Zobrazeno 1 - 10
of 27
pro vyhledávání: '"K. A. Boomars"'
Autor:
T. Koudstaal, D. van Uden, J. A. C. van Hulst, P. Heukels, I. M. Bergen, L. W. Geenen, V. J. M. Baggen, A. E. van den Bosch, L. M. van den Toorn, P. P. Chandoesing, M. Kool, E. Boersma, R. W. Hendriks, K. A. Boomars
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-13 (2021)
Abstract Background Recent studies have provided evidence for an important contribution of the immune system in the pathophysiology of pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). In this report, we
Externí odkaz:
https://doaj.org/article/5f628a5ac8dd448486f8bea92b62db59
Autor:
Peter Heukels, Mirjam Kool, Rudi W. Hendriks, Leon M. van den Toorn, Marlies S. Wijsenbeek, K. A. Boomars, Jennifer A C van Hulst, Odilia B. J. Corneth, Annemien E. van den Bosch, Denise van Uden
Publikováno v:
Thorax, 76(12), 1209-1218. BMJ Publishing Group
Thorax
Thorax
IntroductionAutoreactivity against pulmonary vascular structures is thought to be involved in idiopathic pulmonary arterial hypertension (IPAH), but the underlying mechanisms remain poorly understood. We hypothesised that aberrant B-cell activation c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2c2f4418e6b11fb4f5d512ce6b8f8f6
https://pure.eur.nl/en/publications/4c4cdc2f-8a87-4ba3-a6af-29db99265b02
https://pure.eur.nl/en/publications/4c4cdc2f-8a87-4ba3-a6af-29db99265b02
Autor:
Paulien Vinke, Michiel G.J. Balvers, Thomas Koudstaal, Mieke Poland, Klaske van Norren, K. A. Boomars, Annemien E. van den Bosch, Renger F. Witkamp, Femke Muskens
Publikováno v:
Nutrients
Volume 13
Issue 11
Nutrients, 13(11):3923. Multidisciplinary Digital Publishing Institute (MDPI)
Nutrients, Vol 13, Iss 3923, p 3923 (2021)
Nutrients, 13(11)
Nutrients 13 (2021) 11
Volume 13
Issue 11
Nutrients, 13(11):3923. Multidisciplinary Digital Publishing Institute (MDPI)
Nutrients, Vol 13, Iss 3923, p 3923 (2021)
Nutrients, 13(11)
Nutrients 13 (2021) 11
Background: Pulmonary hypertension (PH) is a rare progressive and lethal disease affecting pulmonary arteries and heart function. The disease may compromise the nutritional status of the patient, which impairs their physical performance. This study a
Autor:
Monique Wapenaar, M C J Van Thor, M.C. Post, K. A. Boomars, Paul M. Hendriks, L M van den Toorn, A E Van Den Bosch, Prewesh Chandoesing
Publikováno v:
European Heart Journal. 42
Background Health-related quality of life (HRQoL) is impaired in patients with pulmonary hypertension (PH). The EmPHasis-10 and CAMPHOR questionnaires are developed to evaluate HRQoL specifically in patients with PH. Data on the longitudinal use of b
Autor:
Annemien E. van den Bosch, Mitch C.J. van Thor, Marco C. Post, Monique Wapenaar, Leon M. van den Toorn, Prewesh Chandoesing, K. A. Boomars, Paul M. Hendriks
Publikováno v:
Respiratory Medicine, 186:106525. W.B. Saunders
Background Health-related quality of life (HRQoL) is impaired in patients with pulmonary hypertension (PH). The EmPHasis-10 and CAMPHOR questionnaires are developed to evaluate HRQoL specifically in patients with PH. Data on the longitudinal use of b
Autor:
Peter Heukels, K. A. Boomars, Prewesh Chandoesing, Mirjam Kool, L M van den Toorn, A E Van Den Bosch, Eric Boersma, J. A. C. van Hulst, Vivan J.M. Baggen, Rudolf W. Hendriks, Thomas Koudstaal, Laurie W Geenen, D. van Uden, Ingrid M. Bergen
Publikováno v:
Respiratory Research, 22(1):137. BioMed Central Ltd.
Respiratory Research, Vol 22, Iss 1, Pp 1-13 (2021)
Respiratory Research
Respiratory Research, Vol 22, Iss 1, Pp 1-13 (2021)
Respiratory Research
Background Recent studies have provided evidence for an important contribution of the immune system in the pathophysiology of pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). In this report, we investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b878201a2dd62beea9fed2f6beee4dc
https://pure.eur.nl/en/publications/6d58687c-c102-4f7a-aae7-0fa331369788
https://pure.eur.nl/en/publications/6d58687c-c102-4f7a-aae7-0fa331369788
Autor:
Jolien W. Roos-Hesselink, Thomas Koudstaal, K. A. Boomars, Robert M Kauling, Eric Boersma, Annemien E. van den Bosch, Laurie W Geenen, Vivan J.M. Baggen
Publikováno v:
Heart, 106, 467-473. BMJ Publishing Group
ObjectiveDespite its predictive value for mortality in various diseases, the relevance of growth differentiation factor-15 (GDF-15) as prognostic biomarker in pulmonary hypertension (PH) remains unclear. This study investigated the association betwee
Autor:
K. A. Boomars, Frédéric Perros, Maria-Rosa Ghigna, Chelsea Gootjes, Rudi W. Hendriks, David Montani, Geert van Loo, Denise van Uden, Thomas Koudstaal, Mirjam Kool, Thierry P P van den Bosch, Nicholas W. Morrell, Jan H. von der Thüsen, Jennifer A C van Hulst, Ingrid M. Bergen
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 1756, p 1756 (2021)
International Journal of Molecular Sciences, 22(4):1756, 1-19. Multidisciplinary Digital Publishing Institute (MDPI)
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 22
Issue 4
International Journal of Molecular Sciences, Vol 22, Iss 1756, p 1756 (2021)
International Journal of Molecular Sciences, 22(4):1756, 1-19. Multidisciplinary Digital Publishing Institute (MDPI)
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 22
Issue 4
The pathogenesis of idiopathic pulmonary arterial hypertension (IPAH) is not fully understood, but evidence is accumulating that immune dysfunction plays a significant role. We previously reported that 31-week-old Tnfaip3DNGR1-KO mice develop pulmona
Autor:
T. Koudstaal, D. Van Uden, J. A. C. Van Hulst, P. Heukels, I. M. Bergen, L. W. Geenen, V. J. M. Baggen, A. E. Van Den Bosch, L. M. Van Den Toorn, P. P. Chandoesing, M. Kool, E. Boersma, R. W. Hendriks, K. A. Boomars
Additional file 1: Figure 1. Effects of CXCL9 and IL-8 plasma levels on patient survival. Figure 2. Plasma concentrations of IL-1β and IL-6 Inflammatory markers in plasma of PAH and CTEPH patients at diagnosis and 1-year follow up. Figure 3. Inflamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::475c4a4b0555f160de36886d2acb5aa8
Autor:
M. van Faassen, Laurie W Geenen, Irwin K.M. Reiss, Ly Tu, A E Van Den Bosch, Zongye Cai, Ido P. Kema, Dirk J. Duncker, Daphne Merkus, Siyu Tian, K. A. Boomars, C van der Ley, Christophe Guignabert, J.B De Rijke, Theo Klein
Publikováno v:
European Heart Journal, 41, 3814-3814. Oxford University Press
Background De novo NAD+ synthesis through the tryptophan-kynurenine (TK) metabolism was recognized as an important pathway in improving mitochondrial function and survival of injury or apoptotic cells, which are key processes involved in the pathogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7084d0c84faac5dab31bd9d29ad4e82
https://research.rug.nl/en/publications/f6d3840b-5bf0-4459-99b0-58eec381c14b
https://research.rug.nl/en/publications/f6d3840b-5bf0-4459-99b0-58eec381c14b