Výsledky vyhledávání - "K., Hamakova"

C-reactive protein, chemerin, fetuin-A and osteopontin as predictors of cardiovascular risks in persons with psoriasis vulgaris

Autor: P, Borsky, Z, Fiala, C, Andrys, M, Beranek, K, Hamakova, J, Kremlacek, A, Malkova, T, Svadlakova, J, Krejsek, V, Palicka, V, Rehacek, L, Kotingova, L, Borska

Publikováno v: Physiol Res

The study aimed to contribute to understanding the role of CRP, chemerin, fetuin-A and osteopontin and to assess their suitability as biomarkers of early stages of cardiovascular diseases in psoriasis vulgaris. Serum levels measured in 28 patients an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::62ec705c2960f68b74afd0ae5b20a6de
https://pubmed.ncbi.nlm.nih.gov/33982577

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Variation of selected genotoxic and epigenetic markers due to therapeutic exposure to PAHs and ultraviolet radiation

Autor: Pavel Borsky, Ctirad Andrys, Martin Beranek, Zdeněk Fiala, Jan Kremlacek, Lenka Borska, Marcela Chmelarova, K. Hamakova, Vladimir Palicka, Andrea Malkova

Publikováno v: Bratislavske lekarske listy. 121(8)

BACKGROUND Goeckerman therapy (GT) of psoriasis involves dermal application of crude coal tar containing polycyclic aromatic hydrocarbons (PAHs) and exposure to ultraviolet radiation (UVR). Little is known about GT influence on DNA epigenetics. OBJEC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60fc221449ad6d36fc6861879cf573b8
https://pubmed.ncbi.nlm.nih.gov/32726118

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Roles of miR-31 and Endothelin-1 in Psoriasis Vulgaris: Pathophysiological Functions and Potential Biomarkers

Autor: Martin Beranek, Jan Krejsek, K. Hamakova, H Kovarikova, Vladimir Palicka, Jan Kremlacek, Lenka Borska, Zdeněk Fiala, Pavel Borsky, Marcela Chmelarova, Ctirad Andrys

Publikováno v: Scopus-Elsevier
Europe PubMed Central

Psoriatic lesions are characterized by hyperproliferation, aberrant differentiation of keratinocytes resistant to apoptosis and inflammation. miR-31 plays pro-proliferative, pro-differentiative and pro-inflammatory roles and modulates apoptosis in ps

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d4ca80770169306b48e37f3f8843d4a
https://doi.org/10.33549/physiolres.933615

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Serum Level of Antibodies (IgG, IgM) Against Benzo[a]pyrene-7,8-diol-9,10-epoxide-DNA Adducts in Children Dermatologically Exposed to Coal Tar

Autor: Pavel Borský, Ctirad Andrýs, Andrea Malkova, Zdeněk Fiala, K. Hamakova, Vladimir Palicka, Lenka Borska, Jan Krejsek, Lenka Bartošová, Jan Kremlacek

Publikováno v: Acta Medica, Vol 60, Iss 1, Pp 27-31 (2017)

Crude coal tar (CCT) contains polycyclic aromatic hydrocarbons (PAHs). Benzo[a]pyrene (BaP) is metabolized into a highly reactive metabolite benzo[a]pyrene-7,8-diol-9,10-epoxide (BPDE) that is able to bind to DNA and creates BPDE-DNA adducts. Adducte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28b5f1e27f3abfe3ee594f930d6e903f
https://doi.org/10.14712/18059694.2017.46

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Droplet Digital PCR Analysis of GSTM1 Deletion Polymorphism in Psoriatic Subjects Treated with Goeckerman Therapy

Autor: K. Hamakova, Vladimir Palicka, Zdeněk Fiala, Lenka Borska, Ctirad Andrýs, Martin Beranek, Jan Kremlacek

Publikováno v: Acta Medica, Vol 59, Iss 3, Pp 75-78 (2016)

Goeckerman therapy (GT) represents an effective treatment of psoriasis including a combination of pharmaceutical grade crude coal tar (CCT) and ultraviolet irradiation (UV-R). Coal tar contains a mixture of polycyclic aromatic hydrocarbons. The best

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa8de105a59feceabb123359a20697fc
https://actamedica.lfhk.cuni.cz/59/3/0075/

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Elevated levels of circulating biomarkers of cell death (nucleosomes) in the patients with plaque psoriasis treated with the Goeckerman regimen

Autor: Pavel Borsky, Lenka Borska, Zdenek Fiala, D. Ranna, K. Hamakova, Jan Krejsek, Jan Kremlacek, Ctirad Andrys

Publikováno v: Europe PubMed Central

BACKGROUND Nucleosomes are complexes that are formed during apoptosis. Psoriasis is a chronic skin disease characterized by keratinocyte hyperproliferation and anti-apoptotic features. Presented study was focused to expression of circulating biomarke

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c7f84109784f0797649fe93f1e7d8bd
https://doi.org/10.4149/bll_2014_047

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Akademický článek

Variation of selected genotoxic and epigenetic markers due to therapeutic exposure to PAHs and ultraviolet radiation.

Autor: P., Borsky, M., Chmelarova, Z., Fiala, V., Palicka, M., Beranek, J., Kremlacek, C., Andrys, K., Hamakova, A., Malkova, L., Borska

Publikováno v: Bratislava Medical Journal / Bratislavské Lekárske Listy; 2020, Vol. 121 Issue 8, p558-564, 7p

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