Zobrazeno 1 - 10
of 465
pro vyhledávání: '"K. Barry Sharpless"'
Autor:
Hyunseok Kim, Jiayu Zhao, Jinhye Bae, Liana M. Klivansky, Eric A. Dailing, Yi Liu, John R. Cappiello, K. Barry Sharpless, Peng Wu
Publikováno v:
ACS Central Science, Vol 7, Iss 11, Pp 1919-1928 (2021)
Externí odkaz:
https://doaj.org/article/2ce1051c622e41c890fcff70c7afb740
Autor:
Leopold Garnar-Wortzel, Timothy R. Bishop, Seiya Kitamura, Natalia Milosevich, Joshua N. Asiaban, Xiaoyu Zhang, Qinheng Zheng, Emily Chen, Anissa R. Ramos, Christopher J. Ackerman, Eric N. Hampton, Arnab K. Chatterjee, Travis S. Young, Mitchell V. Hull, K. Barry Sharpless, Benjamin F. Cravatt, Dennis W. Wolan, Michael A. Erb
Publikováno v:
ACS Central Science, Vol 7, Iss 5, Pp 815-830 (2021)
Externí odkaz:
https://doaj.org/article/097fa2b7ad3f4a1fa4c7766ad3a5dcd3
Autor:
Senlian Hong, Yujie Shi, Nicholas C. Wu, Geramie Grande, Lacey Douthit, Hua Wang, Wen Zhou, K. Barry Sharpless, Ian A. Wilson, Jia Xie, Peng Wu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Glycan molecules can be modified directly on the cell surface via chemoenzymatic approaches. Here, the authors employ a set of four bacterial glycosyltransferases to develop a live cell-based killing assay to probe host cell glycan-mediated influenza
Externí odkaz:
https://doaj.org/article/95fae0db46a849ee85349e633d348698
Autor:
He Li, Boyce S. Chang, Hyunseok Kim, Zongliang Xie, Antoine Lainé, Le Ma, Tianlei Xu, Chongqing Yang, Junpyo Kwon, Steve W. Shelton, Liana M. Klivansky, Virginia Altoé, Bing Gao, Adam M. Schwartzberg, Zongren Peng, Robert O. Ritchie, Ting Xu, Miquel Salmeron, Ricardo Ruiz, K. Barry Sharpless, Peng Wu, Yi Liu
Publikováno v:
Joule. 7:95-111
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::783ea1bc53523b57efeaccfd31cb06ad
https://doi.org/10.1016/j.joule.2022.12.010
https://doi.org/10.1016/j.joule.2022.12.010
Autor:
Tineke Lauwaet, Yukiko Miyamoto, Sozaburo Ihara, Christine Le, Jarosław Kalisiak, Keith A Korthals, Majid Ghassemian, Diane K Smith, K Barry Sharpless, Valery V Fokin, Lars Eckmann
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 4, p e0008224 (2020)
Giardiasis and other protozoan infections are major worldwide causes of morbidity and mortality, yet development of new antimicrobial agents with improved efficacy and ability to override increasingly common drug resistance remains a major challenge.
Externí odkaz:
https://doaj.org/article/ed36932d78294388be2840c2e73d1b52
Autor:
Ye Xin, Shuo Liu, Yan Liu, Zhen Qian, Hongyue Liu, Bingjie Zhang, Taijie Guo, Garth J. Thompson, Raymond C. Stevens, K. Barry Sharpless, Jiajia Dong, Wenqing Shui
Publikováno v:
Proceedings of the National Academy of Sciences. 120
The recently developed double-click reaction sequence [G. Meng et al. , Nature 574 , 86–89 (2019)] is expected to vastly expand the number and diversity of synthetically accessible 1,2,3-triazole derivatives. However, it remains elusive how to rapi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cc3d9f3cb03d64d951c4a389b4227a5
https://doi.org/10.1073/pnas.2220767120
https://doi.org/10.1073/pnas.2220767120
Autor:
Yunfei Cheng, Gencheng Li, Christopher J. Smedley, Marie-Claire Giel, Seiya Kitamura, Jordan L. Woehl, Giulia Bianco, Stefano Forli, Joshua A. Homer, John R. Cappiello, Dennis W. Wolan, John E. Moses, K. Barry Sharpless
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(37)
Diversity Oriented Clicking (DOC) is a discovery method geared toward the rapid synthesis of functional libraries. It combines the best attributes of both classical and modern click chemistries. DOC strategies center upon the chemical diversification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ddd6832eae3169fcf0154bb5c5df3d1
https://pubmed.ncbi.nlm.nih.gov/36070343
https://pubmed.ncbi.nlm.nih.gov/36070343
Autor:
K. Barry Sharpless, Yi Liu, Eric A. Dailing, John R. Cappiello, Liana M. Klivansky, Hyunseok Kim, Jinhye Bae, Peng Wu, Jiayu Zhao
Publikováno v:
ACS Central Science, Vol 7, Iss 11, Pp 1919-1928 (2021)
ACS Central Science
ACS central science, vol 7, iss 11
ACS Central Science
ACS central science, vol 7, iss 11
Sulfur(VI) fluoride exchange (SuFEx) click chemistry has offered a facile and reliable approach to produce polysulfates and polysulfonates. However, the current SuFEx polymerization methods lack precise control of target molecular weight and dispersi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a8bf6768198c38111d1689292906d9
https://doaj.org/article/2ce1051c622e41c890fcff70c7afb740
https://doaj.org/article/2ce1051c622e41c890fcff70c7afb740
Autor:
Shoujun Sun, Christopher J. Smedley, Joshua A. Homer, Qing-Qing Cheng, K. Barry Sharpless, John E. Moses
We report catalytic Phosphorus Fluoride Exchange (PFEx) as the latest advance in connective click-reaction technology. Emulating Nature, PFEx reaches into the biological world and creates stable tetrahedral P(V)- connections through efficient phospho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::095aef47e4657f6a93573fffec54f6e5
https://doi.org/10.26434/chemrxiv-2022-nc91f
https://doi.org/10.26434/chemrxiv-2022-nc91f
Autor:
Nathan M. Samskey, Palmer Taylor, Zoran Radić, Arnold Garcia, Yadira Sepulveda, Rakesh K. Sit, K. Barry Sharpless, Jeremiah D. Momper, Yan Jye Shyong
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 378:315-321
Inhibition of acetylcholinesterase (AChE) by certain organophosphates (OPs) can be life-threatening and requires reactivating antidote accessibility to the peripheral and central nervous systems to reverse symptoms and enhance survival parameters. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d91471633449ad7f8cc9ca68c86ba077
https://doi.org/10.1124/jpet.121.000715
https://doi.org/10.1124/jpet.121.000715