Fcγ receptors directly mediate cartilage, but not bone, destruction in murine antigen-induced arthritis: uncoupling of cartilage damage from bone erosion and joint inflammation

Autor: Wim B. van den Berg, Lilyanne C. Grevers, Annet W. Sloetjes, Birgit Oppers, Teun J. de Vries, Peter L E M van Lent, K. C. A. M. Nabbe, E Lubberts, Sjef Verbeek, Arjen B. Blom

Publikováno v: Arthritis and Rheumatism, 54, 3868-77
Arthritis and Rheumatism, 54(12), 3868-3877. John Wiley & Sons Inc.
Arthritis and Rheumatism, 54(12), 3868-3877. John Wiley and Sons Inc.
Arthritis and Rheumatism, 54, 12, pp. 3868-77
van Lent, P L, Grevers, L, Lubberts, E, de Vries, T J, Nabbe, K C, Verbeek, S, Oppers, B, Sloetjes, A, Blom, A B & van den Berg, W B 2006, ' Fcγ receptors directly mediate cartilage, but not bone, destruction in murine antigen-induced arthritis: uncoupling of cartilage damage from bone erosion and joint inflammation ', Arthritis and Rheumatism, vol. 54, no. 12, pp. 3868-3877 . https://doi.org/10.1002/art.22253

Contains fulltext : 49336.pdf (Publisher’s version ) (Closed access) OBJECTIVE: To determine the relationship between synovial inflammation and the concomitant occurrence of cartilage and bone erosion during conditions of variable inflammation usin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1f29177c5f8e4968d4452b63c04b44f
https://hdl.handle.net/11245/1.264968

FcγRI Up-Regulation Induced by Local Adenoviral-Mediated Interferon-γ Production Aggravates Chondrocyte Death during Immune Complex-Mediated Arthritis

Autor: K. C. A. M. Nabbe, Peter L E M van Lent, A.E.M. Holthuysen, Jay K. Kolls, Wim B. van den Berg, Sjef Verbeek

Publikováno v: American Journal of Pathology, 163, 743-52
American Journal of Pathology, 163, 2, pp. 743-52

Item does not contain fulltext Using various FcgammaR-deficient mice, we have obtained suggestive evidence that FcgammaRI on macrophages is responsible for severe cartilage destruction during arthritis mediated by immune complexes (ICs). This role of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d873b40a2f8582153e1b07dcf060b77b
https://doi.org/10.1016/s0002-9440(10)63701-7

Safety of glucocorticoids can be improved by lower yet still effective dosages of liposomal steroid formulations in murine antigen-induced arthritis: comparison of prednisolone with budesonide

Autor: Gert Storm, Fred C.G.J. Sweep, G.J. Pesman, Jolanda M. van den Hoven, K. C. A. M. Nabbe, Wouter Hofkens, Peter L. E. M. van Lent, Wim B. van den Berg

Publikováno v: International Journal of Pharmaceutics, 416, 2, pp. 493-8
International Journal of Pharmaceutics, 416, 493-8

Contains fulltext : 97335.pdf (Publisher’s version ) (Closed access) The goal of this study was to compare the effects of liposomal and free glucocorticoid formulations on joint inflammation and activity of the hypothalamic-pituitary-adrenal (HPA)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ed5b827af541561da6513d28f5c02a5
https://pubmed.ncbi.nlm.nih.gov/21382459

Dendritic cells from patients with rheumatoid arthritis lack the interleukin 13 mediated increase of Fc gamma RII expression, which has clear functional consequences

Autor: W.B. van den Berg, K. C. A. M. Nabbe, P.L.E.M. van Lent, A W T van Lieshout, Trdj Radstake, Mieke F. Roelofs, Mark H. Wenink, A Oosterlaar, Pilar Barrera

Publikováno v: Annals of the Rheumatic Diseases, 64, 1737-43
Annals of the Rheumatic Diseases, 64, 12, pp. 1737-43

Contains fulltext : 48417.pdf (Publisher’s version ) (Closed access) BACKGROUND: Dendritic cell (DC) function is largely tailored by Fc gamma receptors (Fc gamma R) and is critical for every immune response. OBJECTIVE: To compare interleukin (IL) 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a685f06c87f7ee31b98e8c25b7e8b1f8
https://pubmed.ncbi.nlm.nih.gov/15878907

Crucial role of synovial lining macrophages in the promotion of transforming growth factor beta-mediated osteophyte formation

Autor: N. van Rooijen, Arjen B. Blom, K. C. A. M. Nabbe, Elly L. Vitters, A.E.M. Holthuysen, P.M. van der Kraan, P.L.E.M. van Lent, W.B. van den Berg, Ruben L. Smeets

Publikováno v: Arthritis and Rheumatism, 50, 1, pp. 103-11
Arthritis and Rheumatism, 50, 103-11

Contains fulltext : 57343.pdf (Publisher’s version ) (Closed access) OBJECTIVE: To investigate in vivo and in vitro whether macrophages have an intermediate role in transforming growth factor beta (TGFbeta)-induced osteophyte formation. METHODS: In

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e746c7de84c748d9716af5c7fe65700e
https://hdl.handle.net/2066/57343