Zobrazeno 1 - 10
of 61
pro vyhledávání: '"K. D. Zamba"'
Autor:
Chandra K. Maharjan, Shaikamjad Umesalma, Courtney A. Kaemmer, Viviane P. Muniz, Casey Bauchle, Sarah L. Mott, K. D. Zamba, Patrick Breheny, Mariah R. Leidinger, Benjamin W. Darbro, Samuel B. Stephens, David K. Meyerholz, Dawn E. Quelle
Publikováno v:
Biomedicines, Vol 9, Iss 6, p 633 (2021)
Pancreatic neuroendocrine tumors (pNETs) are difficult-to-treat neoplasms whose incidence is rising. Greater understanding of pNET pathogenesis is needed to identify new biomarkers and targets for improved therapy. RABL6A, a novel oncogenic GTPase, i
Externí odkaz:
https://doaj.org/article/0be6e6f7c96143f89dfeb782deeff057
Autor:
Courtney A. Kaemmer, Shaikamjad Umesalma, Chandra K. Maharjan, Devon L. Moose, Goutham Narla, Sarah L. Mott, Gideon K. D. Zamba, Patrick Breheny, Benjamin W. Darbro, Andrew M. Bellizzi, Michael D. Henry, Dawn E. Quelle
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Pancreatic neuroendocrine neoplasms (pNENs) are slow growing cancers of increasing incidence that lack effective treatments once they become metastatic. Unfortunately, nearly half of pNEN patients present with metastatic liver tumors at diag
Externí odkaz:
https://doaj.org/article/ae2055035fc14c58a5dbf133596a14d9
Autor:
David L. Bushnell, M. Sue O'Dorisio, K D Zamba, Thomas M. O'Dorisio, Janet H Pollard, Mark T. Madsen, Yusuf Menda
Publikováno v:
Cancer Biother Radiopharm
Background: Histone deacetylase (HDAC) inhibitors have been shown in preclinical studies to upregulate norepinephrine transporters in neuroblastoma and pheochromocytoma, and somatostatin receptors in pulmonary carcinoid, small cell lung cancer, and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34f4a5b97864f0c96d98458241bda7f3
https://doi.org/10.1089/cbr.2020.4633
https://doi.org/10.1089/cbr.2020.4633
Autor:
Stephen A. Graves, Yusuf Menda, David L. Bushnell, Thomas M. O'Dorisio, Kellie L. Bodeker, M. Sue O'Dorisio, Gideon K. D. Zamba, Mark T. Madsen
Publikováno v:
Journal of Nuclear Medicine. 62:1274-1277
Peptide receptor radionuclide therapy (PRRT) is an effective treatment for metastatic neuroendocrine tumors. Delivering a sufficient tumor radiation dose remains challenging because of critical-organ dose limitations. Adding 131I-metaiodobenzylguanid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6f4fd0e157b9387e198ae85a2d7dc57
https://doi.org/10.2967/jnumed.120.254987
https://doi.org/10.2967/jnumed.120.254987
Autor:
K. D. Zamba, Akim Adekpedjou
Publikováno v:
Sequential Analysis. 38:318-341
This article provides a goodness-of-fit test for the distribution function or the survival function in a recurrent event setting, when the inter-event time parametric structure F(·;θ) is estimated ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4886c468d3eac62653f031b0ad614db
https://doi.org/10.1080/07474946.2019.1648920
https://doi.org/10.1080/07474946.2019.1648920
RABL6A inhibits tumor-suppressive PP2A/AKT signaling to drive pancreatic neuroendocrine tumor growth
Autor:
Jussara Hagen, Timothy Ginader, Abbey L. Perl, Terry A. Braun, Gideon K. D. Zamba, Bart J. Brown, Dawn E. Quelle, James R. Howe, Jacqueline A. Reilly, Goutham Narla, Benjamin W. Darbro, Fenghuang Zhan, Angela M. Schab, Aaron T. Scott, Blake L. Letney, Jordan L. Kohlmeyer, Courtney A. Kaemmer, Shaikamjad Umesalma, Joseph S. Dillon, David K. Meyerholz, Mariah R. Leidinger, Stefan Strack, Thomas M. O'Dorisio, Andrew M. Bellizzi, Agshin F. Taghiyev, Frederick W. Quelle, Nitija Tiwari, Ronald A. Merrill, Ryan M. Sheehy
Publikováno v:
Journal of Clinical Investigation. 129:1641-1653
Hyperactivated AKT/mTOR signaling is a hallmark of pancreatic neuroendocrine tumors (PNETs). Drugs targeting this pathway are used clinically, but tumor resistance invariably develops. A better understanding of factors regulating AKT/mTOR signaling a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::232bebbf58142beac4d6bf84a1f8bff8
https://doi.org/10.1172/jci123049
https://doi.org/10.1172/jci123049
Autor:
K. D. Zamba, Panagiotis Tsiamyrtzis
This article develops a detection framework using Bayesian philosophy by adaptation of Shiryaev's and Roberts' methodology. We propose two unifying versions directly applicable in industrial proces...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7ba4f74551dcf9ede316f39a8490b15
http://hdl.handle.net/11311/1175134
http://hdl.handle.net/11311/1175134
Autor:
Jeffrey D. Dawson, Gideon K. D. Zamba
Publikováno v:
Leadership in Statistics and Data Science ISBN: 9783030600594
Establishing and maintaining student pipelines is an important and challenging endeavor. We discuss how to create an inclusive environment, make connections to build pipelines, and provide continuing maintenance. The emphasis is on pipelines between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1661f10331d18a06de746b554ef8b10d
https://doi.org/10.1007/978-3-030-60060-0_15
https://doi.org/10.1007/978-3-030-60060-0_15
Autor:
Andrew M. Bellizzi, Shaikamjad Umesalma, Gideon K. D. Zamba, Michael D. Henry, Patrick Breheny, Chandra K. Maharjan, Sarah L. Mott, Courtney A. Kaemmer, Goutham Narla, Benjamin W. Darbro, Devon L. Moose, Dawn E. Quelle
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Pancreatic neuroendocrine neoplasms (pNENs) are slow growing cancers of increasing incidence that lack effective treatments once they become metastatic. Unfortunately, nearly half of pNEN patients present with metastatic liver tumors at diagnosis and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d253c72c41829c13114d51b4198559d
https://pubmed.ncbi.nlm.nih.gov/33986468
https://pubmed.ncbi.nlm.nih.gov/33986468
Autor:
David L, Bushnell, Kellie L, Bodeker, Thomas M, O'Dorisio, Mark T, Madsen, Yusuf, Menda, Stephen, Graves, Gideon K D, Zamba, M Sue, O'Dorisio
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 62(9)
Peptide receptor radionuclide therapy (PRRT) is an effective treatment for metastatic neuroendocrine tumors. Delivering a sufficient tumor radiation dose remains challenging because of critical-organ dose limitations. Adding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2f7a1f7d007f335ddb7d827fd7ee2d27
https://pubmed.ncbi.nlm.nih.gov/33517327
https://pubmed.ncbi.nlm.nih.gov/33517327