Zobrazeno 1 - 10
of 53
pro vyhledávání: '"K. Brogden"'
Publikováno v:
Operative Dentistry. 48:68-78
SUMMARY Objectives To evaluate chroma (C*) and overall color of double-layered (DL) resin composite (RC) restorations with various dentin shades and enamel thicknesses. Methods Enamel specimens were fabricated using custom-made molds to replicate VIT
Autor:
Celymar Ortiz-de León, Christopher J. Hartwick, Clara A. Stuedemann, Nicole K. Brogden, Leonard R. MacGillivray
Publikováno v:
Crystal Growth & Design. 22:6622-6626
A method to obtain single crystals of the opioid antagonist naloxone in the free base form is facilitated using mechanochemistry. The application of mechanochemistry reduces the number of steps and makes single crystals readily available from solutio
Publikováno v:
Pharmaceutical Research. 39:2515-2527
Treating chronic wounds is a significant clinical challenge, and a topical product would be ideal for pain management. Poloxamer 407, a thermosensitive polymer, would allow an analgesic drug to be topically applied to a wound as a liquid that transit
Publikováno v:
Pharmaceutics, Vol 12, Iss 12, p 1214 (2020)
Chronic wounds are a significant and growing health problem, and clinical treatment is often a painful experience. A topical dosage form would be optimal to treat this pain. Poloxamer 407, a thermosensitive polymer that is a liquid at low temperature
Externí odkaz:
https://doaj.org/article/b1ed789ec0b8495082cf8cb800f8e9d4
Publikováno v:
Pharmaceutics, Vol 12, Iss 6, p 496 (2020)
Naltrexone (NTX) hydrochloride is a potent opioid antagonist with significant first-pass metabolism and notable untoward effects when administered orally or intramuscularly. Microneedle (MN)-assisted transdermal delivery is an attractive alternative
Externí odkaz:
https://doaj.org/article/e6894fcacfd94174af485b065738175f
Autor:
Grant O. Holdren, David J. Rosenthal, Jianyi Yang, Amber M. Bates, Carol L. Fischer, Yang Zhang, Nicole K. Brogden, Kim A. Brogden
Publikováno v:
Antibiotics, Vol 3, Iss 4, Pp 527-539 (2014)
CXCL10 (IP-10) is a small 10 kDa chemokine with antimicrobial activity. It is induced by IFN-γ, chemoattracts mononuclear cells, and promotes adhesion of T cells. Recently, we detected CXCL10 on the surface of the skin and in the oral cavity. In the
Externí odkaz:
https://doaj.org/article/59bd5b95f08a43a582bcbc40373aef5d
Autor:
Nicole K. Brogden, Jamie Carr, Abayomi Tolulope Ogunjimi, Nkanyezi Ferguson, Christine K. Lawson, Krishna Kumar Patel
Publikováno v:
Skin Pharmacol Physiol
Introduction: The continuous availability of open micropores is crucial for a successful microneedle (MN) drug delivery strategy. However, micropore lifetime depends on intrinsic skin functional and anatomical characteristics, which vary significantl
Publikováno v:
Molecular Pharmaceutics. 19:4391-4391
Autor:
Nicole K. Brogden, Rebecca J. Benson, Kathryn Harmoney, Erin M. Mobley, Stephanie Gilbertson-White
Publikováno v:
J Palliat Med
Background: Growing evidence suggests that pediatric palliative care (PPC) teams influence the care received by children and young adults with chronic, life-limiting illnesses. Little is known about how PPC involvement affects advance care planning (
Autor:
Xinyi Gao, Nicole K. Brogden
Publikováno v:
J Pharm Sci
Transdermal naloxone delivery could be a potential option for treating opioid-induced pruritus, but naloxone does not permeate skin well because of its hydrophilic nature. Microneedles (MNs) could overcome the skin barrier by painlessly creating micr