Zobrazeno 1 - 10
of 932
pro vyhledávání: '"K. C. Cooper"'
Autor:
Daniel J. Hurst, David K. C. Cooper
Publikováno v:
Health Care Science, Vol 3, Iss 2, Pp 124-130 (2024)
Abstract Over the past several decades, significant scientific progress in xenotransplantation has brought the field to the threshold of clinical trials. In the past 3 years in the United States, experimental pig kidney and heart xenotransplantation
Externí odkaz:
https://doaj.org/article/234fa11f0f3f429191fdc9ca9e7f6ced
Autor:
David K. C. Cooper, Emanuele Cozzi
Publikováno v:
Transplant International, Vol 37 (2024)
Externí odkaz:
https://doaj.org/article/b404246baeb74ffa9cad90cc6c7d77a4
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
An estimated 1.5 million Americans suffer from Type I diabetes mellitus, and its incidence is increasing worldwide. Islet allotransplantation offers a treatment, but the availability of deceased human donor pancreases is limited. The transplantation
Externí odkaz:
https://doaj.org/article/84c69ac459bb42eeb785198b33e29052
Autor:
Kevin J. Lopez, John Paul Spence, Wei Li, Wenjun Zhang, Barry Wei, Arthur A. Cross-Najafi, James R. Butler, David K. C. Cooper, Burcin Ekser, Ping Li
Publikováno v:
Cells, Vol 12, Iss 22, p 2587 (2023)
Natural killer (NK) cells play a vital role in xenotransplantation rejection. One approach to induce NK cell immune tolerance is to prevent the NK cell-mediated direct killing of porcine cells by targeting the interaction of the activating receptor N
Externí odkaz:
https://doaj.org/article/f194ae4d408145179c6a8b98c224a0d0
Autor:
Ping Li, Julia R. Walsh, Kevin Lopez, Abdulkadir Isidan, Wenjun Zhang, Angela M. Chen, William C. Goggins, Nancy G. Higgins, Jianyun Liu, Randy R. Brutkiewicz, Lester J. Smith, Hidetaka Hara, David K. C. Cooper, Burcin Ekser
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Xenotransplantation (cross-species transplantation) using genetically-engineered pig organs offers a potential solution to address persistent organ shortage. Current evaluation of porcine genetic modifications is to monitor the nonhuman prim
Externí odkaz:
https://doaj.org/article/3ae22fee438c45fa9103891970992214
Autor:
Mohamed H. Bikhet, Christophe Hansen‐Estruch, Mariyam Javed, Dalis E. Collins, Jeremy B. Foote, David Ayares, Hidetaka Hara, David K. C. Cooper
Publikováno v:
Immunity, Inflammation and Disease, Vol 10, Iss 3, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/db2b297ec26844509ff1debb7b247733
Autor:
Tao Li, Hao Feng, Jiaxiang Du, Qiangbing Xia, David K. C. Cooper, Hongtao Jiang, Songzhe He, Dengke Pan, Gang Chen, Yi Wang
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Kidney xenotransplantation is expected to contribute to resolving the shortage of kidneys from deceased human donors. Although progress in experimental life-supporting pig renal xenotransplantation has been encouraging, there are still issues to be c
Externí odkaz:
https://doaj.org/article/3b72855c557a4d639d96ca8b9d62cce9
Autor:
Guoqiang Zhang, Hayato Iwase, Qi Li, Takayuki Yamamoto, Abhijit Jagdale, Mohamed B. Ezzelarab, David Ayares, David K. C. Cooper, Hidetaka Hara, Gangcheng Wang
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundIn pig-to-baboon transplantation models, there is increasing evidence of systemic inflammation in xenograft recipients (SIXR) associated with pig xenograft failure. We evaluated the relationship between systemic inflammatory factors and pig
Externí odkaz:
https://doaj.org/article/65bd35fe7edb40d497ed49815fdff73f
Autor:
Hanchao Gao, Mengtao Cao, Pengfei Chen, David K. C. Cooper, Yanli Zhao, Ling Wei, Jia Xu, Zhiming Cai, Changchun Zeng, Shaodong Luan, Lisha Mou
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-15 (2019)
Abstract Background The major limitation of organ transplantation is the shortage of available organs. Xenotransplantation is considered to be an effective way to resolve the problem. Immune rejection is a major hurdle for the successful survival of
Externí odkaz:
https://doaj.org/article/21927013cf84479b9fca6559c3f26731
Publikováno v:
Journal of Inflammation, Vol 16, Iss 1, Pp 1-16 (2019)
Abstract There is increasing evidence of a sustained state of systemic inflammation after pig-to-nonhuman primate (NHP) xenotransplantation (that has been termed systemic inflammation in xenograft recipients [SIXR]). Increases in inflammatory markers
Externí odkaz:
https://doaj.org/article/79fc7a6cc60c4abf9cde721ef4378b76