Zobrazeno 1 - 10
of 102
pro vyhledávání: '"K., Krishna Sharma"'
Autor:
K. Krishna Sharma, Rajashekhar Zulpe
Publikováno v:
Journal of Drug Delivery and Therapeutics. 13:X1-X4
Background: Varicose Veins are a valve incomitance disorder of the veins. Most persons who suffer from Varicose Veins very often do not get substantially relieved by the current medical treatment. A holistic approach to yoga has the potential to prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9989eba8c954e03fea7ad0209538f563
https://doi.org/10.22270/jddt.v13i1.5911
https://doi.org/10.22270/jddt.v13i1.5911
Autor:
Srinivas Mutalik, Tenzin Tender, Raghu Chandrashekar Hariharapura, Anuraag Muralidharan, K. Krishna Sharma, Pallavi K. Shetty
Publikováno v:
Current Drug Delivery. 18:1330-1337
Background: Inflammation has become the culmination point for several chronic diseases like skin diseases, asthma, neurological disorders, cancer, and cardiovascular disorders. Mini αA-crystallin peptide, identified from a highly conserved region of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b6cb17a304f2e7041604b850fdd9380
https://doi.org/10.2174/1567201818666210303095120
https://doi.org/10.2174/1567201818666210303095120
Publikováno v:
Biochemistry
The G98R mutation in αA-crystallin is associated with the onset of pre-senile cataract and is characterized biochemically by an increased oligomeric mass, altered chaperone function, and loss of structural stability over time. Thus far, it is not kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed4d8b14b5cbd9267c3b5c3bb14dc230
https://doi.org/10.1021/acs.biochem.9b00374
https://doi.org/10.1021/acs.biochem.9b00374
Autor:
K. Krishna Sharma, Peter F. Kador, Ashutosh S. Phadte, Marjorie F. Lou, Puttur Santhoshkumar, Damian M. Daszynski, Haizhen A. Zhong
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports
Scientific Reports
The paradigm that cataracts are irreversible and that vision from cataracts can only be restored through surgery has recently been challenged by reports that oxysterols such as lanosterol and 25-hydroxycholesterol can restore vision by binding to αB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f48cba3f41f04ae1fafb52d4b945629
http://link.springer.com/article/10.1038/s41598-019-44676-4
http://link.springer.com/article/10.1038/s41598-019-44676-4
Autor:
Sridevi Balireddy, Madhavan Nampoothiri, Hariharapura Raghu Chandrashekar, Rakesh Ravishankar Rahangdale, Tenzin Tender, K. Krishna Sharma
Publikováno v:
Medical Oncology (Northwood, London, England)
Abstract Chemotherapy-induced peripheral neuropathy (CIPN) is the most prevalent neurological complication of cancer treatment which involves sensory and motor nerve dysfunction. Severe CIPN has been reported in around 5% of patients treated with sin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18493c97bb3a5d32ef587ee94992ce5f
https://doi.org/10.1007/s12032-021-01496-9
https://doi.org/10.1007/s12032-021-01496-9
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65610 (2013)
Cataract is characterized by progressive protein aggregation and loss of vision. α-Crystallins are the major proteins in the lens responsible for maintaining transparency. They exist in the lens as highly polydisperse oligomers with variable numbers
Externí odkaz:
https://doaj.org/article/d2d668099d0140d8a7dae8283047cebd
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44077 (2012)
A substitution mutation in human αA-crystallin (αAG98R) is associated with autosomal dominant cataract. The recombinant mutant αAG98R protein exhibits altered structure, substrate-dependent chaperone activity, impaired oligomer stability and aggre
Externí odkaz:
https://doaj.org/article/6bf238bc46ec4602bc167495e5d5d10b
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19291 (2011)
The eye lens is composed of fiber cells that are filled with α-, β- and γ-crystallins. The primary function of crystallins is to maintain the clarity of the lens through ordered interactions as well as through the chaperone-like function of α-cry
Externí odkaz:
https://doaj.org/article/d49a9ed3fed243f59df069aff4435310
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10771, p 10771 (2021)
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10771, p 10771 (2021)
Previously, we showed that the removal of the 54–61 residues from αB-crystallin (αBΔ54–61) results in a fifty percent reduction in the oligomeric mass and a ten-fold increase in chaperone-like activity. In this study, we investigated the oligo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71ac9b426083a70ac4863663e18e4c66
https://doi.org/10.3390/ijms221910771
https://doi.org/10.3390/ijms221910771
Autor:
Rashida Patel, Shavinthi W Wadanamby, Hannah S. Thomas, Thomas Shortland, Binay Gurung, J Edward Fitzgerald, Melika Akhbari, Isobel Trout, K. Krishna Sharma, Adrian D Smith, Soham Bandyopadhyay
Background Global health is the study, research, and practice of medicine focused on improving health and achieving health equity for all persons worldwide. Such focuses are core tenets of modern medical practice. The General Medical Council (GMC) ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64d2e30de2cad122d436b95abcd00c1a
https://ora.ox.ac.uk/objects/uuid:7ccc3296-231b-4331-a19e-39dc2091a468
https://ora.ox.ac.uk/objects/uuid:7ccc3296-231b-4331-a19e-39dc2091a468
