Zobrazeno 1 - 10
of 46
pro vyhledávání: '"K Y Hostetler"'
Publikováno v:
Journal of Lipid Research, Vol 17, Iss 4, Pp 433-437 (1976)
A two dimensional thin-layer chromatography system has been devised for the improved separation of phosphatidylglycerol and its derivatives, cardiolipin and bis(monoacylglyceryl)phosphate, from the other phospholipid components of tissue total lipid
Externí odkaz:
https://doaj.org/article/8ac1a7a47dc14918a47eac346395f65f
Autor:
Y Matsuzawa, K Y Hostetler
Publikováno v:
Journal of Lipid Research, Vol 21, Iss 2, Pp 202-214 (1980)
Administration of chloroquine or 4,4'-bis(diethylaminoethoxy)alpha, beta-diethyldiphenylethane (DH) to rats in oral doses of 100 mg/kg for 7 days causes phospholipid and cholesteryl ester accumulation in liver. To further characterize this drug-induc
Externí odkaz:
https://doaj.org/article/3b8523de4d644c4eaa09b60e80492e28
Publikováno v:
Journal of Lipid Research, Vol 20, Iss 5, Pp 607-613 (1979)
Mitochondria from the 7777 hepatoma incorporate substantial amounts of l-[U-(14)C]serine into phospholipid by a Ca(2+)-dependent base-exchange reaction. This reaction is virtually absent in normal liver mitochondria. The finding cannot be attributed
Externí odkaz:
https://doaj.org/article/37eb86c7b30b420e9ba485d67cd70e47
Autor:
K Y Hostetler, P J Yazaki
Publikováno v:
Journal of Lipid Research, Vol 20, Iss 4, Pp 456-463 (1979)
The subcellular distribution of neutral sphingomyelinase activity has been determined in rat liver. Neutral sphingomyelinase is present in the plasma membrane. This enzyme requires either Mg2+ or Mn2+ for full activity; these cations cannot be replac
Externí odkaz:
https://doaj.org/article/d9a4403f9dfc4b6dae2bade323c7aa6a
Publikováno v:
Journal of Lipid Research, Vol 19, Iss 5, Pp 553-560 (1978)
The subcellular and submitochondrial localization of CTP:phosphatidate cytidylyltransferase is altered in the Morris 7777 hepatoma. Mitochondria in this poorly differentiated tumor are the principal sites of CDP-diacylglycerol synthesis, in contrast
Externí odkaz:
https://doaj.org/article/3fed292bcbd3450ca9c81e015a2973f1
Autor:
B J Poorthuis, K Y Hostetler
Publikováno v:
Journal of Lipid Research, Vol 19, Iss 3, Pp 309-315 (1978)
Diphosphatidyl[1',2',3'-14C]glycerol (cardiolipin) is converted to bis(monoacylglyceryl)phosphate when incubated in vitro with rat lysosomes at pH 4.4. The stereochemical configuration of the product is unknown. This reaction probably takes place via
Externí odkaz:
https://doaj.org/article/ea7e92fb5a754a059c8d5e1078cdb0f2
Autor:
G Nalbone, K Y Hostetler
Publikováno v:
Journal of Lipid Research, Vol 26, Iss 1, Pp 104-114 (1985)
During myocardial ischemia increased levels of lysoglycerophospholipids have been reported which may be deleterious to myocardial function. Phospholipases are presumed to be important in the regulation of this process. To further quantify and charact
Externí odkaz:
https://doaj.org/article/551083353f454dba9df871f625bc4c3e
Autor:
L, Cheng, K Y, Hostetler, S, Chaidhawangul, M F, Gardner, J R, Beadle, K S, Keefe, G, Bergeron-Lynn, G M, Severson, K A, Soules, A J, Mueller, W R, Freeman
Publikováno v:
Investigative ophthalmologyvisual science. 41(6)
To evaluate the intraocular safety and antiviral treatment efficacy of the sustained lipid prodrug of ganciclovir, 1-O-hexadecylpropanediol-3-phospho-ganciclovir (HDP-P-GCV), as an intravitreal injectable drug system for viral retinitis.HDP-P-GCV was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ed5dc6ec0b0fbeefe04d4805d6181cd5
https://pubmed.ncbi.nlm.nih.gov/10798672
https://pubmed.ncbi.nlm.nih.gov/10798672
Autor:
L, Cheng, K Y, Hostetler, M F, Gardner, C P, Avila, G, Bergeron-Lynn, K S, Keefe, J R, Beadle, C A, Wiley, W R, Freeman
Publikováno v:
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. 15(4)
This study was conducted to evaluate the vitreous clarity and intraocular therapeutic index of three preparations ofthe carboxymethyl ester of 1-O-octadecyl-sn-glycerol-3-phosphonoformate (ODG-PFA-O-Me), a long acting lipid derivative of foscarnet wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::58229855e0a60c782746faf2397992bb
https://pubmed.ncbi.nlm.nih.gov/10463875
https://pubmed.ncbi.nlm.nih.gov/10463875
Autor:
L, Cheng, K Y, Hostetler, M F, Gardner, C P, Avila, G, Bergeron-Lynn, K S, Keefe, C A, Wiley, W R, Freeman
Publikováno v:
Investigative ophthalmologyvisual science. 40(7)
To determine intraocular toxicity and efficacy of the lipid prodrug of foscarnet, 1-O-octadecyl-sn-glycerol-3-phosphonoformate (ODG-PFA), as a long-acting, nontoxic intravitreous injectable drug delivery system for cytomegalovirus (CMV) retinitis.ODG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9b6090da2bc2c34b690863d6b68d63f2
https://pubmed.ncbi.nlm.nih.gov/10359331
https://pubmed.ncbi.nlm.nih.gov/10359331