Výsledky vyhledávání - "K. A. Lillycrop"

Differential DNA methylation of steatosis and non-alcoholic fatty liver disease in adolescence

Autor: Phillip E. Melton, M. A. Burton, K. A. Lillycrop, K. M. Godfrey, S. Rauschert, D. Anderson, G. C. Burdge, T. A. Mori, L. J. Beilin, O. T. Ayonrinde, J. M. Craig, J. K. Olynyk, J. D. Holbrook, C. E. Pennell, W. H. Oddy, E. K. Moses, L. A. Adams, R. C. Huang

Background and aims Epigenetic modifications are associated with hepatic fat accumulation and non-alcoholic fatty liver disease (NAFLD). However, few epigenetic modifications directly implicated in such processes have been identified during adolescen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f79d7abb8c6cbd2fbfa59b4bd58260af
https://eprints.soton.ac.uk/474099/

Zobrazit plný text záznamu

Alternative splicing of the Oct-2 transcription factor RNA is differentially regulated in neuronal cells and B cells and results in protein isoforms with opposite effects on the activity of octamer/TAATGARAT-containing promoters

Autor: D S Latchman, K A Lillycrop

Publikováno v: Journal of Biological Chemistry. 267:24960-24965

The RNA encoding the octamer-binding transcription factor Oct-2 is alternatively spliced in both neuronal cells and in B cells to yield multiple mRNAs encoding different isoforms of the protein. We show that, compared with B cells, neuronal cells ove

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f06dfad1f480822ff39c04dc6c8e967
https://doi.org/10.1016/s0021-9258(19)73991-x

Zobrazit plný text záznamu

The B-cell and neuronal forms of the octamer-binding protein Oct-2 differ in DNA-binding specificity and functional activity

Autor: C L Dent, K A Lillycrop, J K Estridge, N S Thomas, D S Latchman

Publikováno v: Molecular and Cellular Biology. 11:3925-3930

B lymphocytes contain an octamer-binding transcription factor, Oct-2, that is absent in most other cell types and plays a critical role in the B-cell-specific transcription of the immunoglobulin genes. A neuronal form of this protein has also been de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ff054f9ceb66da2cd5e1909c5fdbcc1b
https://doi.org/10.1128/mcb.11.8.3925

Zobrazit plný text záznamu

Effect of fatty acid supplementation on growth and differentiation of human IMR-32 neuroblastoma cells in vitro

Autor: G C, Burdge, H, Rodway, J A, Kohler, K A, Lillycrop

Publikováno v: Journal of cellular biochemistry. 80(2)

Polyunsaturated fatty acids play a critical role in the structure and function of the developing nervous system. It has been proposed that fatty acids may effect a variety of biologic processes through the activation of the peroxisome proliferator ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::30dd54fa05baa19846552b0194acea02
https://pubmed.ncbi.nlm.nih.gov/11074598

Zobrazit plný text záznamu

Autor: K A, Lillycrop, D S, Latchman

Publikováno v: The Journal of biological chemistry. 267(35)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1e58c56bcdfa651786f4434cc7bc22df
https://pubmed.ncbi.nlm.nih.gov/1281152

Zobrazit plný text záznamu

Regulation of expression of the neuronal POU protein Oct-2 by nerve growth factor

Autor: J N, Wood, K A, Lillycrop, C L, Dent, N N, Ninkina, M M, Beech, J J, Willoughby, J, Winter, D S, Latchman

Publikováno v: The Journal of biological chemistry. 267(25)

POU proteins are a class of homeobox-containing transcription factors that regulate tissue-specific gene expression and influence cell differentiation and function. We have investigated the possible role of such factors in mediating the actions of ne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8594eb5e9f63a77c8b6ab8ce1ebf6af9
https://pubmed.ncbi.nlm.nih.gov/1381354

Zobrazit plný text záznamu

Interferon-alpha treatment of Daudi cells down-regulates the octamer binding transcription/DNA replication factors Oct-1 and Oct-2

Autor: C L, Dent, K A, Lillycrop, A, Bybee, D S, Latchman, N S, Thomas

Publikováno v: The Journal of biological chemistry. 266(31)

Treatment of Daudi cells with alpha-interferon (alpha-IFN) results in a considerable decrease in the levels of the octamer-binding DNA replication/transcription factors Oct-1 and Oct-2 and specifically inhibits gene expression by octamer-containing p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4b039e9123c412e4281786b9d048b27b
https://pubmed.ncbi.nlm.nih.gov/1939139

Zobrazit plný text záznamu

Genome-wide methylation analysis identifies differentially methylated CpG loci associated with severe obesity in childhood

Autor: R C Huang, E S Garratt, H Pan, Y Wu, E A Davis, S J Barton, G C Burdge, K M Godfrey, J D Holbrook, K A Lillycrop

Childhood obesity is a major public health issue. Here we investigated whether differential DNA methylation was associated with childhood obesity. We studied DNA methylation profiles in whole blood from 78 obese children (mean BMI Z-score: 2.6) and 7

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f475c6b14f0f6f5914a4e050144c9114

Zobrazit plný text záznamu

Genome-wide methylation analysis identifies differentially methylated CpG loci associated with severe obesity in childhood

Autor: R C Huang, E S Garratt, H Pan, Y Wu, E A Davis, S J Barton, G C Burdge, K M Godfrey, J D Holbrook, K A Lillycrop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0e26211b5e7c51c423011e512a3e4b6e

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání