Zobrazeno 1 - 10
of 97
pro vyhledávání: '"K. D. Praliev"'
Autor:
M. K. Amirkulova, D. M. Kadyrova, T. M. Seilkhanov, S. S. Zhumakova, V. K. Yu, E. M. Satpaeva, A. E. Malmakova, T. K. Iskakova, K. D. Praliev, A. Yu. Ten
Publikováno v:
Pharmaceutical Chemistry Journal. 54:1209-1214
The influence of the nature of the acyl (propionyl and benzoyl) moiety and the piperidine ring C4 substituent on the activity of several alkynylpiperidine derivatives was studied. The presence of an alkyl (hexyl) radical on the triple bond of the pip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e5bee5b60ca3b5dff00d9ad6103a723
https://doi.org/10.1007/s11094-021-02345-9
https://doi.org/10.1007/s11094-021-02345-9
Publikováno v:
Pharmaceutical Chemistry Journal. 54:582-587
Simultaneous Mannich condensation of 1-(3-methoxypropyl)piperidone-4 with paraformaldehyde and 1-(2-pyridinoethyl)amine yielded 3-(3methoxypropyl)-7-[2-(pyridin-2-yl)ethyl]-3,7-diazabicyclo[3.3.1]nonan-9-one, which was reduced to the corresponding bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e4b9d32b6f4e4bb50d94072bdf21fd3
https://doi.org/10.1007/s11094-020-02243-6
https://doi.org/10.1007/s11094-020-02243-6
Publikováno v:
Chemistry of Natural Compounds. 55:622-625
Products were obtained from acylation of 1,2,4-trihydroxy-9,10-anthraquinone (purpurin) by saturated cyclic carboxylic acid chlorides. The compositions and structures of the monosubstituted compounds were confirmed by elemental analysis and IR and PM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::743daad67c8e2ff2f490a16c53820e78
https://doi.org/10.1007/s10600-019-02763-y
https://doi.org/10.1007/s10600-019-02763-y
Autor:
T. K. Iskakova, L. A. Nazarenko, O. T. Seilkhanov, K. D. Praliev, T. M. Seilkhanov, S. S. Zhumakova, T. G. Bimurzayeva
Publikováno v:
Russian Journal of General Chemistry. 87:270-275
4-Acyloxy-4-(cyclopropylethynyl)-1-(2-ethoxyethyl)piperidines have been synthesized by reaction of 1-(2-ethoxyethyl)piperidin-4-one with cyclopropylacetylene and subsequent acylation of intermediate 4-(cyclopropylethynyl)piperidin-4-ol. The resulting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::735feb14126338c6659ff484af66f4bf
https://doi.org/10.1134/s1070363217020190
https://doi.org/10.1134/s1070363217020190
Autor:
V. T. Panyushkin, R. A. Sharipov, V. K. Yu, V. A. Volynkin, K. S. Sharapov, K. D. Praliev, U. S. Kemel’bekov
Publikováno v:
Journal of Inclusion Phenomena and Macrocyclic Chemistry. 87:141-148
Inclusion complex of 4-acetoxy-1-(2-ethoxyethyl)-4-phenylpiperidine with β-cyclodextrin was synthesized. Composition (1:2) and the structure of the complex were confirmed by NMR spectroscopy and thermal analysis. The results of pharmacological studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57c578db8f9b49a70df34eee942d9c43
https://doi.org/10.1007/s10847-016-0685-1
https://doi.org/10.1007/s10847-016-0685-1
Autor:
K. D. Praliev, A. A. Abzhapparov, T. N. Zharkinbekov, T. M. Seilkhanov, T. K. Iskakova, N. N. Poplavskii, O. T. Seilkhanov, L. A. Nazarenko
Publikováno v:
Russian Journal of General Chemistry. 86:110-115
A comparative analysis of 1H and 13C NMR spectra of 1-(2-ethoxyethyl)-4-(pentyn-1-yl)-4-hydroxypiperidine, 1-(2-ethoxyethyl)-4-(pentyn-1-yl)-4-benzoyloxypiperidine oxalate and their inclusion complexes with β-cyclodextrin was performed. The differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71d7b66e6f66dbee652d8915c1b8c08f
https://doi.org/10.1134/s1070363216010199
https://doi.org/10.1134/s1070363216010199
Publikováno v:
Pharmaceutical Chemistry Journal. 50:600-602
Results from studies of the local anesthetic activity of LAS-54 [4-(benzoyloxy)-3-butoxypiperidinium chloride] (synthesized at the Laboratory of the Chemistry of Synthetic and Natural Drugs, Bekturov Institute of Chemical Sciences) in combination wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed8cdf4fe1e1f73ef31a8f54f63b56fc
https://doi.org/10.1007/s11094-016-1498-7
https://doi.org/10.1007/s11094-016-1498-7
Autor:
V V, Goncharukl, A L, Buben, O A, Borisenok, V I, Kozlovskii, I M, Pun'ko, V P, Vdovichenko, K D, Praliev
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 79(11)
The work was aimed at assessing in vivo the analgesic properties of ten decahydroquinoline derivatives (pharmacologically active substances, PAS) and deter- mining the role of opioid receptors in mechanism of their action. Among the derivatives studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5f580444f8cfc56b83173b4248e3dc35
https://pubmed.ncbi.nlm.nih.gov/29791103
https://pubmed.ncbi.nlm.nih.gov/29791103
Publikováno v:
Pharmaceutical Chemistry Journal. 49:292-295
Mannich condensation was used to synthesize new bispidinones, Wolff-Kishner reduction of which produced the corresponding bispidanes. 1H NMR spectroscopy studies showed that these existed in the double chair conformation. The myelostimulatory activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b03b6e0fd0a64283ebf22e295467e28
https://doi.org/10.1007/s11094-015-1272-2
https://doi.org/10.1007/s11094-015-1272-2
Autor:
A. A. Abzhappov, L. A. Nazarenko, N. N. Poplavskii, T. N. Zharkinbekov, T. K. Iskakova, K. D. Praliev, O. T. Seilkhanov, T. M. Seilkhanov
Publikováno v:
Russian Journal of General Chemistry. 85:1098-1102
Structures of 7-[2-(morpholin-4-yl)ethyl]-3-(2-ethoxyethyl)-3,7-diazabicyclo[3.3.1]nonane and its inclusion complexes with α-, β-, and γ-cyclodextrins have been studied by 1H, 13C, COSY, and HMQC NMR spectroscopy. The complexes are formed via ente
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36fa7e417003b8f4cfe23963c8d83e87
https://doi.org/10.1134/s1070363215050175
https://doi.org/10.1134/s1070363215050175