Zobrazeno 1 - 10
of 869
pro vyhledávání: '"K. Boyer"'
Publikováno v:
Royal Society Open Science, Vol 2, Iss 4 (2015)
For anthropologists, meat eating by primates like chimpanzees (Pan troglodytes) warrants examination given the emphasis on hunting in human evolutionary history. As referential models, apes provide insight into the evolution of hominin hunting, given
Externí odkaz:
https://doaj.org/article/7e792638246d486d877395c10cffe071
Autor:
Nancy Sue, Le May Thai, Atsushi Saito, Cierra K. Boyer, Ashleigh M. Fordham, Chenxu Yan, Aimee Davenport, Jiang Tao, Mohammed Bensellam, James Cantley, Yan-Chuan Shi, Samuel B. Stephens, Kazunori Imaizumi, Trevor J. Biden
Publikováno v:
Molecular Metabolism, Vol 79, Iss , Pp 101845- (2024)
Objective: Although individual steps have been characterized, there is little understanding of the overall process whereby glucose co-ordinates the biosynthesis of insulin with its export out of the endoplasmic reticulum (ER) and incorporation into i
Externí odkaz:
https://doaj.org/article/abf43cfa76f149028ed91ecd5b7f85a5
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract The pancreatic islet β-cell’s preference for release of newly synthesized insulin requires careful coordination of insulin exocytosis with sufficient insulin granule production to ensure that insulin stores exceed peripheral demands for g
Externí odkaz:
https://doaj.org/article/33b76294eda54b51bc2c9b04da020b7e
Autor:
Christie M. Penniman, Gourav Bhardwaj, Colette J. Nowers, Chandler U. Brown, Taylor L. Junck, Cierra K. Boyer, Jayashree Jena, Jordan D. Fuqua, Vitor A. Lira, Brian T. O'Neill
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 1, Pp 243-259 (2023)
Abstract Background Muscle mitochondrial decline is associated with aging‐related muscle weakness and insulin resistance. FoxO transcription factors are targets of insulin action and deletion of FoxOs improves mitochondrial function in diabetes. Ho
Externí odkaz:
https://doaj.org/article/c9f129a6962c4f9aa5ecf446caaba8e4
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 335 (2022)
Pancreatic islet β-cells exhibit tremendous plasticity for secretory adaptations that coordinate insulin production and release with nutritional demands. This essential feature of the β-cell can allow for compensatory changes that increase secretor
Externí odkaz:
https://doaj.org/article/a80f3bcbd8324d9cadb0474fb8129f28
Autor:
Christie M. Penniman, Gourav Bhardwaj, Colette J. Nowers, Chandler U. Brown, Taylor L. Junck, Cierra K. Boyer, Jayashree Jena, Jordan D. Fuqua, Vitor A. Lira, Brian T. O'Neill
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle. 14:243-259
Muscle mitochondrial decline is associated with aging-related muscle weakness and insulin resistance. FoxO transcription factors are targets of insulin action and deletion of FoxOs improves mitochondrial function in diabetes. However, disruptions in
Autor:
Y Zhou, K Leahy, A Grose, J Lykins, M Siddiqui, N. Leong, P Goodall, S Withers, K Ashi, S Schrantz, V Tesic, A P Abeleda, K Beavis, F Clouser, M Ismail, M Christmas, R Piarroux, D Limonne, E Chapey, S Abraham, I Baird, J Thibodeau, K Boyer, E Torres, S Conrey, K Wang, MA Staat, N Back, J Gomez Marin, F Peyron, S Houze, M Wallon, R McLeod
Publikováno v:
medRxiv
BackgroundCongenital toxoplasmosis is a treatable, preventable disease, but untreated causes death, prematurity, loss of sight, cognition and motor function, and substantial costs worldwide.Methods/FindingsIn our ongoing USA feasibility/efficacy clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::176792bafbc1573849fed6ee42d849b2
https://europepmc.org/articles/PMC10168490/
https://europepmc.org/articles/PMC10168490/
Autor:
Shadrack J. Barnabas, Timo Böhme, Stephen K. Boyer, Matthias Irmer, Christoph Ruttkies, Ian Wetherbee, Todor Kondić, Emma L. Schymanski, Lutz Weber
Publikováno v:
Digital Discovery. 1:490-501
Extracting PFAS with open source cheminformatics toolkits reveals ~1.78 million PFAS in Google Patents, ~28 K in the CORE literature repository. The extraction of chemical information from documents is a demanding task in cheminformatics due to the v
Autor:
PE Campos, O Pruvost, K Boyer, F Chiroleu, TT Cao, M Gaudeul, C Baider, TMA Utteridge, S Dominick, N Becker, A Rieux, L Gagnevin
Over the past decade, the field of ancient genomics has triggered considerable progress in the study of various pathogens, including those affecting crops. In this context, herbarium collections have been an important source of dated, identified and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f4bed8f9881d0b36f24d199c29cc989
https://doi.org/10.1101/2022.12.08.519547
https://doi.org/10.1101/2022.12.08.519547
Autor:
Kristen E Rohli, Cierra K Boyer, Shelby C Bearrows, Marshall R Moyer, Weston S Elison, Casey J Bauchle, Sandra E Blom, Jianchao Zhang, Yanzhuang Wang, Samuel B Stephens
Publikováno v:
Function (Oxford, England). 3(6)
Defects in the pancreatic β-cell’s secretion system are well-described in type 2 diabetes (T2D) and include impaired proinsulin processing and a deficit in mature insulin-containing secretory granules; however, the cellular mechanisms underlying t