Zobrazeno 1 - 10
of 1 537
pro vyhledávání: '"K. FitzGerald"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Interest in gene therapy medicines is intensifying as the first wave of gene-correcting drugs is now reaching patient populations. However, efficacy and safety concerns, laborious manufacturing protocols, and the high cost of the therapeutic
Externí odkaz:
https://doaj.org/article/1c8ba852bfce4937bb9eebda8b7353b5
Autor:
M. K. Fitzgerald, J. D. L. White
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Maar-diatreme volcanoes are the second-most common type on land, occurring in volcanic fields within all major tectonic environments. Their deposits typically contain an abundance of lithic fragments quarried from the substrate, and many con
Externí odkaz:
https://doaj.org/article/76a2d9b930614386a710a2761fb3c5e1
Autor:
Nuno GB Neto, Sinead A O'Rourke, Mimi Zhang, Hannah K Fitzgerald, Aisling Dunne, Michael G Monaghan
Publikováno v:
eLife, Vol 11 (2022)
In this study, we utilise fluorescence lifetime imaging of NAD(P)H-based cellular autofluorescence as a non-invasive modality to classify two contrasting states of human macrophages by proxy of their governing metabolic state. Macrophages derived fro
Externí odkaz:
https://doaj.org/article/fa72c5e814184ffa983d2f215ae305c0
The Emotional Flow Scale: Validating a Measure of Dynamic Emotional Experiences in Message Reception
Publikováno v:
Media Psychology. :1-22
Autor:
Hannah K. Fitzgerald, Sinead A. O’Rourke, Eva Desmond, Nuno G. B. Neto, Michael G. Monaghan, Miriam Tosetto, Jayne Doherty, Elizabeth J. Ryan, Glen A. Doherty, Derek P. Nolan, Jean M. Fletcher, Aisling Dunne
Publikováno v:
Antioxidants, Vol 11, Iss 1, p 164 (2022)
The extracellular parasite and causative agent of African sleeping sickness Trypanosoma brucei (T. brucei) has evolved a number of strategies to avoid immune detection in the host. One recently described mechanism involves the conversion of host-deri
Externí odkaz:
https://doaj.org/article/daea71fc4daf47e5b167422d9b5c9366
Autor:
Sinead A. O'Rourke, Nuno G.B. Neto, Eimear Devilly, Lianne C. Shanley, Hannah K. Fitzgerald, Michael G. Monaghan, Aisling Dunne
Publikováno v:
Atherosclerosis. 352:35-45
Metabolic reprogramming of innate immune cells is emerging as a key player in the progression of a number of chronic diseases, including atherosclerosis, where high rates of glycolysis correlate with plaque instability. This study aimed to investigat
Autor:
Nicole K. Campbell, David G. Williams, Hannah K. Fitzgerald, Paul J. Barry, Clare C. Cunningham, Derek P. Nolan, Aisling Dunne
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
African trypanosomes, such as Trypanosoma brucei (T. brucei), are protozoan parasites of the mammalian vasculature and central nervous system that are best known for causing fatal human sleeping sickness. As exclusively extracellular parasites, trypa
Externí odkaz:
https://doaj.org/article/c8debaae71514200868c058fdb41129d
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Polyphenols are important immunonutrients which have been investigated in the context of inflammatory and autoimmune disease due to their significant immunosuppressive properties. However, the mechanism of action of many polyphenols is unclear, parti
Externí odkaz:
https://doaj.org/article/d08dba1d9786459f818b8db98e160f55
Autor:
Henry J. Thompson, Tymofiy Lutsiv, John N. McGinley, Vanessa K. Fitzgerald, Elizabeth S. Neil
Publikováno v:
Nutrients; Volume 15; Issue 9; Pages: 2015
Obesity prevention is stated as a simple objective in the public health guidelines of most countries: avoid adult weight gain. However, the success of the global population in accomplishing this goal is limited as reflected in the persisting pandemic
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