Výsledky vyhledávání - "K. A. Engleka"

Endothelial cell DNA transfer and expression using Petri dish electroporation and the nonreplicating vaccinia virus/T7 RNA polymerase hybrid system

Autor: E W Lewis, A W Heinze, T J Rudo, MA Rahman St John, Bruce H. Howard, J L Chu, K A Engleka

Publikováno v: Gene Therapy. 6:1617-1625

The nonreplicating vaccinia virus MVA/T7 RNA polymerase hybrid system was tested with Petri dish electroporation for ectopic gene expression in human umbilical vein endothelial cells (HUVECs). A range of voltages (150-450 V), pulse times (10-40 ms),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9962feed10b5f85d5effa46efabb1930
https://doi.org/10.1038/sj.gt.3300977

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Differential transforming abilities of non-secreted and secreted forms of human fibroblast growth factor-1

Autor: R. Forough, Z Xi, K A Engleka, T Sayers, Martin Macphee, Thomas Maciag, Stanley Friedman, R H Wiltrout

Publikováno v: Journal of Biological Chemistry. 268:2960-2968

Fibroblast growth factor (FGF)-1(1-154), the precursor for acidic FGF-1(21-154), is a potent angiogenic polypeptide, the structure of which lacks a signal peptide sequence for secretion. To investigate the biological significance of this structural f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::97758e07e38e45d379a6b88a1f5aa587
https://doi.org/10.1016/s0021-9258(18)53867-9

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Inactivation of human fibroblast growth factor-1 (FGF-1) activity by interaction with copper ions involves FGF-1 dimer formation induced by copper-catalyzed oxidation

Autor: Thomas Maciag, K A Engleka

Publikováno v: Journal of Biological Chemistry. 267:11307-11315

Although the angiogenic proteins acidic fibroblast growth factor (FGF-1) and basic fibroblast growth factor (FGF-2) both interact with the transition metal copper, itself a putative modulator of angiogenesis, a role for copper in FGF function has not

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6429afe147d728c625251ce4d8ebcb92
https://doi.org/10.1016/s0021-9258(19)49911-0

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Detection of high levels of heparin binding growth factor-1 (acidic fibroblast growth factor) in inflammatory arthritic joints

Autor: Jeanette A.M. Maier, T. Maciag, John Case, Ronald L. Wilder, K. A. Engleka, Hajime Sano, R. Forough, A. O. Jackson

Publikováno v: The Journal of Cell Biology
Scopus-Elsevier

The synovium from patients with rheumatoid arthritis (RA) and LEW/N rats with streptococcal cell wall (SCW) arthritis, an experimental model resembling RA, is characterized by massive proliferation of synovial connective tissues and invasive destruct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c640d2564f25b9f348752f05d9a2c4af
http://europepmc.org/articles/PMC2116104

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Inactivation of human fibroblast growth factor-1 (FGF-1) activity by interaction with copper ions involves FGF-1 dimer formation induced by copper-catalyzed oxidation

Autor: K A, Engleka, T, Maciag

Publikováno v: The Journal of biological chemistry. 267(16)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3b7458e4ca9573f43259457e2cf87e8b
https://pubmed.ncbi.nlm.nih.gov/1375939

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