Zobrazeno 1 - 10
of 21
pro vyhledávání: '"K. A. Narahara"'
Autor:
J N, Cohn, M B, Fowler, M R, Bristow, W S, Colucci, E M, Gilbert, V, Kinhal, S K, Krueger, T, Lejemtel, K A, Narahara, M, Packer, S T, Young, T L, Holcslaw, M A, Lukas
Publikováno v:
Journal of cardiac failure. 3(3)
Many patients remain markedly symptomatic despite optimal current therapy for heart failure. Beta-blockers have often been viewed as contraindicated in this group because of their potential adverse short-term effects on cardiac function.One hundred t
Autor:
M R, Bristow, E M, Gilbert, W T, Abraham, K F, Adams, M B, Fowler, R E, Hershberger, S H, Kubo, K A, Narahara, H, Ingersoll, S, Krueger, S, Young, N, Shusterman
Publikováno v:
Circulation. 94(11)
We conducted a multicenter, placebo-controlled trial designed to establish the efficacy and safety of carvedilol, a "third-generation" beta -blocking agent with vasodilator properties, in chronic heart failure.Three hundred forty-five subjects with m
Autor:
K A, Narahara
Publikováno v:
The American journal of medicine. 95(5)
The spontaneous variation of the left and right ventricular ejection fractions (LVEF and RVEF) was evaluated in patients with chronic heart failure receiving only digoxin and diuretics over a 12-week interval.Fifty-one patients with stable heart fail
Publikováno v:
Journal of the American College of Cardiology. 22(1)
The aim of this study was to assess the efficacy of flosequinan in chronic heart failure.Flosequinan is a new vasodilator drug that acts by interfering with the inositol-triphosphate/protein kinase C pathway, an important mechanism of vasoconstrictio
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 34(2)
It is thought that the distribution of 99mTc-sestamibi undergoes minimal change during the first 4 hr after injection. Thus [99mTc] sestamibi unlike 201Tl should not demonstrate significant redistribution in ischemic myocardium. We tested this assump
Autor:
K A, Narahara
Publikováno v:
American heart journal. 121(5)
In a parallel study design, 164 patients with New York Heart Association Functional class II or III heart failure were randomized to receive either enoximone given as 50 mg three times a day, or 100 mg three times a day, or a matching placebo. All pa
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 31(4)
The newly developed technetium-99m (99mTc) isonitriles can be used for the simultaneous evaluation of ventricular function and myocardial perfusion. We compared technetium-99m hexakis-2-methoxy isobutyl isonitrile [( 99mTc] MIBI) derived first-pass l
Autor:
K A, Narahara
Publikováno v:
The American journal of cardiology. 65(9)
Betaxolol is a new, highly cardioselective, once-a-day beta blocker with a long half-life (mean 16 hours). The antianginal efficacy of 2 doses of betaxolol (20 and 40 mg) given once daily was evaluated and compared with propranolol (40 or 80 mg) 4 ti
Autor:
K. A. Narahara, J. V. Nixon, K. M. Lipscomb, L. L. Burden, T. C. Smitherman, M. C. Hillert, W. Shapiro
Publikováno v:
Clinical Cardiology. 3:309-316
The pathophysiologic basis for the deterioration of patients with stable angina pectoris to unstable angina is unclear. Central to this issue is the question of whether myocardial ischemia occurs at the same or at a lower myocardial oxygen demand dur
Publikováno v:
Circulation. 62:1248-1255
To determine whether real-time two-dimensional echocardiography (2-D echo) can estimate the extent of myocardial involvement in patients with acute myocardial infarction (MI), regional wall motion on serial short-axis 2-D echo recordings was analyzed