Zobrazeno 1 - 10
of 451
pro vyhledávání: '"K. Berthold"'
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 913 (2024)
Lipid-lowering therapy (LLT) is a cornerstone of atherosclerotic cardiovascular disease prevention. Although LLT might lead to different reductions in low-density lipoprotein cholesterol (LDL-C) levels in women and men, LLT diminishes cardiovascular
Externí odkaz:
https://doaj.org/article/6f48164bd7a84a4c8948801d33ffca72
Autor:
Armin Zittermann, Jana B. Ernst, Sylvana Prokop, Uwe Fuchs, Heiner K. Berthold, Ioanna Gouni‐Berthold, Jan F. Gummert, Stefan Pilz
Publikováno v:
ESC Heart Failure, Vol 7, Iss 6, Pp 3754-3761 (2020)
Abstract Aims Vitamin D supplementation is widely used in the clinical setting, but its effects on mortality and cardiovascular outcomes in patients with heart failure are unclear. This paper reports outcome data that were collected during follow‐u
Externí odkaz:
https://doaj.org/article/1f079bb5be1e4730b0ae06d5da13593e
Autor:
Eberhard Windler, Frank-Ulrich Beil, Heiner K. Berthold, Ioanna Gouni-Berthold, Ursula Kassner, Gerald Klose, Stefan Lorkowski, Winfried März, Klaus G. Parhofer, Jogchum Plat, Günter Silbernagel, Elisabeth Steinhagen-Thiessen, Oliver Weingärtner, Birgit-Christiane Zyriax, Dieter Lütjohann
Publikováno v:
Nutrients, Vol 15, Iss 4, p 828 (2023)
Phytosterols (PSs) have been proposed as dietary means to lower plasma LDL-C. However, concerns are raised that PSs may exert atherogenic effects, which would offset this benefit. Phytosterolemia was thought to mimic increased plasma PSs observed aft
Externí odkaz:
https://doaj.org/article/c6af7126e5e7432d9deb69568ac283b4
Autor:
Armin Zittermann, Jana B. Ernst, Sylvana Prokop, Uwe Fuchs, Jens Dreier, Joachim Kuhn, Cornelius Knabbe, Jochen Börgermann, Heiner K. Berthold, Stefan Pilz, Ioanna Gouni-Berthold, Jan F. Gummert
Publikováno v:
International Journal of Endocrinology, Vol 2018 (2018)
Objective. 1,25-Dihydroxyvitamin D (1,25([OH]2D) is considered to be a negative endogenous regulator of the renin-angiotensin-aldosterone system (RAAS), but the effect of vitamin D supplementation on the RAAS is inconclusive. Design. In this prespeci
Externí odkaz:
https://doaj.org/article/f75d4f77b48a4dd7be83d3a01d200ae6
Autor:
Nike Müller, Dominik M. Schulte, Kathrin Türk, Sandra Freitag-Wolf, Jochen Hampe, Rainald Zeuner, Johann O. Schröder, Ioanna Gouni-Berthold, Heiner K. Berthold, Wilhelm Krone, Stefan Rose-John, Stefan Schreiber, Matthias Laudes
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 5, Pp 1034-1042 (2015)
Lipoprotein (a) [Lp(a)] is a highly atherogenic lipid particle. Although earlier reports suggested that Lp(a) levels are mostly determined by genetic factors, several recent studies have revealed that Lp(a) induction is also caused by chronic inflamm
Externí odkaz:
https://doaj.org/article/1e84b394b05a42729d49afcf37b71719
Publikováno v:
Nutrients, Vol 6, Iss 12, Pp 5517-5533 (2014)
The serine protease proprotein convertase subtilisin/kexin type 9 (PCSK9) binds to the low-density lipoprotein (LDL) receptor (LDLR) and directs it to lysosomes for intracellular degradation. This results in decreased numbers of LDLR available on the
Externí odkaz:
https://doaj.org/article/7589ef672b7f4250a282d49af43d4a6a
Akademický článek
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Autor:
Christopher C. Warren, Ryan J. Monello, Seth W. Judge, Hanna L. Mounce, Patrick J. Hart, Laura K. Berthold, Richard J. Camp
Publikováno v:
Journal of Field Ornithology. 92:115-126
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ed8495a0f57d9bd33bc34c0bd8a8340
https://doi.org/10.1111/jofo.12364
https://doi.org/10.1111/jofo.12364
Publikováno v:
Current atherosclerosis reports. 24(10)
Purpose of Review To report on recent data about PCSK9 monoclonal antibodies and to evaluate their relevance in a nucleic acid–based therapy era for lipid lowering and prevention of cardiovascular disease. Recent Findings New methods of PCSK9 inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bab753f1275c1eebc7fbd07c54347b0
https://pubmed.ncbi.nlm.nih.gov/35900635
https://pubmed.ncbi.nlm.nih.gov/35900635
Autor:
Ilaria Campesi, Mark L. Heiman, Heiner K. Berthold, Vera Regitz-Zagrosek, Anne Z. Murphy, Santosh Dakal, Ioanna Gouni-Berthold, Franck Mauvais-Jarvis, Karen Reue, Flavia Franconi, Juan Jesus Carrero, Joshua B. Rubin, Sabra L. Klein, Alexandra Kautzky-Willer
Publikováno v:
Pharmacological Reviews. 73:730-762
In humans, the combination of all sex-specific genetic, epigenetic, and hormonal influences of biologic sex produces different in vivo environments for male and female cells. We dissect how these influences of sex modify the pharmacokinetics and phar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0070083e86b30ec88536a82bcbe8aee6
https://doi.org/10.1124/pharmrev.120.000206
https://doi.org/10.1124/pharmrev.120.000206