Zobrazeno 1 - 10
of 78
pro vyhledávání: '"K Y, Hong"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract A key question in regulatory genomics is whether cis-regulatory elements (CREs) are modular elements that can function anywhere in the genome, or whether they are adapted to certain genomic locations. To distinguish between these possibiliti
Externí odkaz:
https://doaj.org/article/5493e21bd1fc4598b807a433f55e8a0a
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-23 (2024)
Abstract Background Individual cells from isogenic populations often display large cell-to-cell differences in gene expression. This “noise” in expression derives from several sources, including the genomic and cellular environment in which a gen
Externí odkaz:
https://doaj.org/article/fca7dcb5df5c4ddca2e1448f0336fda0
Autor:
Morgan B. Giles, Justin K. Y. Hong, Yayuan Liu, Jie Tang, Tinghui Li, Avital Beig, Anna Schwendeman, Steven P. Schwendeman
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Encapsulation of bioactive peptides in slow-release particles is complex and relies on organic solvents. Here, the authors absorb peptides in a polymer phase from water, creating a simple low-cost encapsulation process in a class of polymer depot.
Externí odkaz:
https://doaj.org/article/ea35ff6412aa4f5eb10b6b0ae683a965
Autor:
Siqi Zhao, Clarice K. Y. Hong, Connie A. Myers, David M. Granas, Michael A. White, Joseph C. Corbo, Barak A. Cohen
Publikováno v:
Nature Genetics. 55:346-354
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5864fd123f4f033ab2723354d9474ea8
https://doi.org/10.1038/s41588-022-01278-7
https://doi.org/10.1038/s41588-022-01278-7
Akademický článek
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Autor:
Steven P. Schwendeman, Bin Qin, Justin K Y Hong, Yan Wang, Alexander Benet, Jennifer Walker, Avital Beig, Jukyung Kang, Aishwarya Chandrashekar, Anna Schwendeman, Tinghui Li, Rose Ackermann
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 158:401-409
Bydureon® (Bdn) is a once-weekly injectable long-acting release (LAR) product for adults with type 2 diabetes based on PLGA microspheres encapsulating the glucagon like peptide (GLP-1) analog, exenatide. Despite its widespread use in type 2 diabetes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85086dc3f3c3d1b9afa32012171c69cb
https://doi.org/10.1016/j.ejpb.2020.10.008
https://doi.org/10.1016/j.ejpb.2020.10.008
Autor:
Li Li, Steven P. Schwendeman, Karl F. Olsen, Nian-Qiu Shi, Jie Tang, Rose Ackermann, Bin Qin, Jia Zhou, Jennifer Walker, Yan Wang, Justin K Y Hong, Anna Schwendeman
Publikováno v:
Journal of Controlled Release. 321:756-772
A spray drying technique was developed to prepare injectable and biodegradable poly(lactic-co-glycolic acid) (PLGA) microspheres encapsulating a model luteinizing hormone-releasing hormone agonist (LHRHa)-based peptide, leuprolide. Various spray dryi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::827844dce0c260e7fba4758608904efa
https://doi.org/10.1016/j.jconrel.2020.01.023
https://doi.org/10.1016/j.jconrel.2020.01.023
Publikováno v:
ANZ Journal of Surgery. 89:1642-1646
Background The role of service centralization in rectal cancer surgery is controversial. Recent studies suggest centralization to high-volume centres may improve postoperative mortality. We used a state-wide administrative data set to determine the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::524c82396a66248befc6abd785e681cc
https://doi.org/10.1111/ans.15546
https://doi.org/10.1111/ans.15546
Publikováno v:
Colorectal Disease. 21:1067-1072
AIM: Routine elective colectomy after acute diverticulitis is not recommended, yet significant numbers are still being performed. Amidst global concern over the rising costs of surgery and the value of healthcare, acute diverticulitis is a disease th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f70c4d5ad530cf04bfded1f78a40e83e
https://doi.org/10.1111/codi.14648
https://doi.org/10.1111/codi.14648
Autor:
Linglin Feng, Jennifer Walker, Steven P. Schwendeman, Yan Wang, Avital Beig, Rose Ackermann, Justin K Y Hong, Tinghui Li
Publikováno v:
Drug delivery and translational research. 12(3)
Sandostatin long-acting release® (SLAR) is a long-acting injectable somatostatin analogue formulation composed of octreotide encapsulated in glucose-initiated poly(lactic-co-glycolic acid) (PLGA) microspheres. Despite the end of patent protection, S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b7bd9e7f0722311940c50fa839ac27
https://pubmed.ncbi.nlm.nih.gov/34215997
https://pubmed.ncbi.nlm.nih.gov/34215997