Zobrazeno 1 - 10
of 16
pro vyhledávání: '"K. A. Dugi"'
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 9, Pp 1822-1832 (1997)
In order to evaluate the coordinate role that hepatic lipase (HL) and lecithin:cholesterol acyltransferase (LCAT) play in modulating HDL particle heterogeneity and function in vivo we utilized recombinant adenovirus to express HL in control and LCAT
Externí odkaz:
https://doaj.org/article/056c9c361c5c4141b003f30aefc40f69
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 3, Pp 651-661 (1996)
Familial lipoprotein lipase (LPL) deficiency is an inherited disorder of lipoprotein metabolism characterized by hypertriglyceridemia and recurrent episodes of abdominal pain and pancreatitis. We have studied the genetic basis of LPL deficiency in a
Externí odkaz:
https://doaj.org/article/f3b3c559415b4b72ad34c68b0b2b62d5
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 6, Pp 1213-1223 (1996)
We have identified the underlying molecular defect in a patient with hepatic lipase (HL) deficiency presenting with hypertriglyceridemia and premature cardiovascular disease. DNA sequencing of polymerase chain reaction (PCR) amplified DNA and digesti
Externí odkaz:
https://doaj.org/article/93f7be2605b94c4b8fee833f0c074dbb
Autor:
P S, Wild, T, Zeller, M, Beutel, M, Blettner, K A, Dugi, K J, Lackner, N, Pfeiffer, T, Münzel, S, Blankenberg
Publikováno v:
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz. 55(6-7)
The Gutenberg Health Study is a population-based, prospective, single-center cohort study that started in 2007 at the University Medical Center Mainz. The project focuses on cardiovascular diseases, cancer, eye diseases, metabolic diseases, diseases
Publikováno v:
Diabetic medicine : a journal of the British Diabetic Association. 28(11)
To examine the efficacy and safety of the dipeptidyl peptidase-4 inhibitor linagliptin in persons with Type 2 diabetes mellitus inadequately controlled [HbA(1c) 53-86 mmol/mol (7.0-10.0%)] by metformin and sulphonylurea combination treatment.A multi-
Autor:
T, Forst, B, Uhlig-Laske, A, Ring, U, Graefe-Mody, C, Friedrich, K, Herbach, H-J, Woerle, K A, Dugi
Publikováno v:
Diabetic medicine : a journal of the British Diabetic Association. 27(12)
The efficacy and safety of the dipeptidyl peptidase-4 inhibitor, linagliptin, added to ongoing metformin therapy, were assessed in patients with Type 2 diabetes who had inadequate glycaemic control (HbA(1c) ≥ 7.5 to ≤ 10%; ≥ 58.5 to ≤ 85.8 mm
Autor:
M J, Amar, K A, Dugi, C C, Haudenschild, R D, Shamburek, B, Foger, M, Chase, A, Bensadoun, R F, Hoyt, H B, Brewer, S, Santamarina-Fojo
Publikováno v:
Journal of lipid research. 39(12)
We have investigated the role of hepatic lipase (HL) in remnant lipoprotein metabolism independent of lipolysis by using recombinant adenovirus to express native and catalytically inactive HL (HL-145G) in apolipoprotein (apo)E-deficient mice characte
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 17(7)
Abstract We have studied the underlying molecular defect in a patient presenting with recurrent pancreatitis, hypertriglyceridemia, and virtually undetectable postheparin plasma lipoprotein lipase (LPL) mass and activity, who normalized her triglycer
Autor:
J, Kobayashi, D, Applebaum-Bowden, K A, Dugi, D R, Brown, V S, Kashyap, C, Parrott, C, Duarte, N, Maeda, S, Santamarina-Fojo
Publikováno v:
The Journal of biological chemistry. 271(42)
Hepatic lipase (HL) and lipoprotein lipase (LPL) are key enzymes involved in the hydrolysis of triglycerides and phospholipids present in circulating plasma lipoproteins. Despite their similarities, the role that each of these two lipases play in the
Publikováno v:
Journal of lipid research. 37(6)
We have identified the underlying molecular defect in a patient with hepatic lipase (HL) deficiency presenting with hypertriglyceridemia and premature cardiovascular disease. DNA sequencing of polymerase chain reaction (PCR) amplified DNA and digesti