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Akademický článek

Development of a rapid, simple, and sensitive point-of-care technology platform utilizing ternary NanoLuc

Autor: Emily A. Torio, Valerie T. Ressler, Virginia A. Kincaid, Robin Hurst, Mary P. Hall, Lance P. Encell, Kristopher Zimmerman, Stuart K. Forsyth, William M. Rehrauer, Molly A. Accola, Chia-Chang Hsu, Thomas Machleidt, Melanie L. Dart

Publikováno v: Frontiers in Microbiology, Vol 13 (2022)

Point-of-care tests are highly valuable in providing fast results for medical decisions for greater flexibility in patient care. Many diagnostic tests, such as ELISAs, that are commonly used within clinical laboratory settings require trained technic

Externí odkaz: https://doaj.org/article/9343fd9d3e9b4dcaa378e95d0d22ecaf

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Akademický článek

The Effects of Engineered Aeration on Atmospheric Methane Flux From a Chesapeake Bay Tidal Tributary

Autor: Laura L. Lapham, Edward A. Hobbs, Jeremy M. Testa, Andrew Heyes, Melinda K. Forsyth, Casey Hodgkins, Curtis Szewczyk, Lora A. Harris

Publikováno v: Frontiers in Environmental Science, Vol 10 (2022)

Engineered aeration is one solution for increasing oxygen concentrations in highly eutrophic estuaries that undergo seasonal hypoxia. Although there are various designs for engineered aeration, all approaches involve either destratification of the wa

Externí odkaz: https://doaj.org/article/766b4622abf44fad8a4dcb5946dbd823

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Akademický článek

A contemporary understanding of iron metabolism in active premenopausal females

Autor: Claire E. Badenhorst, Adrienne K. Forsyth, Andrew D. Govus

Publikováno v: Frontiers in Sports and Active Living, Vol 4 (2022)

Iron metabolism research in the past decade has identified menstrual blood loss as a key contributor to the prevalence of iron deficiency in premenopausal females. The reproductive hormones estrogen and progesterone influence iron regulation and cont

Externí odkaz: https://doaj.org/article/77304fc36b024cb78766a53fd69003d5

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Akademický článek

Transcriptomic profiling of whole blood in 22q11.2 reciprocal copy number variants reveals that cell proportion highly impacts gene expression

Autor: Amy Lin, Jennifer K. Forsyth, Gil D. Hoftman, Leila Kushan-Wells, Maria Jalbrzikowski, Deepika Dokuru, Giovanni Coppola, Ania Fiksinski, Janneke Zinkstok, Jacob Vorstman, Daniel Nachun, Carrie E. Bearden

Publikováno v: Brain, Behavior, & Immunity - Health, Vol 18, Iss , Pp 100386- (2021)

22q11.2 reciprocal copy number variants (CNVs) offer a powerful quasi-experimental “reverse-genetics” paradigm to elucidate how gene dosage (i.e., deletions and duplications) disrupts the transcriptome to cause further downstream effects. Clinica

Externí odkaz: https://doaj.org/article/7bbf0d5c64de4d89987d58b825e1a27b

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Akademický článek

Cerebello-thalamo-cortical hyperconnectivity as a state-independent functional neural signature for psychosis prediction and characterization

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)

Brain function alterations in schizophrenia and other psychotic disorders remain poorly understood. Here, the authors discover that increased neural connectivity in the cerebello-thalamo-cortical circuitry predicts psychosis in those at high risk, an

Externí odkaz: https://doaj.org/article/90e889c2e50f47319e444c8a9c82d126

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Associations between physical activity and cognitive dysfunction in older companion dogs: results from the Dog Aging Project

Autor: Emily E, Bray, David A, Raichlen, Kiersten K, Forsyth, Daniel E L, Promislow, Gene E, Alexander, Evan L, MacLean, Benjamin S, Wilfond

Publikováno v: GeroScience

Canine cognitive dysfunction (CCD) is a form of dementia that shares many similarities with Alzheimer’s disease. Given that physical activity is believed to reduce risk of Alzheimer’s disease in humans, we explored the association between physica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a713287aa67105103a51e0fabfecda3
https://doi.org/10.1007/s11357-022-00655-8

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Longitudinal trajectories of cortical development in 22q11.2 copy number variants and typically developing controls

Autor: Maria Jalbrzikowski, Amy Lin, Ariana Vajdi, Vardui Grigoryan, Leila Kushan, Christopher R. K. Ching, Charles Schleifer, Rebecca A. Hayes, Stephanie A. Chu, Catherine A. Sugar, Jennifer K. Forsyth, Carrie E. Bearden

Publikováno v: Molecular psychiatry, vol 27, iss 10

Probing naturally-occurring, reciprocal genomic copy number variations (CNVs) may help us understand mechanisms that underlie deviations from typical brain development. Cross-sectional studies have identified prominent reductions in cortical surface

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9229b6d2a5b6626687efd3aa11cd1cc0
https://doi.org/10.1038/s41380-022-01681-w

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