Zobrazeno 1 - 10
of 267
pro vyhledávání: '"K. Ganeshaguru"'
Publikováno v:
British Journal of Haematology. 85:439-445
When monoclonal B cells from B-chronic lymphocytic leukaemia (B-CLL) patients are cultured in vitro, they die by apoptosis. Apoptotic cell death occurred in the B cells from 20/24 B-CLL patients after 26-30 h in in vitro culture, with 14.3-59.0% (mea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a714d1042ef5747addab09aaf8d4c42f
https://doi.org/10.1111/j.1365-2141.1993.tb03330.x
https://doi.org/10.1111/j.1365-2141.1993.tb03330.x
Deoxyribonucleoside triphosphate pools have been measured in nucleated bone marrow cells from normal subjects and from patients with leukaemia. The deoxyribonucleoside triphosphate (dNTP) concentrations were increased approximately 3-fold in patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06b606b7a911065ec9b8d101276cf2f6
https://doi.org/10.1159/000386065
https://doi.org/10.1159/000386065
Publikováno v:
Leukemia & Lymphoma. 11:239-248
Forty one patients with acute myeloid leukemia (AML), including 27 at presentation and 14 relapsed or resistant cases, were assessed for laboratory evidence of the MDR phenotype. Leukaemic cells from all 41 cases were studied by immunocytochemistry u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f388ad7734f3323ed25f8a25486cf771
https://doi.org/10.3109/10428199309087001
https://doi.org/10.3109/10428199309087001
Autor:
Atul Mehta, J. J. M. Van Dongen, George Janossy, Dario Campana, K. Ganeshaguru, I. L. M. Wolvers-Tettero, E. Coustan-Smith
Publikováno v:
Scopus-Elsevier
In this study five monoclonal antibodies (MoAbs) to T-cell receptor (TCR) proteins (WT31, alpha F1, beta F1, TCR delta-1 and delta TCS-1) were used to identify discrete maturative stages in 40 cases of T-cell acute lymphoblastic leukemia (T-ALL). The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::096d7a144541f148fd2dc311d9c92bbd
https://doi.org/10.1182/blood.v77.7.1546.bloodjournal7771546
https://doi.org/10.1182/blood.v77.7.1546.bloodjournal7771546
Publikováno v:
Leukemia & Lymphoma. 5:357-364
We have analysed and compared the applicability of mRNA quantitation and immunocytochemistry to the detection of the multidrug resistant gene mdr1 and its protein product P-glycoprotein (PGP) in patients with acute leukaemia. Elevated mdr1 mRNA was d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b41fdce822ad081ea8bc7acfc06d006b
https://doi.org/10.3109/10428199109067629
https://doi.org/10.3109/10428199109067629
Autor:
K. Ganeshaguru, W. C. P. de Mel, Anthony H. Goldstone, F. J. Giles, A. V. Hoffbrand, Atul Mehta
Publikováno v:
British Journal of Haematology. 74:452-456
2',5'oligoadenylate (2-5A) synthetase mRNA and enzyme levels have been studied in peripheral blood mononuclear cells from 12 patients with chronic granulocytic leukaemia (CGL), 14 with essential thrombocythaemia (ET) and nine with chronic lymphocytic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be754356344333f33a1555f35c9d771c
https://doi.org/10.1111/j.1365-2141.1990.tb06334.x
https://doi.org/10.1111/j.1365-2141.1990.tb06334.x
Publikováno v:
Oncology reports. 14(4)
The gastrin CCK2 pathway has been implicated in the development of various cancers including leukaemia. An autocrine or intracrine pathway may exist in the leukaemia cell that is involved in stimulating proliferation. We tested four leukaemia cell li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1503aa5ebb2af96f73076312b40845a
https://pubmed.ncbi.nlm.nih.gov/16142371
https://pubmed.ncbi.nlm.nih.gov/16142371
Publikováno v:
British Journal of Haematology. 90:476-478
Chromosomal abnormalities are detected by conventional cytogenetic or FISH analysis in 50% of chronic lymphocytic leukaemias (CLL). Trisomy 12 and del 13q14 account for 70% of these abnormalities. The incidence of these two abnormalities was studied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb9ec7ebf7753148f7c55a1f692f3b30
https://doi.org/10.1111/j.1365-2141.1995.tb05180.x
https://doi.org/10.1111/j.1365-2141.1995.tb05180.x
Publikováno v:
Haematologica. 88(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::950a7ee1f4b64f2c2a4b997df9c64853
https://pubmed.ncbi.nlm.nih.gov/12604426
https://pubmed.ncbi.nlm.nih.gov/12604426
Autor:
R G, Wickremasinghe, K, Ganeshaguru, D T, Jones, C, Lindsay, V J, Spanswick, J A, Hartley, M, Wadhwa, R, Thorpe, A V, Hoffbrand, H G, Prentice, A B, Mehta
Publikováno v:
British journal of haematology. 114(3)
We have studied the actions of autologous plasma on both basal and DNA damage-induced apoptosis in B-chronic lymphocytic leukaemia (B-CLL) cells. Apoptosis was quantified using morphological criteria and Western blot analysis for the apoptosis-specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d23a2422f5a7a833dfa83787ad043f22
https://pubmed.ncbi.nlm.nih.gov/11552986
https://pubmed.ncbi.nlm.nih.gov/11552986