Zobrazeno 1 - 10
of 55
pro vyhledávání: '"K. B. Elkon"'
Publikováno v:
The Journal of Immunology. 159:4628-4636
Mutations in the Fas receptor or its ligand (FasL) lead to lupus-like systemic autoimmune diseases in mice and in some humans. To determine whether a significant number of patients with systemic lupus erythematosus (SLE) have impaired FasL function,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27d82eda540b4c2e8adafccc92ad6296
https://doi.org/10.4049/jimmunol.159.9.4628
https://doi.org/10.4049/jimmunol.159.9.4628
Publikováno v:
The Journal of Immunology. 159:2058-2067
MRL/MpJ-Fas(lpr) (Fas(lpr)) mice develop a rapidly fatal form of systemic autoimmune disease characterized by glomerulonephritis and vasculitis similar to severe cases of systemic lupus erythematosus in humans. To evaluate the requirement for interce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::324527a3931868dfc55951365398663e
https://doi.org/10.4049/jimmunol.159.4.2058
https://doi.org/10.4049/jimmunol.159.4.2058
Publikováno v:
The Journal of Immunology. 157:5387-5393
Recent studies have suggested a role for the Fas pathway in the wasting syndrome associated with lpr-->wild-type bone marrow transplants. To directly examine whether Fas ligand has a major role in the development of acute graft-vs-host disease (GVHD)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34e1f8533cc23b0e0e970f63ce487388
https://doi.org/10.4049/jimmunol.157.12.5387
https://doi.org/10.4049/jimmunol.157.12.5387
Publikováno v:
Journal of Clinical Investigation. 90:1105-1109
A subset of patients with systemic lupus erythematosus has autoantibodies to acidic phospholipids. Since lipids are poor immunogens, the mechanism responsible for the induction of these antibodies is unclear. Immunization of a normal rabbit and norma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1445d73160d1d9c6b506287f2b8847a
https://doi.org/10.1172/jci115927
https://doi.org/10.1172/jci115927
Publikováno v:
The Journal of Immunology. 149:1409-1415
Although proteinase 3 (PR3) has been identified as a major autoantigen in Wegener's granulomatosis, the precise antibody specificity(ies) and requirements for epitope recognition have not been characterized. We analyzed 11 sera containing antineutrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a7b161ae588471105b609d371cf1ca3
https://doi.org/10.4049/jimmunol.149.4.1409
https://doi.org/10.4049/jimmunol.149.4.1409
Publikováno v:
The Journal of Immunology. 145:636-643
SmB and SmB' are the major antigenic proteins contained within small nuclear RNP particles that are recognized by both human SLE and MRL mouse anti-Sm sera. We amplified cDNA obtained from HeLa cells by using the polymerase chain reaction and identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6c21fed3382cd936f5dcb7a0402ff7c
https://doi.org/10.4049/jimmunol.145.2.636
https://doi.org/10.4049/jimmunol.145.2.636
Publikováno v:
Clinical and experimental immunology. 127(2)
SummaryThe Canale–Smith syndrome (CSS) is an inherited disease characterized by massive lymphadenopathy, hepatosplenomegaly and systemic autoimmunity to erythrocytes and platelets. Idiopathic thrombocytopenic purpura (ITP) is an autoimmune disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cf2b6cf762a8c6ce5b4edb56e629ccf
https://pubmed.ncbi.nlm.nih.gov/11876752
https://pubmed.ncbi.nlm.nih.gov/11876752
Publikováno v:
Reviews in immunogenetics. 2(2)
Homeostasis within the immune system is complicated by the need to selectively force the survival of potentially useful lymphocytes in the central lymphoid organs and of antigen-reactive cells in the periphery. Coupled with this requirement, is the n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::56b39ced9edc8b0289b5357eee2e1907
https://pubmed.ncbi.nlm.nih.gov/11258424
https://pubmed.ncbi.nlm.nih.gov/11258424
Autor:
K. B. Elkon
Publikováno v:
Hughes Syndrome ISBN: 9781852332327
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b326c8c76da8b8b15a7eedb5acbf929
https://doi.org/10.1007/978-1-4471-3666-8_37
https://doi.org/10.1007/978-1-4471-3666-8_37
Autor:
A K, Vaishnaw, E, Toubi, S, Ohsako, J, Drappa, S, Buys, J, Estrada, A, Sitarz, L, Zemel, J L, Chu, K B, Elkon
Publikováno v:
Arthritis and rheumatism. 42(9)
To determine the clinical spectrum of disease in humans with mutations in the CD95 (Fas/ APO-1) receptor and to obtain mechanistic insight into the different clinical phenotypes observed.Clinical information for each of the index cases, first-degree
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d507aa5a8b9755c10c91ead3411a17c4
https://pubmed.ncbi.nlm.nih.gov/10513797
https://pubmed.ncbi.nlm.nih.gov/10513797