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pro vyhledávání: '"K W Ranatunga"'
Autor:
K. W. Ranatunga, Gerald Offer
Publikováno v:
Biophys J
It is controversial whether the phosphate (Pi) release step in the cross-bridge cycle occurs before or after the first tension-generating step and whether it is fast or slow. We have therefore modified our previous model of the frog cross-bridge cycl
Autor:
K. W. Ranatunga, M. A. Geeves
Publikováno v:
International Journal of Molecular Sciences. 24:5031
Findings from experiments that used hydrostatic pressure changes to analyse the process of skeletal muscle contraction are re-examined. The force in resting muscle is insensitive to an increase in hydrostatic pressure from 0.1 MPa (atmospheric) to 10
Publikováno v:
Journal of Muscle Research and Cell Motility. 40:275-278
Autor:
K. W. Ranatunga, Gerald Offer
Publikováno v:
The Journal of Physiology. 593:1997-2016
The isometric tetanic tension of skeletal muscle increases with temperature because attached crossbridge states bearing a relatively low force convert to those bearing a higher force. It was previously proposed that the tension-generating step(s) in
Autor:
Gerald Offer, K. W. Ranatunga
Publikováno v:
Journal of Experimental Biology.
In experiments on active muscle, we examined the tension decline and its temperature sensitivity at the onset of ramp shortening and at a range of velocities. A segment (∼1.5 mm long) of a skinned muscle fibre isolated from rabbit psoas muscle was
Autor:
Gerald Offer, K. W. Ranatunga
Publikováno v:
Biophysical Journal. 105(4):928-940
We examined whether cross-bridge cycle models with one or two tension-generating steps can account for the force-velocity relation of and tension response to length steps of frog skeletal muscle. Transition-state theory defined the strain dependence
Autor:
K. W. Ranatunga
Publikováno v:
Muscle Contraction and Cell Motility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5edf6c5b6d7bc4aec2230d5be4873dce
https://doi.org/10.1201/9781315364674-6
https://doi.org/10.1201/9781315364674-6
Autor:
K. W. Ranatunga, Gerald Offer
Publikováno v:
Biophysical journal. 111(9)
We have reexamined the experimental time courses of tension in frog muscle after rapid length steps. The early tension recoveries are biexponential. After 3 nm/hs stretches and releases, the rates of the immediate rapid tension changes are similar bu
Autor:
K. W. Ranatunga, Gerald Offer
Publikováno v:
Journal of Muscle Research and Cell Motility. 31:245-265
The stiffness of myosin heads attached to actin is a crucial parameter in determining the kinetics and mechanics of the crossbridge cycle. It has been claimed that the stiffness of myosin heads in the anterior tibialis muscle of the common frog (Rana
Autor:
K. W. Ranatunga
Publikováno v:
The Journal of Physiology. 588:3657-3670
The basic characteristics of the process of force and power generation in active muscle that have emerged from temperature studies are examined. This is done by reviewing complementary findings from temperature-dependence studies and rapid temperatur