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Factors influencing the antibody response to vaccination against rabies

Autor: V, Jakel, M, König, K, Cussler, K, Hanschmann, H-J, Thiel

Publikováno v: Developments in biologicals. 131

Preventive vaccination against rabies virus is a highly effective method for preventing rabies in humans and animals. For travel purposes, vaccination of domestic carnivores is obligatory. In addition, some countries require testing for neutralizing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ad64a3eee4241d28463c407bf6b7ae07
https://pubmed.ncbi.nlm.nih.gov/18634505

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Development of a cell culture assay for the quantitative determination of vaccination-induced antibodies in rabbit sera against Clostridium perfringens epsilon toxin and Clostridium novyi alpha toxin

Autor: K. Cussler, Frank Schulze, Ingrid Hänel, Roland Diller, Erika Borrmann

Publikováno v: Veterinary microbiology. 114(1-2)

Cell culture assays are possible alternatives to replace in vivo neutralization tests currently required for potency testing of clostridial vaccines. Cell culture assays based on the MDCK cell line and the Vero cell line which are sensitive to the Cl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35209ec0f5fef791bd363b9fa9c44de8
https://pubmed.ncbi.nlm.nih.gov/16361070

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Potency testing of inactivated erysipelas vaccines by ELISA--influence of the adjuvant on antibody development

Autor: U, Rosskopf-Streicher, S, Johannes, K, Cussler

Publikováno v: Developments in biologicals. 111

The humoral immune response after vaccination may be greatly influenced by the type of adjuvant used. In this study we investigated the influence of three different adjuvants on the serological response in laboratory mice after immunisation with comm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c82d5bd1b5f6c3487b03e76ad56253d5
https://pubmed.ncbi.nlm.nih.gov/12678236

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[The importance of allergic skin test with Johnin, antibody ELISA, cultural fecal test as well as vaccination for the sanitation of three chronically paratuberculosis-infected dairy herds in Rhineland-Palatinate]

Autor: W, Klawonn, K, Cussler, K G, Dräger, H, Gyra, H, Köhler, K, Zimmer, R G, Hess

Publikováno v: DTW. Deutsche tierarztliche Wochenschrift. 109(12)

Three chronically paratuberculosis infected herds were tested for six years twice a year (intradermal Johnin test, antibody ELISA (IDEXX Corp.), microbial culture) according to a sanitary program. Culling of shedding animals and vaccination of calves

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8d4e13bd8c9c45684668562d8ddfc1d3
https://pubmed.ncbi.nlm.nih.gov/12596564

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[Progress in the replacement of animal experiments in the quality control of clostridial vaccines]

Autor: K, Cussler, E, Borrmann, E, Werner

Publikováno v: DTW. Deutsche tierarztliche Wochenschrift. 109(4)

Animal experiments still play a central role in the quality control of vaccines. Generally, performance of these experiments is provided by law and laid down in the European Pharmacopoeia. Classical vaccines, the efficacy of which is calculated in In

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b846d9258c93c8e669b9976b54baf745
https://pubmed.ncbi.nlm.nih.gov/11998369

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Collaborative study for the establishment of erysipelas ELISA coating antigen. European Biological Reference Preparation batch no. 1

Autor: K, Cussler, U, Rosskopf-Streicher, P, Volkers, C, Milne

Publikováno v: Pharmeuropa. Special issue biologicals. 2001(1)

The development and validation of suitable alternatives for the replacement of in vivo challenge testing in the evaluation of vaccines is an important goal for national authorities and manufacturers involved in the assessment of quality, safety and e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::42a6c3d8b16ba094751ab3fc5708a13f
https://pubmed.ncbi.nlm.nih.gov/11705102

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[Clinical endpoints during rabies vaccine control tests]

Autor: J, Hartinger, T, Folz, K, Cussler

Publikováno v: ALTEX. 18(1)

All warm-blooded animals, including humans, are susceptible to rabies. The infection with the virus leads inevitably to the death of the recipient. Vaccines and anti-serums are at present the only possibility to prevent rabies infections in the human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7c616fa3f8432928e54a6ca01219fa86
https://pubmed.ncbi.nlm.nih.gov/11248849

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[100 years of erysipelas prophylaxis: significance and reduction of animal experiments]

Autor: K, Cussler, E, Balks

Publikováno v: ALTEX. 18(1)

The history of erysipelas prophylaxis began in 1882 when Pasteur first discovered the attenuating effect of rabbit passages on the erysipelas bacterium. Ten years later, the German veterinarian Lorenz demonstrated the protecting effect of erysipelas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f09a436c6a6f03a0620baec4cbe0f900
https://pubmed.ncbi.nlm.nih.gov/11248847

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