Výsledky vyhledávání

Abstract P5-10-02: Development and validation of a polygenic score to predict breast cancer risk in unaffected Hispanic women negative for mutations on a multi-gene hereditary cancer panel

Autor: Susanne Wagner, K Bulka, Dmitry Pruss, T Perry, Srikanth Jammulapati, R Hoff, Elisha Hughes, Shannon Gallagher, Jerry S. Lanchbury, Alexander Gutin, Brad Swedlund, Brian Morris

Publikováno v: Cancer Research. 79:P5-10

Background: Breast cancer (BC) is the most commonly diagnosed cancer and the leading cause of cancer-related death among Hispanic women in the United States. For women of European ancestry, genome-wide association studies (GWAS) have identified commo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::89b8861ecddcec86d6871b2d4e5ad536
https://doi.org/10.1158/1538-7445.sabcs18-p5-10-02

Zobrazit plný text záznamu

Abstract P1-09-06: Prognostic and predictive relevance of cell cycle progression (CCP) score in ductal carcinoma in situ: Results from the UK/ANZ DCIS trial

Autor: Louise J. Jones, Nigel J Bundred, K Bulka, Darl D. Flake, Jack Cuzick, Susanne Wagner, Zaina Sangale, Jerry S. Lanchbury, Mangesh A. Thorat, R Hoff, John F. Forbes, PM Levey, Ian S. Fentiman

Publikováno v: Cancer Research. 77:P1-09

Background: The prognostic abilities of most gene expression signatures in breast cancer are often due to detection of proliferative activity measured from expression of genes regulated as a function of cell cycle progression. Cell Cycle Progression

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8a97ede0b93fb69d8a50e3620f8224b5
https://doi.org/10.1158/1538-7445.sabcs16-p1-09-06

Zobrazit plný text záznamu

Abstract P3-07-02: Prognostic and predictive relevance of HER2 status in ductal carcinoma in situ: Results from the UK/ANZ DCIS trial

Autor: Susanne Wagner, Louise J. Jones, Darl D. Flake, John F. Forbes, Jerry S. Lanchbury, Nigel J Bundred, Zaina Sangale, R Hoff, Mangesh A. Thorat, PM Levey, Ian S. Fentiman, K Bulka, Jack Cuzick

Publikováno v: Cancer Research. 76:P3-07

Background: As compared to invasive breast cancer (IBC), HER2 is much more frequently overexpressed in ductal carcinoma in situ (DCIS). Unlike IBC, the prognostic significance of HER2 overexpression remains to be established in DCIS and large studies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::877a33f51fe478df15ea11b3f1597afb
https://doi.org/10.1158/1538-7445.sabcs15-p3-07-02

Zobrazit plný text záznamu

Experience gained at the Novovoronezh nuclear power plant with development and introduction of a unified automated system for accounting and control of radioactive substances and radioactive wastes

Autor: S. K. Bulka, S. V. Rosnovskii

Publikováno v: Thermal Engineering. 61:144-152

A unified automated system for accounting and control of radioactive substances and radioactive wastes was developed at the Novovoronezh nuclear power plant. The system consists of several interconnected subsystems, which can be developed and put in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::799cabb6a559bc034189ce72523117a8
https://doi.org/10.1134/s0040601514020025

Zobrazit plný text záznamu

Prediction of the radiation situation during conditioned radioactive waste storage in hangar-type storage facilities

Autor: S. K. Bulka, S. V. Rosnovskii

Publikováno v: Thermal Engineering. 61:117-122

An original technology for the conditioning of solidified radioactive waste was developed by the Novovoronezh nuclear power plant (NPP) staff. The technology provides for waste placement inside NZK-150-1.5P containers with their further storage at li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9d3fc00ea583b16dfdb4b4a1d2dd3a96
https://doi.org/10.1134/s0040601514020116

Zobrazit plný text záznamu

Identification of a common variant in the lipoprotein lipase gene in a large Utah kindred ascertained for coronary heart disease: the −93G/D9N variant predisposes to low HDL-C/high triglycerides

Autor: K Bulka, Mark E. Samuels, Benjamin R. Bowen, Dennis G. Ballinger, Victor Abkevich, Julia Reid, BR Wardell, Steven C. Hunt, Paul N. Hopkins, Kristian C. Forbey, Mark H. Skolnick, Susanne Wagner

Publikováno v: Clinical Genetics. 59:88-98

Defects in the lipoprotein lipase (LPL) gene are associated with dyslipidemia in the general population. Several rare mutations in the gene, as well as two common coding region polymorphisms, D9N and N291S, exhibit deleterious effects on circulating

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::491bc0721bb850555a798fdda1f15246
https://doi.org/10.1034/j.1399-0004.2001.590205.x

Zobrazit plný text záznamu

Evidence of Linkage of Familial Hypoalphalipoproteinemia to a Novel Locus on Chromosome 11q23

Autor: Benjamin R. Bowen, Keith D Harshman, Wei Ding, C. Capener, K Bulka, Mark H. Skolnick, Victor Abkevich, Jathine Wong, Bryan Wardell, B. Campbell, E. N. Kort, Steven C. Hunt, M. McDermott, Hui-Chun Wang, Alexander Gutin, Dennis G. Ballinger, Mark E. Samuels, T. Thorne, Paul N. Hopkins

Publikováno v: The American Journal of Human Genetics. 66:1845-1856

Coronary heart disease (CHD) accounts for half of the 1 million deaths annually ascribed to cardiovascular disease and for almost all of the 1.5 million acute myocardial infarctions. Within families affected by early and apparently heritable CHD, dys

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b445f3f00551f89cb62ac16c66bc42
https://doi.org/10.1086/302945

Zobrazit plný text záznamu

Genetic Localization to Chromosome 1p32 of the Third Locus for Familial Hypercholesterolemia in a Utah Kindred

Autor: K Bulka, Dennis G. Ballinger, Mark E. Samuels, Benjamin R. Bowen, Mark H. Skolnick, Bryan Wardell, Thomas L. Thorne, Michael T. McDermott, Steven C. Hunt, Paul N. Hopkins

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 20:1089-1093

Abstract —Clinical familial hypercholesterolemia has been shown to result from mutations in 2 genes, the low density lipoprotein (LDL) receptor on chromosome 19 and apolipoprotein B on chromosome 2. However, we have recently described a Utah pedigr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32c7ee57308518dce340f2d157fa8976
https://doi.org/10.1161/01.atv.20.4.1089

Zobrazit plný text záznamu

Identification of a common variant in the lipoprotein lipase gene in a large Utah kindred ascertained for coronary heart disease: the -93G/D9N variant predisposes to low HDL-C/high triglycerides

Autor: M E, Samuels, K C, Forbey, J E, Reid, V, Abkevich, K, Bulka, B R, Wardell, B R, Bowen, P N, Hopkins, S C, Hunt, D G, Ballinger, M H, Skolnick, S, Wagner

Publikováno v: Clinical genetics. 59(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::43fc140977b0d964cfef228d15288890
https://pubmed.ncbi.nlm.nih.gov/11260209

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání