Zobrazeno 1 - 10
of 333
pro vyhledávání: '"K.‐F. Sewing"'
Publikováno v:
DMW - Deutsche Medizinische Wochenschrift. 113:311-314
Publikováno v:
Carcinogenesis. 21:1111-1115
Helicobacter pylori infection has been considered as a risk factor for gastric carcinoma. Strong evidence exists that reactive oxygen species (ROS) play an important role in carcinogenesis, and in vivo investigations have shown increased synthesis of
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids. 59:49-54
The glycosylation of pig gastric mucins, discharged in response to prostaglandin (PG) E 2 and to three synthetic PGE-derivatives (misoprostol, nocloprost, rioprostil) was compared. After a 20 h culture period in the absence or presence of 1 μmol/l o
Publikováno v:
British Journal of Cancer
Protein kinase C (PKC) has been implicated in the control of epithelial proliferative activity and in the process of malignant transformation. Helicobacter pylori (H.p.) infection is associated with increased gastric epithelial cell proliferation and
Publikováno v:
Biochemical Pharmacology. 54:761-772
Adult hepatocytes from rat and man were maintained for 2 weeks between two gel layers in a sandwich configuration to study the influence of this culture technique on the preservation of basal activities of xenobiotic-metabolizing phase I and phase II
Autor:
Hans-Martin Schiebel, B D Kahan, K F Sewing, F Streit, Uwe Christians, A Linck, L Ernst, K L Napoli
Publikováno v:
Scopus-Elsevier
Sirolimus (rapamycin) has a macrolide structure and is under clinical investigation as an immunosuppressant after organ transplantation. An HPLC/mass spectrometry assay to quantify sirolimus in blood was developed. 28-O-Acetyl sirolimus was used as i
Publikováno v:
European Journal of Clinical Investigation. 26:797-802
Phosphatidylcholine (PC) is the major phospholipid of the hydrophobic gastric mucosal barrier and is chiefly released from mucous cells into the gastric mucus. Whereas the mucosa contains highly unsaturated PC, gastric mucus predominantly contains pa
Publikováno v:
Clinical Chemistry. 42:1426-1432
The metabolite patterns of tacrolimus in blood were evaluated in 41 kidney and liver graft recipients. Trough concentrations of tacrolimus and its metabolites were measured by HPLC-mass spectrometry and microparticle enzyme immunoassay in parallel. A
Autor:
U. Frei, Jörg S. Bleck, H. Repp, K F Sewing, Michael Manns, C. Thiesemann, Hartmut Hecker, Uwe Christians, V. Kliem, Mechthild Westhoff-Bleck
Publikováno v:
British Journal of Clinical Pharmacology. 41:551-556
1Six male and six female stable renal allograft recipients under cyclosporine immunosuppression and without concomitant therapy with drugs known either to induce or inhibit CYP3A enzymes were included in the study and received 180 mg day−1 diltiaze
Publikováno v:
Digestive Diseases and Sciences. 40:678-684
The role of somatostatin-14 in duodenal mucosal HCO3- secretion was investigated in anesthetized, indomethacin-treated guinea pigs. Net HCO3- output from the isolated, perfused (24 mM NaHCO3 + 130 mM NaCl) proximal duodenum was measured during intrav