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Autor:
Lilian I. Plotkin, G D Roodman, S A Kuhstoss, Teresita Bellido, Judith L. Anderson, Jesus Delgado-Calle, Meloney Cregor, K W Condon
Publikováno v:
Leukemia
Multiple myeloma (MM) causes lytic bone lesions due to increased bone resorption and concomitant marked suppression of bone formation. Sclerostin (Scl) levels, an osteocyte-derived inhibitor of Wnt/β-catenin signaling, are elevated in MM patient ser