Zobrazeno 1 - 10
of 53
pro vyhledávání: '"K. Crowshaw"'
Publikováno v:
Tetrahedron Letters. 5:2307-2311
Publikováno v:
Biochemical Journal. 105:1251-1260
Rabbit kidney medulla (10kg.) was homogenized in 5mm-disodium hydrogen phosphate and deproteinized with ethanol, and the concentrated supernatant solution was extracted at pH8 with light petroleum and at pH2 with chloroform. The acidic lipids present
Autor:
A.K. Banerjee, K.A.J. Stuttle, G. L. Watkins, Caton Michael P L, M.A. Heazell, E.C.J. Coffee, T.S. Burton, K. Crowshaw, B.J. Broughton, A.J. Christmas
Publikováno v:
Prostaglandins. 16(4)
The synthesis and gastrointestinal pharmacology of some 11-deoxyprostaglandin E1 analogues are described with results analysed for selectivity from side effects. 11-Deoxygenation reduced potency relative to PGE2 but, as has been reported for natural
Autor:
M. P. L. CATON, K. CROWSHAW
Publikováno v:
Chemischer Informationsdienst. 10
Publikováno v:
Federation proceedings. 33(1)
Autor:
K, Crowshaw
Publikováno v:
Agents and actions. Supplements. (6)
The most important renal side effect of non-steroidal anti-inflammatory therapy in man is analgesic nephropathy. One possible mechanism for this effect is inhibition of renal prostaglandin synthesis. However, an understanding of the regional biosynth
Autor:
K. Crowshaw
Publikováno v:
Side-Effects of Anti-Inflammatory Drugs ISBN: 9789401097772
I will first of all briefly describe the glomerular and interstitial disease induced by a variety of NSAIDs. I will then proceed to outline the eicosanoids synthesized by human kidney and try to relate the formation or inhibition of these eicosanoids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14f66d50f7496c3c9eabd19fecd7b36f
https://doi.org/10.1007/978-94-010-9775-8_39
https://doi.org/10.1007/978-94-010-9775-8_39
Autor:
M.A. Heazell, G.C. Ivers-Read, A.J. Christmas, K. Crowshaw, L.C. Saunders, A.K. Banerjee, D. Wyatt
Publikováno v:
Life sciences. 35(25)
MB 28,767 [(+/-)11-deoxy-16-phenoxy-omega-tetranor PGE1] and 16, 16'-dimethyl PGE2 methylester (DMPG) were compared for their effects on gastric acid secretion (GAS) and gastric ulceration (GU), employing various laboratory models. In anaesthetised r
Autor:
C.J. Hardy, K.A.J. Stuttle, T. Parker, A.K. Banerjee, E.C.J. Coffee, L.C. Saunders, M.N. Palfreyman, T.S. Burton, Caton Michael P L, K. Crowshaw, A.J. Christman, M.A. Heazell, B.J. Broughton
Publikováno v:
Prostaglandins. 22(2)
( + )-11-Deoxy-16-phenoxy-17,18,19,20-tetranor-prostaglandin E 1 is a highly potent and selective anti-ulcer agent. Analogues of this compound have been synthesized and structure-activity relationships are reported.
Autor:
K. Crowshaw
Publikováno v:
Nephrotoxicity in the experimental and clinical situation ISBN: 9789401080125
The biosynthetic capacity of the mammalian kidney to produce prostaglandins is exceeded only by the seminal vesicles. Although the medulla is the major site of synthesis in the kidney, an appreciable and physiologically important synthesis also occur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41c6b96358e0c1121c18a9690b532f06
https://doi.org/10.1007/978-94-009-3367-5_11
https://doi.org/10.1007/978-94-009-3367-5_11