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Autor: KristaJoy K. Altland, David E. Avery, Hans G. Dam

Publikováno v: Limnology and Oceanography. 53:2627-2635

In this study we hypothesized that the sexes of the copepod Acartia hudsonica experience different mortalities when exposed to the toxic dinoflagellate Alexandrium fundyense. In laboratory experiments, we manipulated toxin dose and measured sex-speci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::feb237c3a6a90b101d5c5319c83cd3cd
https://doi.org/10.4319/lo.2008.53.6.2627

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D18G Transthyretin Is Monomeric, Aggregation Prone, and Not Detectable in Plasma and Cerebrospinal Fluid: A Prescription for Central Nervous System Amyloidosis?

Autor: Yoshiki Sekijima, A. Lim, F. Garzuly, Jeffery W. Kelly, R.L. Wiseman, Per Hammarström, Catherine E. Costello, H. Budka, K. Altland, Joleen T. White

Publikováno v: Biochemistry. 42:6656-6663

Over 70 transthyretin (TTR) mutations facilitate amyloidosis in tissues other than the central nervous system (CNS). In contrast, the D18G TTR mutation in individuals of Hungarian descent leads to CNS amyloidosis. D18G forms inclusion bodies in Esche

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6c6aa4af0f4df8de094affb01ab090c
https://doi.org/10.1021/bi027319b

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A distinct gene close to the hairless locus on chromosome 8p underlies hereditary Marie Unna type hypotrichosis in a German family

Autor: Martina Anker, Roland Kruse, Guido M. Kukuk, Sven Cichon, Axel M. Hillmer, K. Altland, Markus M. Nöthen, Peter Propping, Michael Knapp

Publikováno v: British Journal of Dermatology. 143:811-814

BACKGROUND: Hypotrichosis of the Marie Unna type (HMU) is a rare autosomal dominant disorder characterized by male-pattern hair loss with childhood onset and anomalies of the hair shaft. OBJECTIVES: We aimed to evaluate a number of chromosomal loci a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d50ffbe33b5306a8a6b50bc058e60997
https://doi.org/10.1046/j.1365-2133.2000.03781.x

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Structural analysis of human apolipoprotein A-I variants. Amino acid substitutions are nonrandomly distributed throughout the apolipoprotein A-I primary structure

Autor: Gerd Assmann, Michael Walter, Harald Funke, K Altland, A Benninghoven, A. von Eckardstein

Publikováno v: Journal of Biological Chemistry. 265:8610-8617

In the course of an electrophoretic mutation screening program of 32,000 dried blood samples from newborns, 17 genetic variants of apolipoprotein A-I (apoA-I) were found and structurally analyzed. The following defects were identified by the combined

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::87cba86638a9bf10d1b6456bd4ae0343
https://doi.org/10.1016/s0021-9258(19)38931-8

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'Sporadic' familial amyloidotic polyneuropathy in a German patient with B cell lymphocytic leukaemia

Autor: Mathias Buttmann, Martin Marziniak, Klaus V. Toyka, Claudia Sommer, K Altland

We report a 70 year old German man presenting with a three year history of progressive numbness and painful tingling and burning paraesthesiae in his hands, feet, and lower legs, which had worsened during recent months. He also reported unsteadiness

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c440924e15510b1e44f72874379c33e
https://europepmc.org/articles/PMC1757318/

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The in-vitro influence of serum amyloid A isoforms on enzymes that regulate the balance between esterified and un-esterified cholesterol

Autor: M. K. Stehen-Muller, R. Bauer, R. Klett, Reinhold P. Linke, K. Altland, M. Puille, D. Steiner

Publikováno v: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis. 8(3)

The intracellular balance between un-esterified and esterified cholesterol is regulated by two enzyme activities, cholesterol ester hydrolases, which drive the balance in favor of un-esterified cholesterol, and acyl-CoA:cholesterol acyl transferase (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b9e20075bd5cc82859121c6b1424f7
https://pubmed.ncbi.nlm.nih.gov/11676294

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