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pro vyhledávání: '"K. Ashley Hickman"'
Autor:
Santosh Hariharan, Jason De Melo, Lindsay C. Lustig, Linda Z. Penn, K Ashley Hickman, Jarkko Ylanko, David W. Andrews
Publikováno v:
Cytometry
Short half-life proteins regulate many essential processes, including cell cycle, transcription, and apoptosis. However, few well-characterized protein-turnover pathways have been identified because traditional methods to measure protein half-life ar
Autor:
Sara Helander, Maria Sunnerhagen, K. Ashley Hickman, Brian Raught, Robert Pilstål, Igor Jurisica, Corey Lourenco, Linda Z. Penn, Björn Wallner, William B. Tu
Publikováno v:
Biochimica et biophysica acta. 1849(5)
The Myc oncoprotein is a key contributor to the development of many human cancers. As such, understanding its molecular activities and biological functions has been a field of active research since its discovery more than three decades ago. Genome-wi
Autor:
Christina Bros, Warren W.C Chan, Linda Z. Penn, K. Ashley Hickman, Romina Ponzielli, Jumi Shin, Lindsay C. Lustig, Dharmendra Dingar
Publikováno v:
Molecular Cancer Research. 13:A24-A24
When deregulated, the c-Myc oncoprotein plays a key role in the development and progression of over 50% of all human cancers. As such, innovative and effective therapeutics are urgently needed to improve the treatment and survival of cancer patients,