adenohypophyseal tumours in the elderly : experience from a single UK centre ', Endocrine . https://doi.org/10.1007/s12020-021-02910-y

PURPOSE: To assess and compare outcome of surgical management of non-functioning pituitary adenohypophyseal tumours in patients under 65-years, and 65-years and older at tertiary neurosurgical referral centre.METHODS: Data was retrospectively analyse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b9ae1829d563a8ec69abb2395288dee
https://doi.org/10.1007/s12020-021-02910-y

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Quantitative Magnetic Resonance-Derived Biomarkers as Predictors of Function and Histotype in Adenohypophyseal Tumours

Autor: Tara Kearney, Daniel Lewis, Kanna K. Gnanalingham, Federico Roncaroli, David Coope

Publikováno v: Neuroendocrinology. 112:276-286

Introduction: Magnetic resonance imaging (MRI) is the main modality to diagnose adenohypophyseal tumours, while biochemical assessment of pituitary hormones allows for their functional classification. In this retrospective exploratory cohort study, w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8ec5befaea1437655ef7a172a88b9b4
https://doi.org/10.1159/000516823

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Primary epithelial‐myoepithelial carcinoma of the pituitary gland

Autor: Robert Metcalf, Federico Roncaroli, Tara Kearney, Fabio Callipo, Rhianedd Ellwood-Thompson, Victoria Lavin, Rovel Colaco, Kanna K. Gnanalingham, Ibrahim Djoukhadar, Carmine Antonio Donofrio, Claire E Higham

Publikováno v: Neuropathology. 40:261-267

Primary salivary gland-like tumors of the sella are rare and often challenging to diagnose. They reportedly derive from serous and mucinous glands that remain trapped in the infundibulum during embryogenesis. We report a 68-year-old man who presented

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e5c6170dac3431d5e2b189c7ea0458f
https://doi.org/10.1111/neup.12628

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CSF rhinorrhoea after endonasal intervention to the skull base (CRANIAL) - Part 1: multicentre pilot study

Autor: Rafid Al-Mahfoudh, Sam Muquit, Simon Stapleton, Neil Donnelly, Syed Shumon, Alexandros Boukas, Duncan Henderson, Shahzada Ahmed, Ramesh Nair, Parag Sayal, Patrick McAleavey, Alex Paluzzi, Kismet Hossain-Ibrahim, Raj Bhalla, Andrew J. Martin, Hugo Layard Horsfall, Wai Cheong Soon, Mohamed Youssef, Mahmoud Kamel, Simon Cudlip, Sinan Al-Barazi, Patrick Statham, Rory J Piper, Simon Shaw, Ahmad M. S. Ali, Jonathan Shapey, Eleni Maratos, Andrew F. Alalade, Graham Dow, Omar N. Pathmanaban, Bhaskar Ram, Caroline Hayhurst, Brendan Hanna, Anastasios Giamouriadis, Angelos G. Kolias, Alireza Shoakazemi, Jane Halliday, Benjamin E. Schroeder, Mohammad Habibullah Khan, Annabel Chadwick, Nicholas Thomas, Callum M. Allison, Claire Nicholson, Catherine Gilkes, Mark Hughes, Pragnesh Bhatt, Shumail Mahmood, Kanna K. Gnanalingham, Georgios Solomou, James R. Tysome, Nigel Mendoza, Adithya Varma, Peter D. Lacy, Theodore Hirst, Danyal Z. Khan, Vikesh Patel, Paresh Naik, Benjamin Stew, Iain Robertson, Meriem Amarouche, Mohsen Javadpour, Daniel M Fountain, Neil Dorward, Christopher P. Millward, Rishi Sharma, Thomas Santarius, Anuj Bahl, Dimitris Paraskevopoulos, Alice O’Donnell, Soham Bandyopadhyay, Joan Grieve, Mohammad Saud Khan, Yasir A. Chowdhury, Showkat Mirza, Nijaguna Mathad, Daniel Murray, Elena Roman, Jonathan Pollock, P.E. Ross, Hani J. Marcus, Adam Williams, Georgios Tsermoulas, Jonathan Hempenstall, Alistair Jenkins, Richard Mannion, Ivan Cabrilo, David Bennett, Nick Phillips, Philip Weir, David Choi, Saurabh Sinha

Publikováno v: CRANIAL Consortium 2021, ' CSF Rhinorrhoea After Endonasal Intervention to the Skull Base (CRANIAL)-Part 1 : Multicenter Pilot Study ', World Neurosurgery . https://doi.org/10.1016/j.wneu.2020.12.171

Background CRANIAL (CSF Rhinorrhoea After Endonasal Intervention to the Skull Base) is a prospective multicenter observational study seeking to determine 1) the scope of skull base repair methods used and 2) corresponding rates of postoperative cereb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b82259ddcd40c76c44b0a95e25b5d3
http://hdl.handle.net/10044/1/85887

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CSF rhinorrhoea after endonasal intervention to the anterior skull base (CRANIAL): proposal for a prospective multicentre observational cohort study

Autor: Simon Cudlip, Rafid Al-Mahfoudh, Neil Donnelly, Alex Paluzzi, David Choi, Nicholas Thomas, Kismet Hossain-Ibrahim, Peter D. Lacy, Raj Bhalla, Mahmoud Kamel, Sinan Al-Barazi, Iain Robertson, Mohammad Habibullah Khan, Angelos G. Kolias, Patrick Statham, Ramesh Nair, Georgios Solomou, James R. Tysome, Adam Williams, Sam Muquit, Benjamin Stew, Daniel M Fountain, Rishi Sharma, Simon Shaw, Shahzada Ahmed, Jonathan Hempenstall, Richard Mannion, Brendan Hanna, Ivan Cabrilo, Rory J Piper, Graham Dow, Showkat Mirza, Bhavna Ramachandran, Mark Hughes, Pragnesh Bhatt, Andrew J. Martin, Kanna K. Gnanalingham, Andrew F. Alalade, Nick Phillips, Simon Stapleton, P.E. Ross, Claire Nicholson, Jane Halliday, Benjamin E. Schroeder, Parag Sayal, Dimitris Paraskevopoulos, Alice O’Donnell, Eleni Maratos, Mohsen Javadpour, Anuj Bahl, Bhaskar Ram, Anastasios Giamouriadis, Omar N. Pathmanaban, Nigel Mendoza, Hani J. Marcus, Neil Dorward, Thomas Santarius, Jonathan Pollock, Philip Weir, Saurabh Sinha, Catherine Gilkes, Joan Grieve, Vikesh Patel, Georgios Tsermoulas, Alistair Jenkins, David Bennett, Danyal Z Khan, Nijaguna Mathad, Caroline Hayhurst, Alireza Shoakazemi, Soham Bandyopadhyay

Publikováno v: Neurology and Neurosurgery Interest Group (NANSIG), British Neurosurgical Trainee Research Collaborative (BNTRC) & CRANIAL Steering Committee 2020, ' CSF rhinorrhoea after endonasal intervention to the anterior skull base (CRANIAL) : proposal for a prospective multicentre observational cohort study ', British journal of neurosurgery . https://doi.org/10.1080/02688697.2020.1795622

Background: The endonasal transsphenoidal approach (TSA) has emerged as the preferred approach in order to treat pituitary adenoma and related sellar pathologies. The recently adopted expanded endonasal approach (EEA) has improved access to the ventr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3b0bf12ea07cd0211b05bb988992b6c
https://pubmed.ncbi.nlm.nih.gov/32909855

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Value of Early Post-Operative Growth Hormone Testing in Predicting Long-Term Remission and Residual Disease after Transsphenoidal Surgery for Acromegaly

Autor: Federico Roncaroli, Yi Yuen Wang, Carmela Caputo, Peter J Trainer, Mueez Waqar, Julian R. E. Davis, Tara Kearney, A. Abou-Zeid, Claire E Higham, Kanna K. Gnanalingham

Publikováno v: Wang, Y Y, Waqar, M, Abou-Zeid, A, Kearney, T, Caputo, C, Davis, J, Trainer, P, Higham, C, Roncaroli, F & Gnanalingham, K K 2021, ' Value of early post-operative growth hormone testing in predicting long-term remission and residual disease after transsphenoidal surgery for Acromegaly ', Neuroendocrinology . https://doi.org/10.1159/000517476

Introduction: Surgical remission for acromegaly is dependent on a number of factors including tumour size, invasiveness, and surgical expertise. We studied the value of early post-operative growth hormone (GH) level as a predictor of outcome and to g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14f43377064fdf45880adc933e1eba30
https://pubmed.ncbi.nlm.nih.gov/34052822

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