Zobrazeno 1 - 10
of 277
pro vyhledávání: '"K. Ganapathi"'
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Aurora A kinase (AAK) involved in G2-M transition is functionally involved in centrosome maturation and maintaining an active spindle assembly checkpoint. We tested the hypothesis that in platinum-taxane resistant high grade serous ovarian cancer (HG
Externí odkaz:
https://doaj.org/article/cdaebad91e714c29be25e0047bbfb87e
Autor:
Eric J. Norris, Wendell D. Jones, Marius D. Surleac, Andrei J. Petrescu, Darla Destephanis, Qing Zhang, Issam Hamadeh, Jeffrey S. Kneisl, Chad A. Livasy, Ram N. Ganapathi, David L. Tait, Mahrukh K. Ganapathi
Publikováno v:
Gynecologic Oncology Reports, Vol 23, Iss C, Pp 41-44 (2018)
Neurofibromatosis type 1 (NF1) is caused by mutations in the NF1 gene encoding neurofibromin, which negatively regulates Ras signaling. NF1 patients have an increased risk of developing early onset breast cancer, however, the association between NF1
Externí odkaz:
https://doaj.org/article/36019dcd99444d79b87027ded525eddd
Autor:
Ram N. Ganapathi, Nury Steuerwald, Kaitlin E. Klotz, Eric J. Norris, Wendell D. Jones, Mahrukh K. Ganapathi, Jaroslaw P. Maciejewski, Yogin Patel
Publikováno v:
Leukemia & Lymphoma. 62:473-477
All trans retinoic acid (ATRA) has demonstrated curative activity in acute promyelocytic leukemia (APL), a distinct subtype of acute myeloid leukemia (AML), that is characterized by a chromosomal t...
Autor:
David L. Tait, Wendell D. Jones, Chad A. Livasy, Eric J. Norris, Mahrukh K. Ganapathi, Darla Destephanis, Ram N. Ganapathi, Qing Zhang, Ashley P. Sutker
Publikováno v:
The Journal of Pathology
High grade serous ovarian carcinoma (HGSC) without identifiable serous tubal intraepithelial carcinoma (STIC) within the fallopian tube (FT) occurs in approximately 50% of patients. The objective of this study was to use a multisite tumor sampling ap
Autor:
Ram N. Ganapathi, Mahrukh K. Ganapathi
Publikováno v:
Frontiers in Pharmacology, Vol 4 (2013)
Inhibitors of topoisomerase II (topo II) are clinically effective in the management of hematological malignancies and solid tumors. The efficacy of anti-tumor drugs targeting topo II is often limited by resistance and studies with in vitro cell cultu
Externí odkaz:
https://doaj.org/article/47060ee7b8b34779b3401391e8d639bf
Autor:
Eric J, Norris, Yogin C, Patel, Kaitlin E, Klotz, Nury, Steuerwald, Wendell D, Jones, Jaroslaw P, Maciejewski, Ram N, Ganapathi, Mahrukh K, Ganapathi
Publikováno v:
Leukemialymphoma. 62(2)
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Frontiers in Oncology
Frontiers in Oncology
Aurora A kinase (AAK) involved in G2-M transition is functionally involved in centrosome maturation and maintaining an active spindle assembly checkpoint. We tested the hypothesis that in platinum-taxane resistant high grade serous ovarian cancer (HG
Autor:
Mahrukh K. Ganapathi
Publikováno v:
Acute Phase Proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98bdbd423e2d6604947559f802e9990a
https://doi.org/10.1201/9781003068587-35
https://doi.org/10.1201/9781003068587-35
Autor:
Ram N. Ganapathi, Cheryl L. Willman, Frederick R. Appelbaum, Jerald P. Radich, John E. Godwin, Eric R. Koegle, Shannon McDonough, Megan Othus, Stephen H. Petersdorf, Anjali S. Advani, Mahrukh K. Ganapathi, Andrew P. Michelson, Alan F. List
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Anthracyclines used in the treatment of acute myelogenous leukemia (AML) inhibit the activity of the mammalian topoisomerase II (topo II) isoforms, topo II α and topo IIβ. In 230 patients with non-M3 AML who received frontline ara-C/daunorubicin we
Autor:
Susan A.J. Vaziri, Emmanuel J Tavares, Ali R Golshayan, Brian I Rini, Hakan eAydin, Ming eZhou, Linda eSercia, Laura eWood, Mahrukh K Ganapathi, Ronald M Bukowski, Ram eGanapathi
Publikováno v:
Frontiers in Oncology, Vol 2 (2012)
In sporadic clear cell renal cell carcinoma (CCRCC), the von Hippel Lindau (VHL) gene is inactivated by mutation or methylation in the majority of primary (P) tumors. Due to differing effects of wild-type (WT) and mutant (MT) VHL gene on downstream s
Externí odkaz:
https://doaj.org/article/ed11f9d27d1a4e088b609c548e081d2a