Zobrazeno 1 - 10
of 342
pro vyhledávání: '"K. Esser A"'
Autor:
Hannah Ochner, Sven Szilagyi, Moritz Edte, Tim K. Esser, Stephan Rauschenbach, Luigi Malavolti, Klaus Kern
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Conformational changes play a key role in the biological function of many proteins, thereby sustaining a multitude of processes essential to life. Thus, the imaging of the conformational space of proteins exhibiting such conformational chang
Externí odkaz:
https://doaj.org/article/8ff1be818e9641b7b1fefe41039a5949
Autor:
Francesca Fontana, Alison K Esser, Christopher Egbulefu, Partha Karmakar, Xinming Su, John S Allen, Yalin Xu, Jennifer L Davis, Ariel Gabay, Jingyu Xiang, Kristin A Kwakwa, Brad Manion, Suzanne Bakewell, Shunqiang Li, Haeseong Park, Gregory M Lanza, Samuel Achilefu, Katherine N Weilbaecher
Publikováno v:
PLoS ONE, Vol 18, Iss 12, p e0293700 (2023)
BackgroundConjugation of transferrin (Tf) to imaging or nanotherapeutic agents is a promising strategy to target breast cancer. Since the efficacy of these biomaterials often depends on the overexpression of the targeted receptor, we set out to surve
Externí odkaz:
https://doaj.org/article/900e008d55c449cf9eddf7877d941a4a
Autor:
Laura K. Esser, Vittorio Branchi, Sonia Leonardelli, Natalie Pelusi, Adrian G. Simon, Niklas Klümper, Jörg Ellinger, Stefan Hauser, Maria A. Gonzalez-Carmona, Manuel Ritter, Glen Kristiansen, Hubert Schorle, Michael Hölzel, Marieta I. Toma
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Clear cell renal cell carcinoma (ccRCC) is the most common renal cancer accounting for 80% of all renal cancers as well as the majority of renal cancer-associated deaths. During the last decade, the treatment paradigm for ccRCC has radically changed.
Externí odkaz:
https://doaj.org/article/97d1d568f6ac4813aad29aec50665885
Autor:
Paul Fremdling, Tim K. Esser, Bodhisattwa Saha, Alexander A. Makarov, Kyle L. Fort, Maria Reinhardt-Szyba, Joseph Gault, Stephan Rauschenbach
Electrospray ion-beam deposition (ES-IBD) is a versatile tool to study the structure and reactivity of molecules from small metal clusters to large protein assemblies. It brings molecules gently into the gas phase, where they can be accurately manipu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bc51efcbc8275aff109c76fa927b656
https://doi.org/10.1021/acsnano.2c04831
https://doi.org/10.1021/acsnano.2c04831
Autor:
Katherine N. Weilbaecher, Gregory M. Lanza, Deborah J. Veis, Samuel Achilefu, Vijay Sharma, James A.J. Fitzpatrick, Suzanne J. Bakewell, Christopher A. Maher, Sheila A. Stewart, Jothilingam Sivapackiam, Ha X. Dang, Kristen Pagliai, Elizabeth Cordell, Alison K. Esser, Jingyu Xiang, Francesca Fontana, Michael H. Ross, Kristin A. Kwakwa, Yalin Xu, Jennifer L. Davis, Xinming Su, Gregory C. Fox
Evaluation of cellular response to mTORC1 inhibition, BLI analysis of visceral metastases in PyMT-BO1 tumor-bearing mice receiving combination therapies, and αvβ3-NP-RAPA toxicity studies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c1ebfd46c55529ed738e69d53e03c4d
https://doi.org/10.1158/1535-7163.22521939
https://doi.org/10.1158/1535-7163.22521939
Autor:
Katherine N. Weilbaecher, Klaus Dembowsky, Rebecca L. Aft, Johann Zimmermann, Michael Bauer, Gary D. Luker, Eric Chevalier, Gérald Tuffin, Barbara Romagnoli, Foluso O. Ademuyiwa, Timothy Pluard, Kathryn E. Luker, Chidananda Mudalagiriyappa, Garry J. Douglas, Alison K. Esser, Sarah R. Amend, Xinming Su, Francesca Fontana, Michelle A. Hurchla, Jingyu Xiang
Supplemental Figure 1-2. Supplemental Figure 1: Pharmacology of POL5551; Supplemental Figure 2: Correlation of CXCR4 expression in primary tumor with survival in patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35bdd674a20e9eff353c1fd084861560
https://doi.org/10.1158/1535-7163.22507255.v1
https://doi.org/10.1158/1535-7163.22507255.v1
Autor:
Katherine N. Weilbaecher, Gregory M. Lanza, Deborah J. Veis, Samuel Achilefu, Vijay Sharma, James A.J. Fitzpatrick, Suzanne J. Bakewell, Christopher A. Maher, Sheila A. Stewart, Jothilingam Sivapackiam, Ha X. Dang, Kristen Pagliai, Elizabeth Cordell, Alison K. Esser, Jingyu Xiang, Francesca Fontana, Michael H. Ross, Kristin A. Kwakwa, Yalin Xu, Jennifer L. Davis, Xinming Su, Gregory C. Fox
Breast cancer bone metastases are common and incurable. Tumoral integrin β3 (β3) expression is induced through interaction with the bone microenvironment. Although β3 is known to promote bone colonization, its functional role during therapy of est
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e9742668dcb390c0c8c105e42940932
https://doi.org/10.1158/1535-7163.c.6543234.v1
https://doi.org/10.1158/1535-7163.c.6543234.v1
Autor:
Katherine N. Weilbaecher, Klaus Dembowsky, Rebecca L. Aft, Johann Zimmermann, Michael Bauer, Gary D. Luker, Eric Chevalier, Gérald Tuffin, Barbara Romagnoli, Foluso O. Ademuyiwa, Timothy Pluard, Kathryn E. Luker, Chidananda Mudalagiriyappa, Garry J. Douglas, Alison K. Esser, Sarah R. Amend, Xinming Su, Francesca Fontana, Michelle A. Hurchla, Jingyu Xiang
Supplemental Figure 5. Eribulin dose ranging study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cea9ef473838bff804e8ac90d64e2bd
https://doi.org/10.1158/1535-7163.22507246.v1
https://doi.org/10.1158/1535-7163.22507246.v1
Autor:
Katherine N. Weilbaecher, Klaus Dembowsky, Rebecca L. Aft, Johann Zimmermann, Michael Bauer, Gary D. Luker, Eric Chevalier, Gérald Tuffin, Barbara Romagnoli, Foluso O. Ademuyiwa, Timothy Pluard, Kathryn E. Luker, Chidananda Mudalagiriyappa, Garry J. Douglas, Alison K. Esser, Sarah R. Amend, Xinming Su, Francesca Fontana, Michelle A. Hurchla, Jingyu Xiang
Supplemental Figure 3. Gaussia luciferase complementation imaging model and scratch migration assay with AMD3100.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::302a4c36bf35925a1c265d0af7bfef62
https://doi.org/10.1158/1535-7163.22507252.v1
https://doi.org/10.1158/1535-7163.22507252.v1
Autor:
Katherine N. Weilbaecher, Klaus Dembowsky, Rebecca L. Aft, Johann Zimmermann, Michael Bauer, Gary D. Luker, Eric Chevalier, Gérald Tuffin, Barbara Romagnoli, Foluso O. Ademuyiwa, Timothy Pluard, Kathryn E. Luker, Chidananda Mudalagiriyappa, Garry J. Douglas, Alison K. Esser, Sarah R. Amend, Xinming Su, Francesca Fontana, Michelle A. Hurchla, Jingyu Xiang
Supplemental Figure 4. MDA-MB-231 primary tumor weight and liver metastases data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18264d11afd52e2afa1cde8936b1c0a5
https://doi.org/10.1158/1535-7163.22507249.v1
https://doi.org/10.1158/1535-7163.22507249.v1