Zobrazeno 1 - 10
of 600
pro vyhledávání: '"K von der Mark"'
Autor:
Yan Jing, B de Crombrugghe, Jun Wang, K von der Mark, Jian Q. Feng, Junjun Jing, Xin Zhou, Robert J. Hinton, Xianglong Han
Publikováno v:
Journal of Dental Research. 94:1668-1675
For decades, it has been widely accepted that hypertrophic chondrocytes undergo apoptosis prior to endochondral bone formation. However, very recent studies in long bone suggest that chondrocytes can directly transform into bone cells. Our initial in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9fe7ccde09f55035c392188d1b77f07
https://doi.org/10.1177/0022034515598135
https://doi.org/10.1177/0022034515598135
Publikováno v:
Zeitschrift für Orthopädie und ihre Grenzgebiete. 137:386-392
PURPOSE Autogenous chondrocyte transplantation (ACT) is a promising but disputable new method for the treatment of full thickness hyaline cartilage defects. Neither long-term follow-up studies nor prospective randomised comparative clinical trials ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79103324f319c8cc5306825c6f5597ec
https://doi.org/10.1055/s-2008-1037378
https://doi.org/10.1055/s-2008-1037378
Publikováno v:
Current Gene Therapy. 3:305-317
Damage of articular cartilage is a frequent clinical problem and is commonly considered to be irreversible. Full-thickness defects may lead to the formation of fibrous repair tissue of minor mechanical quality, while partial-thickness lesions hardly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f88cfd03f4db049011f4f1efba63f89e
https://doi.org/10.2174/1566523034578276
https://doi.org/10.2174/1566523034578276
Autor:
Jung Park, Jutta Ries, Jörg Wiltfang, Friedrich Wilhelm Neukam, Holm Schneider, Kolja Gelse, K von der Mark, F. R. Kloss
Publikováno v:
Gene Therapy. 10:1089-1098
Large bone defects resulting from nonunion fractures or tumour resections are common clinical problems. Recent studies have shown bone morphogenetic protein-2 (BMP-2) gene transfer using adenoviral vectors to be a promising new therapeutic approach.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2083bf4d4f6fa5a1f279845f1e5be03c
https://doi.org/10.1038/sj.gt.3301960
https://doi.org/10.1038/sj.gt.3301960
Publikováno v:
Journal of stem cellsregenerative medicine. 2(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::befdbf02721e9d86a03175957d5ff0ae
https://pubmed.ncbi.nlm.nih.gov/24692977
https://pubmed.ncbi.nlm.nih.gov/24692977
Publikováno v:
Mechanisms of Development. 109(2):389-393
Annexin A5 (annexin V, anchorin CII) represents the prototype member of the large annexin family, characterized by its ability to interact with phospholipids in a calcium-dependent manner and to form calcium-specific ion channels. Despite intense bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6f0bb3e0a3b95c6ab88cde4c5bb5a98
Autor:
K von der Mark, Qiu-Jie Jiang, Thomas Aigner, K. Wagner, Thomas Ritter, Holm Schneider, Ernst Pöschl, Kolja Gelse
Publikováno v:
Arthritis & Rheumatism. 44:1943-1953
Objective To assess the advantages and disadvantages of a direct adenoviral and a cell-mediated approach to the induction of cartilage formation in joints by transfer of growth factor genes. Methods Adenoviral vectors carrying insulin-like growth fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::252663af5158044df32dd69c5824f9c1
https://doi.org/10.1002/1529-0131(200108)44:8<1943::aid-art332>3.0.co
https://doi.org/10.1002/1529-0131(200108)44:8<1943::aid-art332>3.0.co
Publikováno v:
Calcified Tissue International. 63:263-268
The distribution and expression of type X collagen, a calcium-binding collagen, which is a marker of hypertrophic chondrocytes and thought to be involved in cartilage calcification, was examined in situ in nondegenerate (grade I or II) human discs ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02da6450eb0a469070a8207846cb5935
https://doi.org/10.1007/s002239900524
https://doi.org/10.1007/s002239900524
Autor:
Heli Salminen, Pirkko Lammi, Mikko J. Lammi, K von der Mark, Eero Vuorio, Iiro Eerola, Anna-Marja Säämänen
Publikováno v:
Arthritis & Rheumatism. 41:1287-1295
OBJECTIVE: To perform a systematic study on the production and deposition of type X collagen in developing, aging, and osteoarthritic (OA) mouse articular cartilage.METHODS: Immunohistochemistry was employed to define the distribution of type X colla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d6b9b605561246665efa6e736a02d25
https://doi.org/10.1002/1529-0131(199807)41:7<1287::aid-art20>3.0.co
https://doi.org/10.1002/1529-0131(199807)41:7<1287::aid-art20>3.0.co
Publikováno v:
Cell Calcium. 23:413-421
We recently showed that the C-terminal fragment PTH (52-84) effectively increases intracellular free calcium ([Ca2+]i) in a subset of growth plate chondrocytes not activated by the N-terminal PTH fragment (1-34). Here we characterize the active site
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60b7f607f9c9cbf51315539d202d286c
https://doi.org/10.1016/s0143-4160(98)90098-7
https://doi.org/10.1016/s0143-4160(98)90098-7