Zobrazeno 1 - 10
of 34
pro vyhledávání: '"K. Breckwoldt"'
Autor:
Norbert Jost, Arne Hansen, K. Breckwoldt, Ingra Mannhardt, Hermann Reichenspurner, Christiane Neuber, Marc D Lemoine, Evaldas Girdauskas, Thomas Eschenhagen, Frederik Flenner, Alexandra Löser, Erich Wettwer, Torsten Christ, Stephan Willems, Ahmet Umur Uzun, András Horváth
Publikováno v:
Stem Cell Reports, Vol 10, Iss 3, Pp 822-833 (2018)
Stem Cell Reports
Stem Cell Reports
Summary Human induced pluripotent stem cell (hiPSC) cardiomyocytes (CMs) show less negative resting membrane potential (RMP), which is attributed to small inward rectifier currents (IK1). Here, IK1 was measured in hiPSC-CMs (proprietary and commercia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf1889c5e77734254d8a08de89ae5115
http://www.sciencedirect.com/science/article/pii/S2213671118300389
http://www.sciencedirect.com/science/article/pii/S2213671118300389
Autor:
David Letuffe-Brenière, K. Breckwoldt, Christiane Neuber, Ingra Mannhardt, Anika Benzin, Thomas Eschenhagen, Marc N. Hirt, Arne Hansen, Alexandra Eder, Birgit Klampe, Sebastian Schaaf, Herbert Schulz, Tessa Werner, Torsten Christ, Alessandra Moretti, Thomas G. Schulze, Norbert Huebner
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 7, Iss 1, Pp 29-42 (2016)
Stem Cell Reports, Vol 7, Iss 1, Pp 29-42 (2016)
Summary Analyzing contractile force, the most important and best understood function of cardiomyocytes in vivo is not established in human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM). This study describes the generation of 3D, str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a379265c2a2566e1d4a4ff629a62093
http://europepmc.org/articles/PMC4944531
http://europepmc.org/articles/PMC4944531
Autor:
K. Breckwoldt, Christian W. Remmele, Annette Just, Jan Fiedler, Angelika Pfanne, Marcus Dittrich, Thomas Eschenhagen, Dorothee Hartmann, Ke Xiao, Thomas Thum, Robert Geffers, Tobias Müller, Arne Hansen, Thomas Dandekar, Meik Kunz
Publikováno v:
Journal of the American College of Cardiology. 66:2005-2015
BackgroundLong noncoding ribonucleic acids (lncRNAs) are a subclass of regulatory noncoding ribonucleic acids for which expression and function in human endothelial cells and angiogenic processes is not well studied.ObjectivesThe authors discovered h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97d4f7294c254110939447af5dee1d6a
https://doi.org/10.1016/j.jacc.2015.07.081
https://doi.org/10.1016/j.jacc.2015.07.081
Autor:
Arne Hansen, Christiane Neuber, Marc D Lemoine, András Horváth, K. Breckwoldt, Bärbel M. Ulmer, Ingra Mannhardt, Thomas Eschenhagen, Frederik Flenner, Hermann Reichenspurner, Maksymilian Prondzynski, Torsten Christ, Stephan Willems, Benjamin Kloth, Marc N. Hirt
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
Scientific Reports
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) are a promising tool for drug testing and modelling genetic disorders. Abnormally low upstroke velocity is a current limitation. Here we investigated the use of 3D engineered heart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c546efc72ffbf9195f3c13d2d6bb7ffe
https://doi.org/10.1038/s41598-017-05600-w
https://doi.org/10.1038/s41598-017-05600-w
Autor:
Arne Hansen, K. Breckwoldt, Anika Benzin, Sandra D. Laufer, Elisabeth Krämer, Ingra Mannhardt, Marita L. Rodriguez, Christiane Neuber, Mirja L Schulze, Umber Saleem, David Letuffe-Brenière, Aya Shibamiya, Bärbel M. Ulmer, Giulia Mearini, Birgit Klampe, Maksymilian Prondzynski, Tessa Werner, Dennis Schade, Thomas G. Schulze, Sigrid Fuchs, Thomas Eschenhagen, Marina Reinsch
Publikováno v:
Nature protocols. 12(6)
Since the advent of the generation of human induced pluripotent stem cells (hiPSCs), numerous protocols have been developed to differentiate hiPSCs into cardiomyocytes and then subsequently assess their ability to recapitulate the properties of adult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14e6dfbddf03f6f12979d9f773d6cd75
https://pubmed.ncbi.nlm.nih.gov/31384055
https://pubmed.ncbi.nlm.nih.gov/31384055
Author Correction: Differentiation of cardiomyocytes and generation of human engineered heart tissue
Autor:
Arne Hansen, Sandra D. Laufer, Thomas Eschenhagen, Thomas G. Schulze, Christiane Neuber, Aya Shibamiya, K. Breckwoldt, Elisabeth Krämer, Ingra Mannhardt, Bärbel M. Ulmer, Sigrid Fuchs, Anika Benzin, David Brenière-Letuffe, Tessa Werner, Umber Saleem, Mirja L Schulze, Marita L. Rodriguez, Birgit Klampe, Dennis Schade, Maksymilian Prondzynski, Marina Reinsch, Giulia Mearini
Publikováno v:
Nature Protocols. 14:2748-2748
Please note that since the original publication of this paper, the author David Letuffe-Breniere has changed his name to David Breniere-Letuffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1ce5cd99114bb69e9eba6bd10dce2f3
https://doi.org/10.1038/s41596-019-0228-5
https://doi.org/10.1038/s41596-019-0228-5
Cardiac repair in guinea pigs with human engineered heart tissue from induced pluripotent stem cells
Autor:
Florian Weinberger, Katrin Lessmann, Arne Hansen, Kai-Hung Cheng, Jutta Starbatty, K. Breckwoldt, Simon Pecha, Tomas Stølen, Birgit Geertz, Godfrey L. Smith, Thomas Eschenhagen, Marielle Scherrer-Crosbie, Timur A. Yorgan, Allen Kelly, Hermann Reichenspurner
Publikováno v:
Science translational medicine. 8(363)
Myocardial injury results in a loss of contractile tissue mass that, in the absence of efficient regeneration, is essentially irreversible. Transplantation of human pluripotent stem cell–derived cardiomyocytes has beneficial but variable effects. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a21983ac43ffb9e7ab36d981707f77d
https://pubmed.ncbi.nlm.nih.gov/27807283
https://pubmed.ncbi.nlm.nih.gov/27807283
Autor:
H. Reichenspurner, Birgit Geertz, Arne Hansen, K. Breckwoldt, Simon Pecha, Thomas Eschenhagen, Florian Weinberger
Publikováno v:
The Thoracic and Cardiovascular Surgeon. 64
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0dfe385b4a9dd6e297bf2bd99a9315c
https://doi.org/10.1055/s-0036-1571691
https://doi.org/10.1055/s-0036-1571691
Autor:
Birgit Geertz, K. Breckwoldt, Jutta Starbatty, Arne Hansen, Simon Pecha, Florian Weinberger, Hermann Reichenspurner, Thomas Eschenhagen
Publikováno v:
The Thoracic and Cardiovascular Surgeon. 63
Objectives: Myocardial infarction causes unrecoverable loss of cardiomyocytes. Engineered heart tissue (EHT) is an in vitro model of three-dimensional cardiomyocyte network with morphological and functional similarity to native heart tissue. We trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7393a38d8870232ac4ef08b87f757d8
https://doi.org/10.1055/s-0035-1544361
https://doi.org/10.1055/s-0035-1544361