Zobrazeno 1 - 10
of 11
pro vyhledávání: '"K. E. Lauhala"'
Publikováno v:
International journal of radiation biology. 64(4)
Female, young adult, Wistar rats were given a single inhalation exposure to a submicron sized aerosol of high-fired 239PuO2 and observed during their lifespan for primary lung tumours. Rats were distributed among sham-control (n = 1052) and exposed (
Publikováno v:
Health physics. 64(5)
Spatial-temporal dose-distribution patterns in the lung continually change following inhalation of radionuclides. Lung clearance, microdosimetry, and radiation dose were examined in female Wistar rats exposed to high-fired 169Yb2O3-239PuO2 aerosols.
Publikováno v:
International Journal of Radiation Biology. 54:115-121
SummaryAggregation of inhaled 239PuO2 particles in the pulmonary region of the lung may be required for promotion of pulmonary carcinogenesis in rats. Female Wistar rats were exposed to an aerosol of 239PuO2 and their lungs examined by scanning elect
Publikováno v:
Health physics. 56(3)
We have applied the scanning electron microscope (SEM) to obtain autoradiographs of particles of /sup 239/PuO/sub 2/ deposited in rat lung. The technique was used to obtain quantitative information on the clearance rates of particles from the alveoli
Publikováno v:
Scanning microscopy. 3(3)
Pulmonary aggregation of inhaled 239PuO2 particles leads to a cellular evolution of focal inflammation, fibrosis, epithelial dysplasia and lung tumor formation. Female Wistar rats were exposed to an aerosol of high-fired 239PuO2 (initial lung burden,
Publikováno v:
Experimental lung research. 15(5)
The goal of this study is to show the relationship of inhaled Pu particle distribution and alveolar-bronchiolar target-cell response with respect to the formation of pulmonary carcinoma. The proliferation of type 2 alveolar epithelium and nonciliated
Publikováno v:
Scanning microscopy. 2(3)
Scanning electron microscopic (SEM) autoradiography of the lung is being used to determine the distribution of inhaled, alpha particle-emitting, plutonium dioxide particles. SEM autoradiography provides high visual impact views of alpha activity. Par
Publikováno v:
Radiation research. 116(3)
Promotion of lung tumor formation from inhaled 239PuO2 in rats may be associated with aggregation of plutonium particles near bronchioles. The relationship of plutonium particle aggregation in the lung and the development of lung tumors after inhalat
Publikováno v:
Proceedings, annual meeting, Electron Microscopy Society of America. 47:922-923
The role of the alveolar epithelium in removal of deposited particles from the alveolar air space has not been well defined. Type II cells, although in close proximity to particles, do not participate in the phagocytosis of particles. How ever, a var
Autor:
R. L. Buschbom, K. E. McDonald, E. S. Gilbert, K. E. Lauhala, J. F. Park, R. E. Weller, C.L. Sanders
Publikováno v:
Health Physics. 57:331