Zobrazeno 1 - 10
of 22
pro vyhledávání: '"K. D. Somers"'
Autor:
R P, Ciavarra, K D, Somers, R R, Brown, W F, Glass, P J, Consolvo, G L, Wright, P F, Schellhammer
Publikováno v:
Cancer research. 60(8)
We assessed the in vivo efficacy of Flt3-ligand (Flt3-L) treatment in C57BL/6 mice bearing a well-established MHC class I-negative prostate carcinoma TRAMP-C1. Flt3-L immunotherapy was initiated approximately 30 days after tumor inoculation, a time w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2c772e6331e7435fad3651b0b8b4ef43
https://pubmed.ncbi.nlm.nih.gov/10786663
https://pubmed.ncbi.nlm.nih.gov/10786663
Autor:
Y, Wu, A J, Palad, W J, Wasilenko, P F, Blackmore, W A, Pincus, G L, Schechter, J R, Spoonster, E C, Kohn, K D, Somers
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 3(11)
Local invasion and lymph node metastasis are correlated with a decreased overall survival in head and neck cancer patients and warrant new strategies to intervene in the metastatic cascade. One approach is to focus on the intracellular signaling path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f6a5c39598ba9e61a228c08a795c027d
https://pubmed.ncbi.nlm.nih.gov/9815580
https://pubmed.ncbi.nlm.nih.gov/9815580
Autor:
J, Gresham, P, Margiotta, A J, Palad, K D, Somers, P F, Blackmore, G L, Wright, P F, Schellhammer, W J, Wasilenko
Publikováno v:
International journal of cancer. 77(6)
Autocrine growth factors for the epidermal growth factor receptor (EGFR) have been identified in prostate tumors, implicating a role for EGFR in the progression of prostate cancer. To investigate early signaling mechanisms used by the EGFR in prostat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bd556e17e5a86fa673fefa1839b99823
https://pubmed.ncbi.nlm.nih.gov/9714065
https://pubmed.ncbi.nlm.nih.gov/9714065
Autor:
W J, Wasilenko, J, Cooper, A J, Palad, K D, Somers, P F, Blackmore, J S, Rhim, G L, Wright, P F, Schellhammer
Publikováno v:
The Prostate. 30(3)
Cellular calcium is an important second messenger for growth regulation. We sought to identify potentially important receptors on prostate tumor cells by screening over 20 agonists for their ability to increase intracellular free calcium ([Ca2+]i) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f6cac7d3569edc546ef6f3f669a63727
https://pubmed.ncbi.nlm.nih.gov/9122041
https://pubmed.ncbi.nlm.nih.gov/9122041
Autor:
K D, Somers, D M, Dawson
Publikováno v:
The Journal of urology. 157(1)
Peyronie's disease is a pathological fibrosis characterized by excessive deposition of collagen in the plaque. Although the etiology of Peyronie's disease is unknown, trauma has been hypothesized as the inciting event. In an effort to obtain more ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7bf551a349bf3c4befc7ea47db1222c8
https://pubmed.ncbi.nlm.nih.gov/8976287
https://pubmed.ncbi.nlm.nih.gov/8976287
Autor:
W J, Wasilenko, A J, Palad, K D, Somers, P F, Blackmore, E C, Kohn, J S, Rhim, G L, Wright, P F, Schellhammer
Publikováno v:
International journal of cancer. 68(2)
Aberrant cellular signaling is a central feature of malignant cells and a potential target for anti-cancer therapy. Carboxyamido-triazole (CAI) is a calcium influx inhibitor that alters calcium-sensitive signal transduction pathways and suppresses th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a7e5b596dac78c149d9d867d7e18ca15
https://pubmed.ncbi.nlm.nih.gov/8900438
https://pubmed.ncbi.nlm.nih.gov/8900438
Publikováno v:
Oncogene. 12(1)
Amplification of chromosome 11q13 DNA sequences is detected in approximately 30% of primary head and neck squamous cell carcinomas (HNSCC). The amplified region includes genes for cyclin D1, hst-1, int-2, and more recently, ems-1. Ems-1 encodes an 80
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::06b5f41be4bfe6e440f2c10f93aeb176
https://pubmed.ncbi.nlm.nih.gov/8552396
https://pubmed.ncbi.nlm.nih.gov/8552396
Publikováno v:
Cancer research. 52(21)
Squamous cell carcinomas of the head and neck (SCCHN) are associated strongly with the use of tobacco and alcohol, but little is known about the molecular pathogenesis of these tumors. In the present study, we analyzed SCCHN for mutations in the tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3c302c20bd161d136b85098fb2ccba2f
https://pubmed.ncbi.nlm.nih.gov/1394225
https://pubmed.ncbi.nlm.nih.gov/1394225
Autor:
K D, Somers, G L, Schechter
Publikováno v:
Otolaryngologic clinics of North America. 25(5)
Mutations of the ras gene family appear to be an uncommon genetic alteration in SCCHN. A common region of DNA amplification on chromosome 11q13 has been identified in SCCHN. A cluster of proto-oncogenes (int-2, hst-1, bcl-1, prad-1) has been localize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e8eca78e3cbe37271c8953c4b0d6d212
https://pubmed.ncbi.nlm.nih.gov/1408191
https://pubmed.ncbi.nlm.nih.gov/1408191