Zobrazeno 1 - 10
of 60
pro vyhledávání: '"K. Douville"'
Autor:
Hans Verstraelen, Mark Mitchnick, B. Variano, J. van Roey, Paul Coplan, K. Douville, Marleen Temmerman, Steven Weyers, L. van Bortel, Joseph Romano, Zeda F. Rosenberg
Publikováno v:
AIDS Research and Human Retroviruses. 25:483-488
Vaginal delivery of 200 mg or 25 mg dapivirine from intravaginal rings (IVRs) was evaluated over a 7-day period in two phase 1 safety trials (IPM001 and IPM008, respectively) in a total of 25 healthy women 19 to 46 years of age. The IVR was generally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fa6b59acf0a50aa3cf23c923e49bcfa
https://doi.org/10.1089/aid.2008.0184
https://doi.org/10.1089/aid.2008.0184
Autor:
Zeda F. Rosenberg, Jeremy Nuttall, Saul Walker, Pamela Norick, K. Douville, Caroline Galbreath
Publikováno v:
Therapy. 4:725-730
Diseases largely confined to the developing world are under-researched in part because of the limited commercial potential for products used in these settings. The need for an alternative model has led to the establishment of product-development part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58914371cd1e29defc77f34dd8814840
https://doi.org/10.2217/14750708.4.6.725
https://doi.org/10.2217/14750708.4.6.725
Autor:
Joseph Romano, Timothy J. McCormick, Roger L. Schnaare, Thomas R Moench, Feirong Kang, Jill L. Schwartz, Robert W. Buckheit, Gina Cohl, K. Douville, Gustavo F. Doncel, Karen M. Watson, Mark G. Lewis, Deborah Tien
Publikováno v:
AIDS Research and Human Retroviruses. 21:845-853
The development of vaginal microbicides for the prevention of sexual transmission of HIV is becoming an increasingly important strategy in the battle against the AIDS epidemic. Several first generation microbicide candidates are entering Phase III ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04758ee22e18607f1f45f2ce1d83b18d
https://doi.org/10.1089/aid.2005.21.845
https://doi.org/10.1089/aid.2005.21.845
Publikováno v:
Contraception. 66:365-368
Despite a significant worldwide need for effective microbicides to reduce sexually transmitted diseases (STD) and HIV transmission, none is currently available. C31G, a surface active anti-infective agent that is active in vitro against bacterial and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::156d9fba4961f4b37a5cbf6598093f50
https://doi.org/10.1016/s0010-7824(02)00389-x
https://doi.org/10.1016/s0010-7824(02)00389-x
Autor:
K X Gao, Stanley C. Froehner, Neal R. Kramarcy, Robert Sealock, A A Murnane, K Douville, M H Butler
Publikováno v:
The Journal of Cell Biology
Two high-affinity mAbs were prepared against Torpedo dystrophin, an electric organ protein that is closely similar to human dystrophin, the gene product of the Duchenne muscular dystrophy locus. The antibodies were used to localize dystrophin relativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4008881368c69a09fce64259747f298c
http://europepmc.org/articles/PMC2289019
http://europepmc.org/articles/PMC2289019
Autor:
K. Douville, Annalene Nel, Jeremy Nuttall, Saul Walker, William Heyward, Joseph Romano, Caroline Galbreath, Mark Mitchnick, Zeda F. Rosenberg
Publikováno v:
Infectious disease clinics of North America. 21(1)
Topical microbicides are self-administered products for prevention of HIV transmission, and they present one of the most promising strategies for combating the HIV-AIDS epidemic. The development of microbicides is a long and complicated process, with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17ad08a6aa05c5cd7bdcc5e9bbb9c1bc
https://pubmed.ncbi.nlm.nih.gov/17502237
https://pubmed.ncbi.nlm.nih.gov/17502237
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 12(2)
Transforming growth factor beta (TGF-beta) is a multifunctional cytokine capable of regulating diverse cellular processes. In this study we investigated the effect of autocrine TGF-beta signaling on tumor necrosis factor (TNF) alpha-induced cell deat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9d2973bf65d30559ab8aee563341dc2a
https://pubmed.ncbi.nlm.nih.gov/11243465
https://pubmed.ncbi.nlm.nih.gov/11243465
Publikováno v:
The Journal of biological chemistry. 269(29)
Escherichia coli preprotein translocase consists of the peripheral membrane protein SecA and the integral membrane domain SecY/E. SecY/E, whether isolated chromatographically or by immunoprecipitation, was found to be complex of three polypeptides, S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa175966030fc99ada16aaa8ce3e5d8f
https://pubmed.ncbi.nlm.nih.gov/8034620
https://pubmed.ncbi.nlm.nih.gov/8034620
Publikováno v:
The Journal of biological chemistry. 267(9)
Dystrophin was purified by immunoaffinity chromatography from detergent-solubilized Torpedo electric organ postsynaptic membranes using monoclonal antibodies. A major doublet of proteins at Mr 58,000 and minor proteins at Mr 87,000, Mr 45,000, and Mr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8304860b1d79b3bd1fa31beca0da54f0
https://pubmed.ncbi.nlm.nih.gov/1556129
https://pubmed.ncbi.nlm.nih.gov/1556129
Autor:
J. Romano, B. Variano, P. Coplan, J. Van Roey, K. Douville, Z. Rosenberg, M. Temmerman, H. Verstraelen, L. Van Bortel, S. Weyers, M. Mitchnick
Publikováno v:
AIDS Research & Human Retroviruses; May2009, Vol. 25 Issue 5, p483-488, 6p