Zobrazeno 1 - 10
of 38
pro vyhledávání: '"K. Beardshall"'
Publikováno v:
Regulatory Peptides. 40:1-12
We have developed and validated a new radioimmunoassay for cholecystokinin. In order to establish that the antiserum binds large and small forms of CCK to an equal extent, we used the microbial enzyme clostripain, which cleaves large forms of CCK yie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::609df16dd837b142cfe0a45067394c30
https://doi.org/10.1016/0167-0115(92)90079-a
https://doi.org/10.1016/0167-0115(92)90079-a
Autor:
S Levi, Steven F. Moss, John Calam, Raymond J. Playford, P. Ghosh, K. Beardshall, Janusz Gill
Publikováno v:
Gut. 33:601-603
Helicobacter pylori increases gastrin release in duodenal ulcer patients. This may be through disruption or changes in the mucus layer affecting the access of luminal stimulants to gastrin releasing cells. The effect of suppressing H pylori on gastri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe8f9ffd1cc540bf823d677fcc75d82
https://doi.org/10.1136/gut.33.5.601
https://doi.org/10.1136/gut.33.5.601
Publikováno v:
Neuropeptides. 25(4)
We have investigated the possibility of measuring acid secretion from human gastric mucosa in vitro as a potential pharmacological preparation. We used open-ended 10 microns-tip, lix-based glass microelectrodes to measure the pH of the mucus layer of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f52f612fafc5d8d19863d522cb8c0d35
https://pubmed.ncbi.nlm.nih.gov/8255402
https://pubmed.ncbi.nlm.nih.gov/8255402
Autor:
David A. Vesey, G C Fenn, J J Batten, Tom C. Freeman, Raymond J. Playford, K. Beardshall, John Calam, J H Baron
Publikováno v:
Playford, R J, Batten, J J, Freeman, T C, Beardshall, K, Vesey, D A, Fenn, G C, Baron, J H & Calam, J 1991, ' Gastric output of pancreatic secretory trypsin inhibitor is increased by misoprostol ', Gut, vol. 32, no. 11, pp. 1396-400 .
Pancreatic secretory trypsin inhibitor (PSTI) is a potent protease inhibitor that also has growth promoting activity. It has recently been identified in the foveolar cells of the stomach, which secrete mucus. We examined the effects of the prostaglan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14be3244444a98e114d488c8bf803dfb
https://www.pure.ed.ac.uk/ws/files/9358392/Gastric_output_of_pancreatic_secretory_trypsin_inhibitor_is_increased_by_misoprostol.pdf
https://www.pure.ed.ac.uk/ws/files/9358392/Gastric_output_of_pancreatic_secretory_trypsin_inhibitor_is_increased_by_misoprostol.pdf
Gastrin is trophic to colon cancers that possess gastrin receptors. Whether fasting serum gastrin concentrations are high in patients with colon cancer is controversial. We therefore studied the effect of food on serum gastrin concentrations in patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccbf21abc62ea4324e305808777ba6b0
https://europepmc.org/articles/PMC1379166/
https://europepmc.org/articles/PMC1379166/
Autor:
C. E. Sarraf, Malcolm R. Alison, John Calam, K. Beardshall, R. C. N. Williamson, E. F. Efa, P. Watanapa
Since pancreatobiliary diversion probably stimulates pancreatic growth by increasing cholecystokinin secretion, the effect of the cholecystokinin antagonist CR-1409 on this adaptive response was tested. Male Wistar rats (n = 108) weighing 220-250g we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8e875e00b2ff1e968e760c0759c7ed0
https://europepmc.org/articles/PMC1379049/
https://europepmc.org/articles/PMC1379049/
Publikováno v:
The British journal of surgery. 78(8)
Proximal small bowel resection causes pancreatic hyperplasia, presumably via a humoral mechanism. Although cholecystokinin can stimulate pancreatic growth, its proximal distribution in the gut makes it an unlikely intermediary after proximal small bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55a07357765e316e2558bbff75c966a0
https://pubmed.ncbi.nlm.nih.gov/1717100
https://pubmed.ncbi.nlm.nih.gov/1717100
Autor:
John Calam, Raymond J. Playford, Tom C. Freeman, L Poulter, J Young, K. Beardshall, Cecily Quinn
Publikováno v:
Freeman, T C, Playford, R J, Quinn, C, Beardshall, K, Poulter, L, Young, J & Calam, J 1990, ' Pancreatic secretory trypsin inhibitor in gastrointestinal mucosa and gastric juice ', Gut, vol. 31, no. 11, pp. 1318-23 .
We studied the distribution of pancreatic secretory trypsin inhibitor (PSTI) in the epithelia of the gastrointestinal tract and determined whether PSTI is secreted into gastric juice. PSTI was measured by a specific radioimmunoassay in biopsy specime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5a0c5e244cb23524cb532a557f8532f
https://pubmed.ncbi.nlm.nih.gov/2253919
https://pubmed.ncbi.nlm.nih.gov/2253919
Autor:
I Swift, Raymond J. Playford, G. Haddad, William D. Foulkes, K. Beardshall, P. Ghosh, John Calam, S. Levi
Publikováno v:
Helicobacter pylori, Gastritis and Peptic Ulcer ISBN: 9783642753176
Our work represents an attempt to understand the relationship between the “traditional” view that increased acid secretion is an important cause of duodenal ulcers (DUs) and the new evidence that DU is caused by Helicobacter pylori (HP).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95e6480c710c3703e16903b8c45073e7
https://doi.org/10.1007/978-3-642-75315-2_46
https://doi.org/10.1007/978-3-642-75315-2_46
Publikováno v:
Regulatory Peptides. 35:223
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a519356116ab506de9e86549434ce9e
https://doi.org/10.1016/0167-0115(91)90086-v
https://doi.org/10.1016/0167-0115(91)90086-v