Zobrazeno 1 - 10
of 34
pro vyhledávání: '"K. F. Soike"'
Publikováno v:
Comparative medicine. 50(2)
Spontaneous viral encephalitis is rare in the baboon; yet, during a 13-month period (1993-1994), eight juvenile baboons (Papio cynocephalus spp.) developed acute, progressive nonsuppurative meningoencephalomyelitis caused by an unknown agent. Clinica
Publikováno v:
Laboratory animal science. 48(1)
Simian varicella virus (SVV) causes sporadic epizootics of a varicella-like disease in nonhuman primates. Rapid diagnosis of simian varicella is critical in controlling epizootics. A polymerase chain reaction (PCR)-based diagnostic assay for detectio
Publikováno v:
Pharmaceutical research. 11(6)
The bioavailability of PMEA from three oral formulations of the prodrug bis(POM)-PMEA has been evaluated in fasted male cynomolgus monkeys. The formulations examined included a hydroxypropyl-beta-cyclodextrin (HPBCD) complex, a PEG based cosolvent so
Publikováno v:
Advances in experimental medicine and biology. 342
Two separate studies are described in this report. First, 5 Owl monkeys were inoculated intracerebrally (IC) with coronavirus JHM OMP1; this virus isolate was cultured from the brain of an animal inoculated with uncloned MHV JHM. Two of the animals b
Publikováno v:
Ophthalmic surgery. 23(12)
Two preparations of silicone gels were evaluated as long-term vitreous substitutes in the vitrectomized and lensectomized eyes of primates. Both preparations were injected in liquid form and polymerized in the vitreous cavity. There was no toxic effe
Publikováno v:
Ophthalmic surgery. 23(12)
We investigated the toxicity of single doses of intravitreally administered interferon alpha-2a in albino rabbits. Following injection of interferon in doses of 40,000, 80,000, 160,000, 320,000, and 640,000 IU/0.1 mL, no significant histologic change
Publikováno v:
Veterinary pathology. 29(6)
Publikováno v:
Laboratory animal science. 42(3)
Approximately 80 baboon deaths were caused by encephalomyocarditis virus (EMCV) infection in a 3060 member research and production colony. The epizootic extended over a 9-month period and occurred in baboons ranging from 1 day to 22 years of age. Acu
Autor:
A N, Dueland, J R, Martin, M E, Devlin, M, Wellish, R, Mahalingam, R, Cohrs, K F, Soike, D H, Gilden
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 66(6)
Five African green monkeys inoculated intratracheally with 7.5 x 10(3) to 1.4 x 10(5) plaque-forming units of simian varicella virus (SVV) were subjected to clinical, laboratory, pathologic, and virologic analyses to study the pathogenesis of acute v
Publikováno v:
Ophthalmic surgery. 22(11)
Six African green monkeys (six eyes) underwent vitrectomy and vitreous replacement with Vitreon (perfluorophenanthrene) or Vitreon plus silicone. A seventh animal served as a control. Vitreon alone and in combination remained optically clear and allo