Zobrazeno 1 - 10 of 13 pro vyhledávání: '"K. C. Jacob"'
1
Akademický článek
Pirfenidone increases IL-10 and improves acute pancreatitis in multiple clinically relevant murine models
Autor: Ejas Palathingal Bava, John George, Mohammad Tarique, Srikanth Iyer, Preeti Sahay, Beatriz Gomez Aguilar, Dujon B. Edwards, Bhuwan Giri, Vrishketan Sethi, Tejeshwar Jain, Prateek Sharma, Utpreksha Vaish, Harrys K. C. Jacob, Anthony Ferrantella, Craig L. Maynard, Ashok K. Saluja, Rajinder K. Dawra, Vikas Dudeja
Publikováno v: JCI Insight, Vol 7, Iss 2 (2022)
Despite decades of research, there is no specific therapy for acute pancreatitis (AP). In the current study, we have evaluated the efficacy of pirfenidone, an antiinflammatory and antifibrotic agent that is approved by the FDA for treatment of idiopa
Externí odkaz: https://doaj.org/article/5a67edc6225d42e6a846bf7637ca2d15
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2
Akademický článek
The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence.
Autor: Anne-Marie Hansen, Raghothama Chaerkady, Jyoti Sharma, J Javier Díaz-Mejía, Nidhi Tyagi, Santosh Renuse, Harrys K C Jacob, Sneha M Pinto, Nandini A Sahasrabuddhe, Min-Sik Kim, Bernard Delanghe, Narayanaswamy Srinivasan, Andrew Emili, James B Kaper, Akhilesh Pandey
Publikováno v: PLoS Pathogens, Vol 9, Iss 6, p e1003403 (2013)
While phosphotyrosine modification is an established regulatory mechanism in eukaryotes, it is less well characterized in bacteria due to low prevalence. To gain insight into the extent and biological importance of tyrosine phosphorylation in Escheri
Externí odkaz: https://doaj.org/article/c699f682d7b649178d84fe149316c4c5
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5
Genetic Validation of Cell Proliferation via Ras-Independent Activation of the Raf/Mek/Erk Pathway
Autor: Carmen G, Lechuga, Lucía, Simón-Carrasco, Harrys K C, Jacob, Matthias, Drosten
Publikováno v: Methods in molecular biology (Clifton, N.J.). 1487
Signaling transmitted by the Ras family of small GTPases (H-, N-, and K-Ras) is essential for proliferation of mouse embryonic fibroblasts (MEFs). However, constitutive activation of the downstream Raf/Mek/Erk pathway can bypass the requirement for R
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::42799c2f9069cfcca879257e8abed7ce
https://pubmed.ncbi.nlm.nih.gov/27924574
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6
VARIATIONS OF SOME PLASMA COMPONENTS AFTER CLOSED FRACTURES
Autor: K C Jacob, O N Nagi, C R Nair, A L Annamalai, S K Lal
Publikováno v: The Journal of Trauma: Injury, Infection, and Critical Care. 16:206-211
1) Variations in the serum concentrations of total proteins and the electrophoretic fractions, glycoprotein, mucoprotein, fibrinogen, erythrocyte sedimentation rate, calcium, phosphorus, alkaline, and acid phosphatases were analyzed until the 30th da
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c51721642b9ff11da1517e5cbb6ce1
https://doi.org/10.1097/00005373-197603000-00005
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7
The Determination of Phendimetrazine and Phenmetrazine in Biological Fluids and in Dosage Forms
Autor: M. K. Masih, S. Z. Masih, J. L. McHan, G. Long, K. C. Jacob
Publikováno v: Drug Development and Industrial Pharmacy. 8:203-213
A highly sensitive gas chromatographic assay was developed for the simultaneous determination of phendimetrazine and its N-demethylated metabolite, phenmetrazine. The analytical procedure proved adaptable for the determination of these drugs in dosag
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::400f37e7e9057df6a99c31faa3b3dcc5
https://doi.org/10.3109/03639048209022098
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