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Akademický článek
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Autor:
K M, Szauter, A, Ordas, R M, Laxer, E, Pope, D, Wherrett, B, Alman, M, Mink, C D, Boyd, K, Csiszar, A, Hinek
Publikováno v:
The British journal of dermatology. 163(5)
Clinical evaluation of a young woman with subcutaneous fibrotic nodules, progressive distal joint contractures and marfanoid stature revealed a previously unrecognized fibrotic disorder characterized by several unique phenotypic features and some fea
Publikováno v:
Verhandlungen der Deutschen Gesellschaft fur Pathologie. 91
Various microsatellite and CGH studies in prostate cancer identify deletions on the short arm of chromosome 8 especially at band 8p21-22 searching for unknown putative tumor suppressor genes. By means of microsatellite markers several candidate genes
Publikováno v:
Ciba Foundation Symposium 192-The Molecular Biology and Pathology of Elastic Tissues
Key aspects of the biosynthesis and catalytic specificity of lysyl oxidase (LO) have been explored. Oxidation of peptidyl lysine in synthetic oligopeptides is markedly sensitive to the presence of vicinal dicarboxylic ami/no acid residues. Optimal ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33e3e7667fb765a75914f259034a9fc8
https://doi.org/10.1002/9780470514771.ch6
https://doi.org/10.1002/9780470514771.ch6
Autor:
K, Csiszar
Publikováno v:
Progress in nucleic acid research and molecular biology. 70
Lysyl oxidase (LOX), a copper-containing amine oxidase, belongs to a heterogeneous family of enzymes that oxidize primary amine substrates to reactive aldehydes. LOX has been traditionally known for one function, the extracellular catalysis of lysine
Autor:
Sandra Y. Yamamoto, K. Csiszar, C. Jourdan-Lesaux, S. Hein, Gillian D. Bryant-Greenwood, K. Okazaki
Publikováno v:
Placenta. 22(1)
The cross-linking of the connective tissues in the fetal membranes and placenta is important for their tensile strength and elasticity. We have studied the expression of lysyl oxidase (LOX) because it is the classical enzyme responsible for the cross
Publikováno v:
Journal of molecular endocrinology. 23(3)
Relaxins are known endocrine and autocrine/paracrine hormones that play a major role in reproduction. In the human there are two relaxin genes, H1 and H2 which share 90% sequence homology within their coding region. The biological and evolutionary si
Publikováno v:
Neurourology and urodynamics. 18(1)
The elasticity of tissues subjected to repeated deformation is provided by the presence of elastic fibers in the extracellular matrix (ECM). The most abundant component of elastic fibers is elastin, whose soluble precursor is tropoelastin. To establi
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 78(2)
Lysyl oxidase (LO) initiates the first step in the crosslinking of collagens and elastin and has also been shown to function as a tumor suppressor. The purpose of the present work was to determine whether the products of a newly described LO-like gen