Zobrazeno 1 - 10
of 252
pro vyhledávání: '"K. F. Turchin"'
Autor:
Patrick J. Brennan, Valeriya S. Velezheva, Irina N. Fedorova, K. F. Turchin, Alexander Yu. Lepyoshkin, Alexander S. Peregudov
Publikováno v:
Journal of Heterocyclic Chemistry. 50:225-236
We report on two approaches for the synthesis of new 2-amino-3-cyano/alkoxycarbonyl-8H-thieno[2,3-b]indoles 5 and another one for the synthesis of 2-N,N-dialkylamino-3-cyano/aryl-8H-thieno[2,3-b]indoles 16, based either on acetylindoxyl 1 and (1-acet
Publikováno v:
Pharmaceutical Chemistry Journal. 43:588-591
Publikováno v:
Pharmaceutical Chemistry Journal. 41:670-675
It is shown that the drug teraphthal should be considered as a mixture of the octasodium salt of cobalt(II) 2,3,9,10,16,17,23,24-octacarboxyphthalocyanine (OCPC) and its oxidation product (component A) with the octasodium salt of OCPC and products fr
Autor:
K. A. Lyssenko, Valeriya S. Velezheva, Ivan V. Stankevich, K. F. Turchin, E. G. Gal'pern, A. Yu. Lepeshkin
Publikováno v:
Russian Chemical Bulletin. 56:1447-1455
Based on the results of studies of the deuterium exchange and dehydration of 4-hydroxy-Δ2-thiazolines and 2-R-4-acetyl-8b-hydroxy-3a,8b-dihydro-4H-thiazolo[5,4-b]indoles containing the α-methylene (methine) unit at the C(2) atom, the mechanism of d
Publikováno v:
Russian Chemical Bulletin. 56:1441-1446
In reactions with some α-halo ketones (3-bromo-1,1,1-trifluoropropan-2-one, 1-acetyl-2-bromoindolin-3-one, and α-bromoacetophenone), thioacetamide and a series of thioamides of aromatic and heteroaromatic acids are transformed into 4-hydroxy-Δ2-th
Publikováno v:
Pharmaceutical Chemistry Journal. 39:216-221
A new modification of the accq-tag-HPLC technique for the rapid determination of L-proline and γ-aminobutyric acid (GABA) in a culture medium is proposed. The concentration of L-isoleucine added to the culture medium is shown to influence the accumu
Autor:
Fedor I. Zubkov, K. F. Turchin, Alexey V. Varlamov, Roman S. Borisov, Ekaterina V. Boltukhina
Publikováno v:
Tetrahedron. 61:4099-4113
Acylation of substituted 4-(furyl-2)-4-arylaminobut-1-enes with maleic anhydride provided 2-allyl-6-carboxy-4-oxo-3-aza-10-oxatricyclo[5.2.1.01,5]dec-8-enes in high yield under mild reaction conditions. The Diels–Alder adducts are formed via an ini
Publikováno v:
Tetrahedron. 60:8455-8463
Acylation of 4-α-furyl-4- N -benzylaminobut-1-enes with maleic anhydride gave 4-oxo-3-aza-10-oxatricyclo[5.2.1.0 1,5 ]dec-8-ene-6-carboxylic acid via amide formation followed by intramolecular Diels–Alder reaction of furan (IMDAF). The cycloadditi
Publikováno v:
Chemistry of Heterocyclic Compounds. 40:1097-1105
We obtained perhydro-1,2,3-oxathiazine 2,2-dioxides by cyclization of 4-N-benzylamino-4-tetramethylene(phenyl-, methylphenyl-, dimethyl)but-1-enes in conc. H2SO4 at 25°C. When treated with an alcoholic solution of base, the oxathiazines are converte
Autor:
Alexey V. Varlamov, K. F. Turchin, Roman S. Borisov, A. A. Safronova, Fedor I. Zubkov, Eugeniya V. Nikitina
Publikováno v:
Russian Chemical Bulletin. 53:860-872
The intramolecular Diels—Alder reaction of readily accessible 4-substituted 4-(N-furfuryl)aminobut-1-enes was studied and a new one-step method was developed for the synthesis of 6,8a-epoxy-1,2,3,4,4a,5,6,8a-octahydroisoquinoline (3-aza-11-oxatricy