Zobrazeno 1 - 7
of 7
pro vyhledávání: '"K. Elaine Hubbard"'
Autor:
Clinton F. Stewart, Mohamed A. Elmeliegy, Christopher M. Waters, John C. Panetta, Henry G. Wynn, Michael Tagen, K. Elaine Hubbard, Angel M. Carcaboso, Jun Shen
Supplementary Figure 1 from Compartment-Specific Roles of ATP-Binding Cassette Transporters Define Differential Topotecan Distribution in Brain Parenchyma and Cerebrospinal Fluid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6527618c5992a051c1b0d3b2db50410b
https://doi.org/10.1158/0008-5472.22379405
https://doi.org/10.1158/0008-5472.22379405
Autor:
Clinton F. Stewart, Mohamed A. Elmeliegy, Christopher M. Waters, John C. Panetta, Henry G. Wynn, Michael Tagen, K. Elaine Hubbard, Angel M. Carcaboso, Jun Shen
Supplementary Methods from Compartment-Specific Roles of ATP-Binding Cassette Transporters Define Differential Topotecan Distribution in Brain Parenchyma and Cerebrospinal Fluid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a6603501e96e764b75af479a69f8cf1
https://doi.org/10.1158/0008-5472.22379402.v1
https://doi.org/10.1158/0008-5472.22379402.v1
Autor:
Clinton F. Stewart, Mohamed A. Elmeliegy, Christopher M. Waters, John C. Panetta, Henry G. Wynn, Michael Tagen, K. Elaine Hubbard, Angel M. Carcaboso, Jun Shen
Topotecan is a substrate of the ATP-binding cassette transporters P-glycoprotein (P-gp/MDR1) and breast cancer resistance protein (BCRP). To define the role of these transporters in topotecan penetration into the ventricular cerebrospinal fluid (vCSF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a01f7502778cc3a7f5eeb186b863ffc5
https://doi.org/10.1158/0008-5472.c.6499241.v1
https://doi.org/10.1158/0008-5472.c.6499241.v1
Autor:
Christopher M. Waters, Clinton F. Stewart, John C. Panetta, Mohamed A. Elmeliegy, Michael Tagen, Jun Shen, Henry G. Wynn, K. Elaine Hubbard, Angel M. Carcaboso
Publikováno v:
Cancer Research. 69:5885-5892
Topotecan is a substrate of the ATP-binding cassette transporters P-glycoprotein (P-gp/MDR1) and breast cancer resistance protein (BCRP). To define the role of these transporters in topotecan penetration into the ventricular cerebrospinal fluid (vCSF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ddf74adbd4270e122a1f077be3d919f
https://doi.org/10.1158/0008-5472.can-09-0700
https://doi.org/10.1158/0008-5472.can-09-0700
Autor:
Laura Miller, Charles H. Fraga, John C. Panetta, Paula Schaiquevich, Feng Bai, Clinton F. Stewart, K. Elaine Hubbard
Individualization of topotecan dosing reduces inter-patient variability in topotecan exposure, presumably reducing toxicity and increasing efficacy. However, logistical limitations (e.g. requirement for plasma, intensive bedside plasma processing) ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63776d03bca7a4eb0ee0a4b64dfa73b4
https://europepmc.org/articles/PMC2914494/
https://europepmc.org/articles/PMC2914494/
Autor:
Clinton F. Stewart, Charles H. Fraga, Thandranese S. Owens, Michael Tagen, K. Elaine Hubbard, Amy Wells
Publikováno v:
Biomedical Chromatography.
A method to rapidly measure dopamine (DA), dihydroxyindolphenylacetic acid, homovanillic acid, serotonin (5-HT) and 5-hydroxyindoleacetic acid concentrations in cerebrospinal fluid (CSF) has not yet been reported. A rapid, sensitive, and specific HPL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7334a4171996293a428afb1a93809c1a
https://doi.org/10.1002/bmc.1338
https://doi.org/10.1002/bmc.1338
Autor:
Nikolaus Hagedorn, John C. Panetta, Clinton F. Stewart, Christopher M. Waters, Charles H. Fraga, Yanli Zhuang, K. Elaine Hubbard
Publikováno v:
Cancer research. 66(23)
A potential strategy to increase the efficacy of topotecan to treat central nervous system (CNS) malignancies is modulation of the activity of ATP-binding cassette (ABC) transporters at the blood-brain and blood-cerebrospinal fluid barriers to enhanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d91947859321cffb2a18d0d2aafe442
https://pubmed.ncbi.nlm.nih.gov/17145877
https://pubmed.ncbi.nlm.nih.gov/17145877